KEGG   Danio rerio (zebrafish): 100537538Help
Entry
100537538         CDS       T01004                                 

Gene name
plcb4
Definition
(RefSeq) phospholipase C beta 4
  KO
K05858  
phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
dre  Danio rerio (zebrafish)
Pathway
Inositol phosphate metabolism
Metabolic pathways
Calcium signaling pathway
Phosphatidylinositol signaling system
Adrenergic signaling in cardiomyocytes
Vascular smooth muscle contraction
Wnt signaling pathway
Gap junction
NOD-like receptor signaling pathway
GnRH signaling pathway
Melanogenesis
AGE-RAGE signaling pathway in diabetic complications
Module
Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:dre00001]
 Metabolism
  Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    100537538 (plcb4)
 Environmental Information Processing
  Signal transduction
   04310 Wnt signaling pathway
    100537538 (plcb4)
   04020 Calcium signaling pathway
    100537538 (plcb4)
   04070 Phosphatidylinositol signaling system
    100537538 (plcb4)
 Cellular Processes
  Cellular community - eukaryotes
   04540 Gap junction
    100537538 (plcb4)
 Organismal Systems
  Immune system
   04621 NOD-like receptor signaling pathway
    100537538 (plcb4)
  Endocrine system
   04912 GnRH signaling pathway
    100537538 (plcb4)
   04916 Melanogenesis
    100537538 (plcb4)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    100537538 (plcb4)
   04270 Vascular smooth muscle contraction
    100537538 (plcb4)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    100537538 (plcb4)
Enzymes [BR:dre01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     100537538 (plcb4)
Membrane trafficking [BR:dre04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    100537538 (plcb4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    100537538 (plcb4)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-ProteinID: 
NCBI-GeneID: 
Ensembl: 
Position
17
AA seq 1271 aa AA seqDB search
MVNSSLQLKFTDVHDELTGQTGCGGKALNMEDPLVFESNCFFKVDESGFFLTWKSEGKEG
QVLEFSLINSIRDASALKDPKVLCALEASGKCESNLEDRIICICSGTDLVNLSFMYMVTQ
NPTTAKEWTDGLRSLIQNTRANNVCPMTCLRKHWMRLSFLTNVNGQIPVRSITRTFASGK
TEKGIFQALKDLGLPSGKNDEIQREIFTFDKFYSLTQKICPRTDIEVLFKKFKGDKGDYL
SVEQFVHFLNDNQRDPRLNEILFPFFNSKCAFQIIQRYEPDEKLKRKGLLSCDGFCRFLM
SDENAPVFLDRLEVYQEMDHPLSHYFINSSHNTYLTGRQFGGKSSVEIYRQVLLTGCRCV
ELDCWDGKGEDQEPIITHGKAMCTDVLFKDVIQGIKETAFLTSEYPVILSFENHCTKHQQ
YKLARYCEDIFGDLLLKQPLEDFPMEPGCPLPSPNDLKGKILIKNRRLKPEVEKKQLEDF
RKHMEAGEPSVSTNLFEDENEDETNTAELLNEAHPERIHGCLITEEENREEEVLLRHRKA
EEENVADELAVIQSYTYVAATTNIHPYLSNIINYAQAVKFTGFDEAEESSCFFLCCTVIC
LHFFCINSEKNIHHNMSSFNESVGLGYLRTNAIEFVNYNKRQMSRIYPKGGRVDSSNYMP
QIFWNAGCQMVSLNFQTPDLAMQLNQGKFEYNGSCGFLLKPDFMRRPDRMFDPFSETPVD
GVIAATCSVQVISGQFLSDKKIGTYVEVDMYGLPTDTIRKEFRTRMVMNNGLNPVYNAEA
FVFRKVILPDLAVLRVAVYDDNNKLIGQRILPLDGLQSGYRHISLRNEYNKPLPLATVFC
NIILKTYVPDGFGAIVDALSDPKKFLSICEKRTDQMRAMGIEASDIADVPSDVWKGNKKR
KTNQAGMMMKPQKDSDRPRENMPISSKEDSSVLTPQLTIDDLKQTKTFLKLIKKQQKEVN
ALKKKHAKAHAALRSSHSAQLDRTVAQHEKEKHTLEKQLHKNTSRKVSESSSLEMSRDIE
QQMKTAVMNHKSKVKDMASAQASECSEMLRWHSAEEQTVVEQHLLQQCEQLHKLLMLEQE
QQTHQLTLLHERQSKEMRTNQAKTSMESSKAISQDKSIKNKAERERRVRELNSTNTRKFL
TERKRLAMKQTKECEQLQAAQREQLERLEKHNEELSNSCYAKSQCQGRTFLSQINFTAPP
PSHDSFISGRVEVQSIMAVNYCSSFIRSQTTEQTEVHSLLCLFCPSGSLQSSGDVKACSY
YKQASKKWIEC
NT seq 3816 nt NT seq  +upstreamnt  +downstreamnt
atggtgaactcctctctgcaactcaaattcactgacgtacacgacgagctaactggacaa
actggttgtggtgggaaagccctcaacatggaggatcctttggtctttgaatcgaactgt
ttcttcaaagtagacgagtctggattcttcctgacatggaaaagcgaaggaaaggagggt
caagttttggagttttcgctgatcaacagtatacgtgatgccagtgctctaaaggaccca
aaggttctctgtgcactggaggcttcaggaaagtgtgaaagtaacctggaggacagaatc
atctgcatatgcagcggcacagatctggtcaacctgagcttcatgtacatggtcacacaa
aaccccacaactgctaaggagtggacagacggcttgcgctcattgattcagaacacaaga
gcgaataacgtgtgtccgatgacctgcctgagaaaacattggatgcggttgtcattttta
accaacgtgaatggacaaatacccgtcagaagcatcacaagaaccttcgcctctggcaaa
acagagaagggaattttccaggcgctgaaggatctcggtttacccagtggaaagaatgat
gaaatccagcgcgagatcttcacttttgacaagttctacagccttacgcagaaaatctgt
cccagaactgacattgaagtacttttcaagaaatttaagggagacaaaggtgattatttg
agtgttgagcagttcgtccactttttgaatgataatcagagagatccacgtctgaatgaa
atactgtttccgttcttcaactctaaatgtgctttccaaatcatacagagatatgagcct
gatgagaaactgaagaggaaaggtctgctgtcgtgtgatggtttctgtcggtttctgatg
tcggatgaaaacgctcctgtgtttctggatcggttggaggtttaccaggagatggatcat
ccgctatctcattacttcatcaactcctctcacaacacttacctgaccggcagacagttt
ggagggaaatcctcagtggagatttacagacaggtgctgctgaccggctgcaggtgtgtt
gagttggactgctgggatggaaaaggtgaagatcaggagcccataatcacccacggcaag
gccatgtgtacagacgtcctattcaaggatgtgattcagggaattaaagaaaccgccttc
ctgacatcagagtatcctgtgatcctgtcctttgaaaaccactgcacgaaacatcagcag
tataaactggctcgttactgcgaagacatttttggagatttgcttttgaaacagccgtta
gaggatttcccgatggagcctggatgtccactgccgtctccaaatgacctcaaaggaaaa
atcctcatcaagaacagaagactaaaacctgaagttgaaaaaaaacagctggaggacttc
aggaaacacatggaggccggagagccgagcgtctccacaaacctgtttgaagatgagaac
gaggatgagacaaacaccgctgagctgttgaatgaagctcatcccgagcggattcacgga
tgtttgatcactgaggaggagaatcgagaggaagaggtgctgctaagacacagaaaggct
gaggaggagaatgtggcagatgaactggctgtgattcagtcgtacacatatgtcgcggcc
accaccaacatccacccgtatctgtccaacatcatcaactacgcccaggctgtaaagttt
accggctttgatgaggctgaggaatcctcgtgtttctttttgtgttgtactgtaatatgt
ttacatttcttctgtataaactcagaaaaaaatatccaccacaacatgtcttccttcaat
gagtctgtcggtttgggatatttgaggacaaacgccatcgagtttgtgaactacaacaaa
cgccagatgagccgcatctaccccaaaggaggacgagtggactccagtaattacatgcca
cagatcttctggaatgccggctgccagatggtttccctgaacttccagaccccagatctg
gcaatgcagctcaaccaggggaagtttgaatataatggctcttgtgggttcctcctgaag
ccggattttatgcggagacccgatcgtatgtttgacccattctctgagacgcctgtggat
ggagtgatcgcagcaacatgcagcgtgcaggtgatctcagggcagttcctgtcagataag
aagatcggcacatatgtagaagtggacatgtatggactcccgaccgacaccattcgcaaa
gagtttcgcactcggatggtgatgaacaacggcctgaacccggtctacaacgcagaagcc
tttgtcttcaggaaggtgattctgccagacctcgcagtgctccgtgtggctgtatatgat
gataacaataagctgattggccagcggattctccctctggacggactgcagtctggttac
aggcacatctccctacgaaacgagtacaacaaacctctgcctctggccaccgtcttctgc
aatatcatcctcaaaacatacgtgcccgatggattcggagctattgtggatgctttgtct
gatcccaagaagtttttatccatctgtgagaaaagaacggaccaaatgagagccatgggc
attgaggcgtcagatattgctgatgtgccgagtgacgtctggaaggggaataagaaaaga
aaaacaaatcaggccgggatgatgatgaaaccacagaaagactcagacagacccagagaa
aatatgcccatctcctccaaagaggattcatcggttctaactccacagctgaccatcgat
gacctcaagcaaacaaagacttttctgaaactcatcaagaagcagcagaaagaagtgaac
gctttgaagaaaaagcacgcaaaggcacacgctgcactgcggagctcccacagcgctcaa
ctggacaggactgtagctcaacatgagaaagagaaacacacgctggagaagcagctccac
aaaaacaccagcaggaaagtgagtgaaagctccagccttgaaatgagcagagacattgaa
cagcaaatgaagacagcggtgatgaatcacaagtcaaaggtgaaggacatggcatccgct
caggcctcggagtgttcagagatgttgcgctggcactcagctgaagaacagacagtggtg
gagcagcatctcctccagcagtgtgagcagctccacaaactgctgatgctggagcaggag
cagcaaacacaccagctcacactcctgcacgaacgtcagagtaaagagatgcggaccaac
caagccaagacctcaatggagagcagcaaggccatcagtcaagacaaaagcataaagaac
aaggctgagcgagagcggagagttcgagagctcaacagcacgaacacaagaaagtttctt
acagaaagaaaaaggctcgccatgaaacagaccaaggagtgcgagcaactccaggcggct
cagcgggaacaactggagaggctggagaaacacaatgaggagctgtcgaactcgtgctat
gcaaaatcacaatgccaaggtaggacttttctctcacaaatcaattttacagcgcctccc
ccttcccatgattctttcatctcaggccgtgtggaagttcagtccatcatggctgtgaat
tattgttcctccttcatacgttcacagactactgagcagacagaagtccactcgctcctc
tgtttattttgcccgtcaggaagcttgcaatcatctggagatgtcaaagcgtgttcatac
tataaacaagcatctaaaaaatggattgaatgctga

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