KEGG   DRUG: オメプラゾールHelp
エントリ  
D00455                      Drug                                   

一般名   
オメプラゾール (JP17);
Omeprazole (JP17/USP/INN)
商品名   
  後発品
米国の商品 
  後発品
OMEPRAZOLE (A-S Medication Solutions), OMEPRAZOLE (Actavis Pharma), OMEPRAZOLE (Aidarex Pharmaceuticals LLC), OMEPRAZOLE (Aidarex Pharmaceuticals LLC), OMEPRAZOLE (Altura Pharmaceuticals), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (American Health Packaging), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Aphena Pharma Solutions - Tennessee), OMEPRAZOLE (Apotex Corp), OMEPRAZOLE (Aurobindo Pharma Limited), OMEPRAZOLE (AvPAK), OMEPRAZOLE (Avera McKennan Hospital), OMEPRAZOLE (Blenheim Pharmacal), OMEPRAZOLE (Blenheim Pharmacal), OMEPRAZOLE (Blenheim Pharmacal), OMEPRAZOLE (Blenheim Pharmacal), OMEPRAZOLE (Breckenridge Pharmaceutical), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Bryant Ranch Prepack), OMEPRAZOLE (Cadila Healthcare Limited), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Cardinal Health), OMEPRAZOLE (Carilion Materials Management), OMEPRAZOLE (Citron Pharma LLC), OMEPRAZOLE (Clinical Solutions Wholesale), OMEPRAZOLE (Contract Pharmacy Services-PA), OMEPRAZOLE (Contract Pharmacy Services-PA), OMEPRAZOLE DELAYED-RELEASE (DOH CENTRAL PHARMACY), OMEPRAZOLE (Denton Pharma), OMEPRAZOLE (Dispensing Solutions), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Dr. Reddy's Laboratories Limited), OMEPRAZOLE (Glenmark Pharmaceuticals), OMEPRAZOLE (Glenmark Pharmaceuticals), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (Golden State Medical Supply), OMEPRAZOLE (H.J. Harkins Company), OMEPRAZOLE (KAISER FOUNDATION HOSPITALS), OMEPRAZOLE (KAISER FOUNDATION HOSPITALS), OMEPRAZOLE (Kremers Urban Pharmaceuticals), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Lake Erie Medical DBA Quality Care Products LLC), OMEPRAZOLE (Life Line Home Care Services), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (Major Pharmaceuticals), OMEPRAZOLE (Mas Management Group), OMEPRAZOLE (McKesson Corporation), OMEPRAZOLE (Medsource Pharmaceuticals), OMEPRAZOLE (Midwest Drug Distribution), OMEPRAZOLE (Mylan Institutional), OMEPRAZOLE (Mylan Pharmaceuticals), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (NCS HealthCare of KY), OMEPRAZOLE (New Horizon Rx Group), OMEPRAZOLE (NorthStar Rx LLC), OMEPRAZOLE (Northwind Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCare Pharmaceuticals), OMEPRAZOLE (NuCarePharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (PD-Rx Pharmaceuticals), OMEPRAZOLE (Physicians Total Care), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Preferred Pharmaceuticals), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (Proficient Rx LP), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (REMEDYREPACK), OMEPRAZOLE (RPK Pharmaceuticals), OMEPRAZOLE (ReadyMeds), OMEPRAZOLE (Rebel Distributors Corp), OMEPRAZOLE (Rebel Distributors Corp), OMEPRAZOLE (Rebel Distributors Corp.), OMEPRAZOLE (RedPharm Drug), OMEPRAZOLE (RedPharm Drug), OMEPRAZOLE (RxChange), OMEPRAZOLE (Safecor Health), OMEPRAZOLE (Sandoz), OMEPRAZOLE (Sandoz), OMEPRAZOLE (St. Mary's Medical Park Pharmacy), OMEPRAZOLE (St. Mary's Medical Park Pharmacy), OMEPRAZOLE (State of Florida DOH Central Pharmacy), OMEPRAZOLE (State of Florida DOH Central Pharmacy), OMEPRAZOLE (TYA Pharmaceuticals), OMEPRAZOLE (Teva Pharmaceuticals USA), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Unit Dose Services), OMEPRAZOLE (Zydus Pharmaceuticals (USA)), OMEPRAZOLE AND SODIUM BICARBONATE (Aurolife Pharma), OMEPRAZOLE AND SODIUM BICARBONATE (Medarbor Llc), OMEPRAZOLE AND SODIUM BICARBONATE (Medarbor Llc), OMEPRAZOLE/SODIUM BICARBONATE (Par Pharmaceutical), OMEPRAZOLE AND SODIUM BICARBONATE (ScieGen Pharmaceuticals), OMEPRAZOLE DR (Direct Rx), OMEPRAZOLE (Northwind Pharmaceuticals)
組成式   
C17H19N3O3S
質量    
345.1147
分子量   
345.4161
構造式   
Mol fileKCF fileDB searchJmolKegDraw
Simcomp    SIMCOMP
クラス   
消化器系用薬
 DG01646  プロトンポンプ阻害薬 (PPI)
 DG01975  消化性潰瘍薬
  DG01646  プロトンポンプ阻害薬 (PPI)
Cyp 基質
 DG01639  CYP2C19により代謝される薬剤
 DG01633  CYP3Aにより代謝される薬剤
Cyp 阻害
 DG01933  CYP2C19阻害薬
Cyp 誘導
 DG01637  CYP1A2誘導薬
コード   
同一コード: C07324
薬効分類: 2329
ATCコード: A02BC01
化学構造グループ: DG00020
商品(DG00020): D00455<JP/US> D05261<JP> D05259<US>
商品(mixture): D10246<US>
効能    
胃酸分泌抑制薬, 消化性潰瘍薬, プロトンポンプ阻害薬
  疾患
胃潰瘍 [DS:H01634]
十二指腸潰瘍 [DS:H01634]
吻合部潰瘍 [DS:H01634]
逆流性食道炎 [DS:H01602]
Zollinger-Ellison症候群 [DS:H01522]
ヘリコバクター・ピロリの除菌の補助 [DS:H00320]
コメント  
ベンゾイミダゾール誘導体
ターゲット 
ATP4 [HSA:495 496] [KO:K01542 K01543]
  パスウェイ
hsa04966  集合管における酸の分泌
hsa04971  胃酸の分泌
代謝    
Enzyme: CYP2C19 [HSA:1557]; CYP3A4 [HSA:1576]
相互作用  
CYP induction: CYP1A2 [HSA:1544]
CYP inhibition: CYP2C19 [HSA:1557]
Drug interaction
構造マップ 
map07038  抗消化性潰瘍薬
map07233  イオントランスポーター阻害薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 2  個々の器官系用医薬品
  23  消化器官用薬
   232  消化性潰瘍用剤
    2329  その他の消化性潰瘍用剤
     D00455  オメプラゾール (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 A 消化管と代謝作用
  A02 胃酸関連疾患用薬
   A02B 消化性潰瘍と胃食道逆流用薬
    A02BC プロトンポンプ阻害薬
     A02BC01 オメプラゾール
      D00455  オメプラゾール (JP17)
医療用医薬品のUSP分類 [BR:jp08302]
 胃腸薬
  プロトンポンプ阻害薬
   オメプラゾール
    D00455  オメプラゾール (JP17)
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  加水分解酵素
   H+/K+-交換, αポリペプチド
    オメプラゾール
     D00455  オメプラゾール (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00455  オメプラゾール
  D00455  オメプラゾール腸溶錠
治療薬の医薬品クラス [jp08360.html]
 消化器官用薬
  D00455
添付文書記載のゲノムバイオマーカー [jp08342.html]
 遺伝子多型と変異
  D00455
BRITE hierarchy
リンク   
CAS: 73590-58-6
PubChem: 7847521
ChEBI: 77260 7772
ChEMBL: CHEMBL1503
DrugBank: DB00338
LigandBox: D00455
日化辞: J33.884B

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