KEGG   DRUG: ワルファリンナトリウムHelp
エントリ  
D00564                      Drug                                   

一般名   
ワルファリンナトリウム;
Warfarin sodium (USP)
米国の商品 
  後発品
WARFARIN SODIUM (Aidarex Pharmaceuticals LLC), WARFARIN SODIUM (Amneal Pharmaceuticals), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Exelan Pharmaceuticals), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (A-S Medication Solutions), WARFARIN SODIUM (Aidarex Pharmaceuticals LLC), WARFARIN SODIUM (Aidarex Pharmaceuticals LLC), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (American Health Packaging), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Aphena Pharma Solutions - Tennessee), WARFARIN SODIUM (Barr Laboratories), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Bryant Ranch Prepack), WARFARIN SODIUM (Cadila Healthcare Limited), WARFARIN SODIUM (Camber Pharmaceuticals), JANTOVEN (Cardinal Health), WARFARIN SODIUM (Citron Pharma LLC), WARFARIN SODIUM (Clinical Solutions Wholesale), WARFARIN SODIUM (Clinical Solutions Wholesale), WARFARIN SODIUM (Clinical Solutions Wholesale), WARFARIN SODIUM (DirectRX), WARFARIN SODIUM (Golden State Medical Supply), WARFARIN SODIUM (KAISER FOUNDATION HOSPITALS), WARFARIN SODIUM (Lake Erie Medical DBA Quality Care Products LLC), WARFARIN SODIUM (Lake Erie Medical DBA Quality Care Products LLC), WARFARIN SODIUM (Lake Erie Medical DBA Quality Care Products LLC), WARFARIN SODIUM (Med-Health Pharma), WARFARIN SODIUM (New Horizon Rx Group), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (Northwind Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (PD-Rx Pharmaceuticals), WARFARIN SODIUM (Physicians Total Care), WARFARIN SODIUM (Physicians Total Care), WARFARIN SODIUM (Proficient Rx LP), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), JANTOVEN (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (REMEDYREPACK), WARFARIN SODIUM (ReadyMeds), WARFARIN SODIUM (Rebel Distributors Corp), WARFARIN SODIUM (STAT Rx USA LLC), WARFARIN SODIUM (STAT Rx USA LLC), WARFARIN SODIUM (St Marys Medical Park Pharmacy), WARFARIN SODIUM (St Marys Medical Park Pharmacy), WARFARIN SODIUM (State of Florida DOH Central Pharmacy), WARFARIN SODIUM (TYA Pharmaceuticals), WARFARIN SODIUM (TYA Pharmaceuticals), WARFARIN SODIUM (Taro Pharmaceuticals U.S.A.), WARFARIN SODIUM (Teva Pharmaceuticals USA), WARFARIN SODIUM (Unit Dose Services), WARFARIN SODIUM (Unit Dose Services), WARFARIN SODIUM (Unit Dose Services), WARFARIN SODIUM (Unit Dose Services), WARFARIN SODIUM (Unit Dose Services), WARFARIN SODIUM (Unit Dose Services), JANTOVEN (Upsher-Smith Laboratories), WARFARIN SODIUM (Zydus Pharmaceuticals (USA))
組成式   
C19H15O4. Na
質量    
330.0868
分子量   
330.3098
構造式   
Mol fileKCF fileDB searchJmolKegDraw
クラス   
循環器系用薬
 DG01708  クマリン系抗凝固薬
  DG01760  ワルファリンと類似体
Cyp 基質
 DG01892  CYP1A2により代謝される薬剤
 DG01642  CYP2C9により代謝される薬剤
コード   
ATCコード: B01AA03
Chemical グループ: DG00149
効能    
血栓症の予防・治療薬
ターゲット 
vitamin-K-epoxide reductase [HSA:79001] [KO:K05357];
phylloquinone reductase [HSA:1728] [KO:K00355]
  パスウェイ
ユビキチンとその他のテルペノイド・キノンの生合成
代謝    
Enzyme: CYP2C9 [HSA:1559], CYP1A2 [HSA:1544]
相互作用  
Genomic biomarker: VKORC1 [HSA:79001], CYP2C9 [HSA:1559]
Drug interaction
構造マップ 
抗血栓症薬
階層分類  
医療用医薬品のATC分類 [BR:jp08303]
 B 血液と造血器官
  B01 抗血栓薬
   B01A 抗血栓薬
    B01AA ビタミンK拮抗薬
     B01AA03 ワルファリン
      D00564  ワルファリンナトリウム
医療用医薬品のUSP分類 [BR:jp08302]
 血液製剤/血液調節薬/血液量増量剤
  抗凝血薬
   ワルファリン
    D00564  ワルファリンナトリウム
ターゲットに基づく医薬品分類 [BR:jp08310]
 酵素
  酸化還元酵素
   ビタミンKエポキシドレダクターゼ
    ワルファリン
     D00564  ワルファリンナトリウム
   フィロキノンレダクターゼ
    ワルファリン
     D00564  ワルファリンナトリウム
チトクローム P450 の相互作用 [BR:jp08309]
 CYP基質
  CYP1A2
   ワルファリン
    D00564  ワルファリンナトリウム
  CYP2C9
   ワルファリン
    D00564  ワルファリンナトリウム
米国添付文書記載のゲノムバイオマーカー [jp08341.html]
 遺伝子多型と変異
  D00564
BRITE hierarchy
リンク   
CAS: 
129-06-6
PubChem: 
DrugBank: 
LigandBox: 
日化辞: 

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