KEGG T01004: 100001532

Danio rerio (zebrafish): 100001532

Entry

100001532 CDS T01004

Gene name

plcb3, Plcbeta3, she, si:ch211-188c22.1, si:zc188c22.1, wu:fl04b08

Definition

phospholipase C, beta 3 (phosphatidylinositol-specific) (EC:3.1.4.11)

Orthology

K05858

phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]

Organism

dre Danio rerio (zebrafish)

Pathway

dre00562	Inositol phosphate metabolism
dre01100	Metabolic pathways
dre04020	Calcium signaling pathway
dre04070	Phosphatidylinositol signaling system
dre04270	Vascular smooth muscle contraction
dre04310	Wnt signaling pathway
dre04540	Gap junction
dre04912	GnRH signaling pathway
dre04916	Melanogenesis

Module

dre_M00130

Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4

Class

Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:dre00562]
Environmental Information Processing; Signal transduction; Wnt signaling pathway [PATH:dre04310]
Environmental Information Processing; Signal transduction; Calcium signaling pathway [PATH:dre04020]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:dre04070]
Cellular Processes; Cell communication; Gap junction [PATH:dre04540]
Organismal Systems; Endocrine system; GnRH signaling pathway [PATH:dre04912]
Organismal Systems; Endocrine system; Melanogenesis [PATH:dre04916]
Organismal Systems; Circulatory system; Vascular smooth muscle contraction [PATH:dre04270]

SSDB

Motif

Pfam:

PLC-beta_C PI-PLC-X PI-PLC-Y EF-hand_like C2 DUF1154

Other DBs

NCBI-GI:

NCBI-GeneID:

ZFIN:

UniProt:

Position

AA seq 1244 aa
MAGAKPGVHALQLKPVSVNEVLKRGSKFIKWDEEANSTPSLITLRVDPNGFFLYWTGGTS
MEAEILDMSHIRDTRTGKFAKTPKDQRIREMLFSGKADGNSDSRLLTVVYGNDLVNISFL
NFQAVQDGYCKLWTDELFKLATNMLSQNASRNTFLLKAYTKLKLQVTQDGKIPVKNILKM
FSDKKRVEMALEHCGLIFNRVDGIKPDDFTWEMFQNFLNKLSPRPEVERIFVDLGSKGKP
FLSLDQLMDFINRKQRDSRLNEVLYPPLKRDQVRQLMEKYETNTSQLERDQISLMSFTKY
LGGEENTVVPPERLDIIDDMNQPLSHYFINSSHNTYLTVGQLTGLSSVEMYRQVLLTGCR
CIELDCWKGRPPEEEPIITHGFTMTTEIPFKDVIEAIAESAFKTSPYPLILSFENHVDSA
KQQAKMAEYCRSMFGDALLIDPLDKYPLVPGQQLPSPQELLGKILIKNKKKHHHRASNGG
SIRRKDGTDEQSSPLNDCPLSDGDVGQLMSNGGEKLAERMAKDHDNSKSIDRGDGESDEE
EEEEPIPDPKKHNNTDEGTAYSEVNATEEMSTLVNYIEPVKFKSFEVAAKRKKFFEMSSF
VETKGMDTLKNSPTEFVEYNKKQMSRIYPKGTRVDSSNYMPQLFWNVGCQMVALNFQTLD
LAMQLNMGVFEYNGRCGYLLKPEFMRRTDKHFDPFTTDIVDGIVANTVKVKIISGQFLND
KKVGVYVEVDMFGLPADTKRKYRTKTSNNNSLDPVWDDETFVFNKVVLPTLASLRVAVYE
ENGKFIGHRILPVSALRPGYHYICLKNELNQPLMLPSLLVYTEVQDYIPNEHQEYAEALT
NPIKHLSLLAQRESQLLALMEDPTEGGPTKQEEGDGTDSSCVTSADPIFPLPSSPTLPSV
PTDLNPPPSGQKEDLVNNVLKVIEPESIDELKQHNSYLKLLKKQCKEFKELSKKHLKKML
ALSKEQKTLFNQQSSELQRKRSQIEKRIRTSLKKNGSEDSVHRELNELDLELQKQMEQFR
EEHMQKLLVLRQGQLQMEKEVKQFHLKEANQKLKDIAIECQAAQIKKLKDVCDKEKKELQ
KMLDRKRLNSIVEARKAEKEIDVNEINRKHIQESVSLIRQLEVSQGKRQEKLKALHKDIL
QKIEEEIPMNQARLTRDFEAELKRLPEEISQYLQELESKGSRKDSLMGQTNDGPNSGPPS
NCSTPPYSSPNHSWSNIANVSSLLLDSSTSSTSAKSETDTTGVY

NT seq 3735 nt +upstreamnt +downstreamnt
atggccggggcgaaaccgggagttcacgcgttgcagctcaaaccggtgtctgtcaatgag
gtcctcaaacgggggagcaagtttatcaaatgggacgaggaggccaacagcacacccagc
ctgatcaccctcagagtggacccaaatggattctttctttactggactggaggaaccagc
atggaagcggaaatcctggacatgagtcatatcagggacaccaggacagggaagtttgct
aagacgccaaaggaccaacgtattcgtgaaatgttgttttcgggcaaagcagatgggaac
tctgactcaaggctgctaacggtcgtctacggcaacgacctggtcaacatctctttcctc
aacttccaagctgtgcaggatggctattgcaagttgtggacggatgaactgtttaaactt
gccacaaatatgctgtcccagaatgcttcccgcaacaccttcttactcaaagcttacaca
aagctaaagttgcaggtaactcaggatgggaaaatcccagtaaagaacatcctaaaaatg
ttctcggataagaaacgtgtggagatggcgctggagcactgcggtcttatctttaacagg
gtggacggtataaaaccagatgacttcacctgggaaatgttccagaactttttaaacaaa
ctaagtcccagaccagaggtggagcgaatttttgtagatctagggtctaaagggaagccc
ttcttgtccttggatcagttgatggacttcataaatcgcaaacagagggattcacgacta
aatgaggttctttaccctccactcaaacgagatcaggtccgccagctcatggagaaatat
gagaccaacaccagccagctggagagagatcagatctccctgatgagcttcacaaagtat
cttggcggagaggaaaacactgtggttccccctgagaggctggacattatcgatgatatg
aaccagccgctgtcccactatttcatcaactcatcacacaacacataccttacggtgggg
cagctgacaggcctgtcttcagttgagatgtacagacaggtgttgctgacaggatgccgc
tgtatagagctggattgttggaagggccgcccacctgaagaagagccaatcatcactcat
ggtttcaccatgacaactgagatcccattcaaggatgtgattgaagccattgctgaaagt
gctttcaagacgtcaccttaccctctcatcctgtcctttgagaaccacgtggactcagca
aagcagcaggctaaaatggctgaatattgtcgctcaatgtttggggatgcgctgctcatt
gacccactggacaaatatccgctggttcctggtcaacaactcccaagcccccaggagctg
ttggggaagatcttgatcaagaacaagaagaaacatcaccacagggcctctaacggtggg
agcatccgacgcaaggatgggacagatgaacagtcttcacctttgaatgattgtccattg
tctgatggggatgtgggccagctcatgtccaatgggggtgagaagcttgcagagaggatg
gccaaagaccatgataacagcaaatctattgatcggggagatggtgagagtgatgaggag
gaggaagaggaacccattccagatccaaagaaacacaacaacactgatgagggtactgca
tatagtgaggtgaatgccacagaggagatgtccacattggtcaactacatagaaccagtc
aaattcaagtcttttgaggtggcagccaagaggaaaaagttctttgagatgtcatctttt
gtggagaccaaaggcatggacacattgaaaaattctcccaccgagtttgttgaatataat
aaaaagcaaatgagtcgcatttaccccaaagggactcgtgtggactccagcaactatatg
ccacagcttttctggaacgtgggctgccagatggtggcactaaacttccaaacccttgac
ctggcgatgcagctgaacatgggggtgtttgaatacaatggccgctgtggctatctgctg
aaaccggagttcatgagacgcactgacaaacactttgacccctttactacagacattgtg
gatggcattgtagccaatacagttaaagtcaagatcatctcaggccagtttctaaatgat
aagaaggttggtgtttatgtggaggtggacatgtttgggcttcctgcagacactaaaagg
aaatatcgaacaaaaacttcaaacaacaactctctggacccagtctgggatgatgaaacc
tttgtgttcaataaggtggtgttacctacgctagcatctctgagagtggcggtatatgaa
gaaaacggaaagtttattggtcatcgtatcttgccagtgtcagcgttgcgcccaggatat
cactacatctgtctaaagaatgaactgaaccaaccactcatgctgccttccctgcttgtg
tacactgaggtacaggactacattcccaacgagcaccaagaatatgcagaggctctaaca
aaccccatcaagcatctctctctgctggcccagagagaaagtcagctattagcacttatg
gaggatcccactgagggtgggcctacaaaacaggaggaaggagacgggactgactctagc
tgcgtgacctctgctgaccctatcttccctctgccctcatctccaacacttcctagtgta
ccaactgacttgaaccctcctccatcaggccaaaaagaagatctagtcaacaatgtcctt
aaagtaatcgagcctgagtctattgatgagcttaaacaacacaattcctacctgaagctg
ctgaagaagcaatgcaaggaatttaaggagctgagcaagaaacatctcaaaaagatgttg
gccctcagtaaggaacaaaagactctctttaatcagcagagctcggaactacagaggaaa
cgcagtcagattgagaagcgtatacgcacaagtctaaagaaaaatggatcagaagattct
gtgcatagggaattaaatgagctggatctggagctacagaaacaaatggagcagttcaga
gaggagcacatgcaaaagcttcttgtactcagacaaggacagcttcagatggagaaagaa
gtgaaacagttccacctcaaagaggccaatcagaaactgaaggatattgccatcgaatgc
caagcagcccagatcaagaaactcaaagatgtgtgtgacaaagagaaaaaggagttgcag
aagatgctggatagaaagaggctaaacagcatagttgaggccagaaaagcagaaaaggag
atagatgtgaacgagatcaatagaaaacatatccaagagtcggtcagcttaatccgtcag
ctggaagtatctcaggggaagcgtcaggagaagttgaaagcccttcataaggacatcctt
cagaaaatcgaggaggaaattcctatgaatcaggcccgtttgacccgtgactttgaggca
gagctaaagcgtttgccagaggagatttctcaatatctgcaggagcttgagagcaaaggc
tctcggaaagacagcttgatgggtcagaccaatgacggcccaaactctggccccccatcc
aactgcagcacaccaccttactcctcccccaaccacagctggagcaacatagccaatgtt
tcatccttactgctggactcctccacctcaagcacttctgccaagtccgagacagacact
acaggagtctactaa

All links

Pathway (10)   
   KEGG PATHWAY (9)   
   KEGG MODULE (1)   
Chemical substance (4)   
   KEGG COMPOUND (4)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (8)   
   KEGG ORTHOLOGY (1)   
   NCBI-Gene (1)   
   NCBI-GI (3)   
   UniGene (1)   
   OC (1)   
   ZFIN (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (7)   
   RefSeq(nuc) (1)   
   GenBank (3)   
   EMBL (3)   
Protein domain (6)   
   Pfam (6)   
All databases (40)   

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