KEGG   DRUG: D05008Help
エントリ  
D05008                      Drug                                   

一般名   
塩酸メトクロプラミド;
Metoclopramide hydrochloride (USAN);
Metoclopramide hydrochloride monohydrate
米国の商品 
  後発品
METOCLOPRAMIDE (A-S Medication Solutions LLC), METOCLOPRAMIDE (ANIP Acquisition Company), METOCLOPRAMIDE (Actavis Elizabeth LLC), METOCLOPRAMIDE (Aidarex Pharmaceuticals LLC), METOCLOPRAMIDE (American Health Packaging), METOCLOPRAMIDE (Bryant Ranch Prepack), METOCLOPRAMIDE (Cardinal Health), METOCLOPRAMIDE (Cardinal Health), METOCLOPRAMIDE (Lake Erie Medical DBA Quality Care Products LLC), METOCLOPRAMIDE (Liberty Pharmaceuticals), METOCLOPRAMIDE (McKesson Contract Packager), METOCLOPRAMIDE (NCS HealthCare of KY), METOCLOPRAMIDE (NCS HealthCare of KY), METOCLOPRAMIDE (NCS HealthCare of KY), METOCLOPRAMIDE (Par Pharmaceutical), METOCLOPRAMIDE (Physicians Total Care), METOCLOPRAMIDE (Preferred Pharmaceuticals), METOCLOPRAMIDE (Preferred Pharmaceuticals), METOCLOPRAMIDE (Qualitest Pharmaceuticals), METOCLOPRAMIDE (REMEDYREPACK), METOCLOPRAMIDE (REMEDYREPACK), METOCLOPRAMIDE (REMEDYREPACK), METOCLOPRAMIDE (REMEDYREPACK), METOCLOPRAMIDE (REMEDYREPACK), METOCLOPRAMIDE (Ranbaxy Pharmaceuticals), METOCLOPRAMIDE (Rebel Distributors Corp.), METOCLOPRAMIDE (State of Florida DOH Central Pharmacy), METOCLOPRAMIDE (Teva Pharmaceuticals USA), METOCLOPRAMIDE (UDL Laboratories), METOCLOPRAMIDE (ANIP Acquisition Company), METOCLOPRAMIDE (American Health Packaging), METOCLOPRAMIDE (BD Rx), METOCLOPRAMIDE HYDROCHLORIDE (Bryant Ranch Prepack), METOCLOPRAMIDE (Cardinal Health), METOCLOPRAMIDE (Cardinal Health), METOCLOPRAMIDE HYDROCHLORIDE (Cardinal Health), METOCLOPRAMIDE (Heritage Pharmaceuticals), METOCLOPRAMIDE (Hospira), METOCLOPRAMIDE (McKesson Contract Packaging), METOCLOPRAMIDE (McKesson Contract Packaging), METOCLOPRAMIDE HYDROCHLORIDE (McKesson Packaging Services a business unit of McKesson Corporation), METOCLOPRAMIDE (Morton Grove Pharmaceuticals), METOCLOPRAMIDE HYDROCHLORIDE (Northstar RxLLC), METOCLOPRAMIDE (Pharmaceutical Associates), METOCLOPRAMIDE (Precision Dose), METOCLOPRAMIDE HYDROCHLORIDE (Preferred Pharmaceuticals), METOCLOPRAMIDE HYDROCHLORIDE (REMEDYREPACK), METOCLOPRAMIDE HYDROCHLORIDE (REMEDYREPACK), METOCLOPRAMIDE HYDROCHLORIDE (Rebel Distributors Corp), METOCLOPRAMIDE HYDROCHLORIDE (Rebel Distributors Corp), METOCLOPRAMIDE (STAT RX USA LLC), METOCLOPRAMIDE (Teva Parenteral Medicines), METOCLOPRAMIDE HYDROCHLORIDE (VistaPharm), METOCLOPRAMIDE HYDROCHLORIDE (Watson Laboratories)
組成式   
C14H22ClN3O2. HCl. H2O
質量    
353.1273
分子量   
354.2726
構造式   
Mol fileKCF fileDB searchJmolKegDraw
効能    
制吐薬
注釈1   
ATCコード: A03FA01
ターゲット 
dopamine D2-receptor antagonist [HSA:1813] [KO:K04145];
5-HT4-receptor agonist [HSA:3360] [KO:K04160];
5-HT3-receptor antagonist [HSA:3359 9177 170572 200909 285242] [KO:K04819]
  パスウェイ
hsa04020  カルシウムシグナル伝達経路
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04540  ギャップ結合  
 
代謝    
Enzyme: CYP2D6 [HSA:1565]
相互作用  
Genomic biomarker: CYB5R [HSA:51706 51700 1727 51167]
CYP inhibition: CYP2D6 [HSA:1565]
Drug interaction
構造マップ 
抗精神病薬
抗片頭痛薬
セロトニン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品のATC分類 [BR:jp08303]
 A 消化管と代謝作用
  A03 機能的胃腸疾患用薬
   A03F 運動改善薬
    A03FA 運動改善薬
     A03FA01 メトクロプラミド
      D05008  塩酸メトクロプラミド
医療用医薬品のUSP分類 [BR:jp08302]
 制吐薬
  その他制吐薬
   メトクロプラミド
    D05008  塩酸メトクロプラミド
 胃腸薬
  その他胃腸薬
   メトクロプラミド
    D05008  塩酸メトクロプラミド
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   ドパミン
    ドパミンD2-受容体 [HSA:1813] [KO:K04145]
     メトクロプラミド [atc:A03FA01]
      D05008  塩酸メトクロプラミド
   セロトニン
    5-HT3-受容体 [HSA:3359 9177 170572 200909 285242] [KO:K04819]
     メトクロプラミド [atc:A03FA01]
      D05008  塩酸メトクロプラミド
BRITE hierarchy
リンク   
CAS: 
54143-57-6
PubChem: 
DrugBank: 
LigandBox: 
日化辞: 

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