KEGG   Danio rerio (zebrafish): 394174Help
Entry
394174            CDS       T01004                                 

Gene name
pik3cd, zgc:63473
Definition
phosphoinositide-3-kinase, catalytic, delta polypeptide (EC:2.7.1.153)
Orthology
K00922  
phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153]
Organism
dre  Danio rerio (zebrafish)
Pathway
Inositol phosphate metabolism
ErbB signaling pathway
FoxO signaling pathway
Phosphatidylinositol signaling system
mTOR signaling pathway
Apoptosis
Adrenergic signaling in cardiomyocytes
VEGF signaling pathway
Focal adhesion
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Regulation of actin cytoskeleton
Insulin signaling pathway
Progesterone-mediated oocyte maturation
Class
Metabolism; Carbohydrate metabolism; Inositol phosphate metabolism [PATH:dre00562]
Environmental Information Processing; Signal transduction; ErbB signaling pathway [PATH:dre04012]
Environmental Information Processing; Signal transduction; VEGF signaling pathway [PATH:dre04370]
Environmental Information Processing; Signal transduction; Jak-STAT signaling pathway [PATH:dre04630]
Environmental Information Processing; Signal transduction; FoxO signaling pathway [PATH:dre04068]
Environmental Information Processing; Signal transduction; Phosphatidylinositol signaling system [PATH:dre04070]
Environmental Information Processing; Signal transduction; mTOR signaling pathway [PATH:dre04150]
Cellular Processes; Cell motility; Regulation of actin cytoskeleton [PATH:dre04810]
Cellular Processes; Cell growth and death; Apoptosis [PATH:dre04210]
Cellular Processes; Cell communication; Focal adhesion [PATH:dre04510]
Organismal Systems; Immune system; Toll-like receptor signaling pathway [PATH:dre04620]
Organismal Systems; Endocrine system; Insulin signaling pathway [PATH:dre04910]
Organismal Systems; Endocrine system; Progesterone-mediated oocyte maturation [PATH:dre04914]
Organismal Systems; Circulatory system; Adrenergic signaling in cardiomyocytes [PATH:dre04261]
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif Motif
Other DBs
NCBI-GI: 
NCBI-GeneID: 
ZFIN: 
Ensembl: 
UniProt: 
Position
23
AA seq 1039 aa AA seqDB search
MPPGVYGMQEVWEMEGRQHVNIEFLLPTGIYLNFTVACSDTISTIKKMLWKNAKNEPLFS
ALSDPDAYVFTCINMTAEREELEDEQRRLCDVRPFLPILRLVAREGDRVEKLITTQINQL
IGKGHHEFDSQKNHELNEFRTKMRAFCEEHAYLRQTLPWDKWMEYNFPCDLEPCSSVTQS
GKSRSIKKIFVNVKFEGSEETFVLQQDPQDLPVVLKRNALRKKSTVFRSVKQEKPEDYSL
QVNERWEFIYGKYPLCQFKYIFTCLHGGLTPHLTMVHYSSIVKYQEEQSGLSNQVSRSRA
QSKPPPLPLKRQNTCSLWSIQEPFYIYLLQGSRVNADEGMKLVVQAGLFHGSELLCKVVT
SNEVSVCFDPVWDQKLVFDINVSDLPRMSRLCFALYGVIEKTKKRPTKKKNKRADCPLAW
VNTMVFDYKDQLKTGEFSLSTWPSVPDDKGDLLNPMGTVEKNPNIDSTAGLLIRFPNIRP
HPLYYPPIEKLNELGPNGEKVIATKEEHQKLKEIVDNKNSTEFFEDEKEPLWKLREELRL
KYPESLPKLLLITKWNKHEDVAQMVGLLQKWPELPALHALELLDYSFPDPHVRFFTIRCL
RKLPDDKLFQYLLQLVQVLKYESYLDCDLTSFLLERALANKKIGHFLFWHLRSEMHVPSV
SLRFGLILEAYCRGSIFHIKSLMKQNEALNKMKALNDFVKSASQKATRIQTTEDMKVCIK
QETYMEALSDVVSPLSPSIILCELCADKCKFMDSKMKPLWLMYKSKYDSVGIIFKNGDDL
RQDMLTLQMIQIMDILWKTEGLDLRMQPYGCLSTGNKTGLIEVVKNSDTIANIQRNNSNS
AATAAFNKDALLNWLKSKNPGDKLDQAIEEFTLSCAGYCVATYVLGIGDRHSDNIMIRES
GQLFHIDFGHFLGNFKSKFGINRERVPFILTYDFVHVIQEGRTNNSEKFERFRVCCEQAY
KILCRNGTLFVNLFALMKAAGLPELNSSKDIQYLKDSLALGKSEEEALKNFKVKFNEALR
ESWKTKVNWMMHTFAKDNR
NT seq 3120 nt NT seq  +upstreamnt  +downstreamnt
atgccgccgggggtctacggcatgcaggaagtgtgggagatggagggtcggcaacatgtc
aacattgagttcctcctccccacggggatctacctcaattttactgtagcatgcagtgac
accattagtaccatcaagaagatgctgtggaagaacgccaagaacgagcctctgttcagt
gctcttagtgatccagatgcttacgtcttcacctgcatcaacatgaccgctgagcgggaa
gagctggaagacgagcagcgccgcctgtgcgatgttcggccattcctgccaattctcaga
cttgtggcccgggaaggagaccgagtcgagaagctcatcaccacccagatcaatcagctt
atagggaaaggtcatcatgaatttgactcccaaaagaaccacgagttaaacgaattccga
acaaaaatgcgggcattttgtgaagagcatgcctacttgcgtcagacgttaccgtgggac
aagtggatggagtacaacttcccatgtgacctggagccgtgctcttcagtaacccaatct
ggcaaatcacgcagcatcaagaagatctttgtcaatgtgaagtttgagggcagtgaggag
accttcgtcctccagcaagacccacaggacctgccggtggttctgaaacgcaatgctctg
agaaagaagtccactgttttcagatcggttaagcaggagaaaccagaggactacagcctg
caggttaacgagagatgggagttcatttatggaaaatatccactctgccagttcaaatac
attttcacatgtttgcacggaggtcttaccccacacctgacgatggtgcattattcatcc
atcgtcaagtaccaggaggagcagagtggcctcagtaaccaggtgtccagaagccgtgct
cagtccaaaccaccaccgctgcctctgaaaaggcaaaacacatgttcgctgtggtcgatt
caggagcctttctatatataccttctacagggaagtcgagtaaatgcagacgaaggcatg
aagctggtggtccaggcgggcctctttcacggcagtgaactcctgtgtaaagtggtgacc
agcaatgaagtcagtgtttgctttgaccccgtatgggaccagaagctagtgttcgacatc
aatgtgagcgacctgccccgtatgagccgcctctgcttcgccctctacggcgtcattgag
aagaccaagaagcggccaaccaaaaagaaaaacaaaagagcggattgtcctttggcctgg
gtgaacacgatggtgtttgactacaaagatcagctgaagacaggagaattctccctgtcc
acgtggccatcggtcccagacgataaaggcgatttgttgaatcctatgggcactgtggag
aaaaatccaaacatcgacagcacggctggcctcctaattcgctttcccaacatcaggcca
caccccttgtactatccaccaatcgaaaagctaaatgaactgggtcccaatggtgaaaag
gtcattgctacaaaagaagagcaccagaagctgaaagagattgtggacaataaaaactcc
accgagttctttgaggatgagaaggagccgttgtggaagctgcgagaggagctgagactg
aagtacccagagagcctccccaaactcctgctcatcacaaagtggaacaaacatgaggat
gtggctcagatggtcggtttgctacagaaatggccagaattgccagccctacacgctcta
gaacttctagactacagtttcccagaccctcatgtccgcttcttcaccatccgctgcctc
aggaagctgcccgatgataagctgtttcagtatctcttgcagctggttcaggttctaaaa
tacgaatcatacctggactgcgacttgaccagtttcctgctcgaacgagctctggccaac
aagaaaataggtcacttcttgttttggcacctcaggtcagaaatgcatgtaccctcagtc
agcttgagatttggactgattctggaggcctattgtcgtgggagcatctttcacatcaag
agcttgatgaaacagaacgaggctctaaataagatgaaggctctaaatgactttgtaaag
tcggccagtcagaaggcaaccaggatacagactaccgaggatatgaaagtgtgcataaaa
caggagacatacatggaagctctctccgatgttgtttcccctcttagcccaagcatcatt
ctgtgtgaactctgtgcagacaaatgcaagttcatggactcaaagatgaaacctctatgg
ctaatgtacaagagcaaatatgattccgtgggcattattttcaaaaacggagacgatctg
aggcaggacatgttaacccttcagatgattcagataatggatattctatggaaaacagaa
ggtcttgacctcagaatgcagccctatggatgcctttcaaccggcaataaaacaggtctc
atcgaggtggtcaaaaactcagacactatcgccaacatccagagaaacaacagcaacagt
gcagccactgctgccttcaacaaggacgctcttctcaactggctcaagtccaaaaaccca
ggggataaactggatcaagccattgaggaattcaccctttcgtgtgcaggctactgtgta
gctacatatgttctgggaataggtgatcggcacagtgacaatatcatgattagggaatct
gggcagttgttccatatagatttcgggcactttttggggaacttcaagagcaaattcggg
atcaacagggaacgtgtgcctttcattctgacatatgattttgttcatgtaattcaggag
ggacggaccaacaacagtgagaaattcgaaaggtttcgcgtctgttgtgaacaagcctat
aagattctttgccggaacgggactctttttgtgaatctttttgcattgatgaaagctgca
ggtcttccggagctcaattcttccaaagacatccagtatctaaaggactctttggcactg
gggaaatcggaggaggaagcactgaagaactttaaggtcaagtttaatgaagctctacga
gagagttggaagaccaaggtgaactggatgatgcacacatttgccaaagataacagataa

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