KEGG   DRUG: D10152Help
Entry
D10152                      Drug                                   

Name
Prucalopride succinate (USAN);
Resolor (TN)
Formula
C18H26ClN3O3. C4H6O4
Exact mass
485.1929
Mol weight
485.9584
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Treatment of constipation
Remark
ATC code: 
Drug group: 
Target
5-HT4-receptor agonist [HSA:3360] [KO:K04160]
  Pathway
hsa04020  Calcium signaling pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 A ALIMENTARY TRACT AND METABOLISM
  A06 DRUGS FOR CONSTIPATION
   A06A DRUGS FOR CONSTIPATION
    A06AX Other drugs for constipation
     A06AX05 Prucalopride
      D10152  Prucalopride succinate (USAN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Serotonin
    5-HT4-receptor
     Prucalopride
      D10152  Prucalopride succinate (USAN)
BRITE hierarchy
Other DBs
CAS: 
179474-85-2
PubChem: 
LigandBox: 
KCF data Show

ATOM        33
            1   O6a O    23.6025  -14.2002
            2   C6a C    24.8204  -14.9034
            3   C1b C    26.0213  -14.2099
            4   O6a O    24.8205  -16.3096
            5   C1b C    27.2141  -14.8985
            6   C6a C    28.4107  -14.2074
            7   O6a O    29.6056  -14.8972
            8   O6a O    28.4107  -12.7942
            9   C8y C    14.4200  -17.0800
            10  C8y C    14.4200  -15.6800
            11  C8y C    15.6100  -14.9800
            12  C8y C    16.8700  -15.6800
            13  C8y C    16.8700  -17.0800
            14  C8x C    15.6100  -17.7800
            15  C1x C    16.1700  -13.5800
            16  C1x C    17.5000  -13.5800
            17  O2x O    17.9900  -14.8400
            18  N1a N    13.1600  -14.9800
            19  X   Cl   13.1600  -17.7800
            20  C5a C    18.0600  -17.8500
            21  N1b N    19.3200  -17.1500
            22  O5a O    18.0600  -19.2500
            23  C1y C    20.5100  -17.7800
            24  C1x C    21.7000  -17.1500
            25  C1x C    22.8900  -17.8500
            26  N1y N    22.8900  -19.2500
            27  C1x C    21.7000  -19.9500
            28  C1x C    20.5100  -19.2500
            29  C1b C    24.1500  -19.9500
            30  C1b C    25.3400  -19.2500
            31  C1b C    26.5300  -19.9500
            32  O2a O    27.7200  -19.2500
            33  C1a C    28.9100  -19.9500
BOND        34
            1     1   2 1
            2     2   3 1
            3     2   4 2
            4     3   5 1
            5     5   6 1
            6     6   7 1
            7     6   8 2
            8     9  10 2
            9    10  11 1
            10   11  12 2
            11   12  13 1
            12   13  14 2
            13    9  14 1
            14   11  15 1
            15   15  16 1
            16   16  17 1
            17   12  17 1
            18   10  18 1
            19    9  19 1
            20   13  20 1
            21   20  21 1
            22   20  22 2
            23   21  23 1
            24   23  24 1
            25   24  25 1
            26   25  26 1
            27   26  27 1
            28   27  28 1
            29   23  28 1
            30   26  29 1
            31   29  30 1
            32   30  31 1
            33   31  32 1
            34   32  33 1

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