KEGG   DRUG: D00455Help
エントリ  
D00455                      Drug                                   

一般名   
オメプラゾール (JP16);
Omeprazole (JP16/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
OMEPRAZOLE (Aidarex Pharmaceuticals LLC), OMEPRAZOLE (Aidarex Pharmaceuticals LLC), OMEPRAZOLE (Altura Pharmaceuticals), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Apotex Corp), OMEPRAZOLE (AvPAK), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Cadila Healthcare Limited), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Clinical Solutions Wholesale), OMEPRAZOLE (Contract Pharmacy Services-PA), OMEPRAZOLE (Dispensing Solutions), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (H.J. Harkins Company), OMEPRAZOLE (KAISER FOUNDATION HOSPITALS), OMEPRAZOLE (KAISER FOUNDATION HOSPITALS), OMEPRAZOLE (Kremers Urban Pharmaceuticals), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Legacy Pharmaceutical Packaging), OMEPRAZOLE (Legacy Pharmaceutical Packaging), OMEPRAZOLE (Life Line Home Care Services), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (McKesson Contract Packaging), OMEPRAZOLE (McKesson Packaging Services a business unit of McKesson Corporation), OMEPRAZOLE (Medsource Pharmaceuticals), OMEPRAZOLE (Mylan Institutional), OMEPRAZOLE (Mylan Pharmaceuticals), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (New Horizon Rx Group), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (Physicians Total Care), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (Rebel Distributors Corp), OMEPRAZOLE (Rebel Distributors Corp), OMEPRAZOLE (Rebel Distributors Corp.), OMEPRAZOLE (STAT Rx USA LLC), OMEPRAZOLE (STAT Rx USA LLC), OMEPRAZOLE (Sandoz), OMEPRAZOLE (St Marys Medical Park Pharmacy), OMEPRAZOLE (State of Florida DOH Central Pharmacy), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Watson Pharma), OMEPRAZOLE (Zydus Pharmaceuticals (USA))
組成式   
C17H19N3O3S
質量    
345.1147
分子量   
345.4161
構造式   
Mol fileKCF fileDB searchJmolKegDraw
効能    
消化性潰瘍用薬, プロトンポンプ阻害薬 [DS:H00045]
注釈1   
同一化合物: C07324
薬効分類: 2329
ATCコード: A02BC01
注釈2   
適応症: 胃・十二指腸潰瘍, 逆流性食道炎, 吻合部潰瘍, Zollinger-Ellison症候群; 次の疾患におけるヘリコバクター・ピロリの除菌の補助 (胃潰瘍・十二指腸潰瘍・胃MALTリンパ腫・特発性血小板減少性紫斑病・早期胃癌に対する内視鏡的治療後胃・ヘリコバクター・ピロリ感染胃炎)
プロドラッグ
ターゲット 
H+/K+ exchanging, alpha polypeptide inhibitor [HSA:495] [KO:K01542];
H+/K+ exchanging, beta polypeptide inhibitor [HSA:496] [KO:K01543]
  パスウェイ
hsa00190  酸化的リン酸化
hsa04966  集合管における酸の分泌
hsa04971  胃酸の分泌  
 
代謝    
Enzyme: CYP2C19 [HSA:1557], CYP3A4 [HSA:1576]
相互作用  
Genomic biomarker: CYP2C19 [HSA:1557]
CYP induction: CYP1A2 [HSA:1544]
CYP inhibition: CYP2C19 [HSA:1557]
Drug interaction
構造マップ 
抗消化性潰瘍薬
イオントランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  23  消化器官用薬
   232  消化性潰瘍用剤
    2329  その他の消化性潰瘍用剤
     D00455  オメプラゾール (JP16)
医療用医薬品のATC分類 [BR:jp08303]
 A 消化管と代謝作用
  A02 胃酸関連疾患用薬
   A02B 消化性潰瘍と胃食道逆流用薬
    A02BC プロトンポンプ阻害薬
     A02BC01 オメプラゾール
      D00455  オメプラゾール (JP16)
医療用医薬品のUSP分類 [BR:jp08302]
 胃腸薬
  プロトンポンプ阻害薬
   オメプラゾール
    D00455  オメプラゾール (JP16)
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  加水分解酵素
   H+/K+-交換, αポリペプチド [HSA:495 496] [KO:K01542 K01543]
    オメプラゾール [atc:A02BC01]
     D00455  オメプラゾール (JP16)
BRITE hierarchy
リンク   
CAS: 
73590-58-6
PubChem: 
DrugBank: 
LigandBox: 
日化辞: 

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