KEGG   Danio rerio (zebrafish): 399480Help
Entry
399480            CDS       T01004                                 

Gene name
mapk3
Definition
(RefSeq) mitogen-activated protein kinase 3
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04010  MAPK signaling pathway
dre04012  ErbB signaling pathway
dre04068  FoxO signaling pathway
dre04114  Oocyte meiosis
dre04140  Autophagy - animal
dre04150  mTOR signaling pathway
dre04210  Apoptosis
dre04218  Cellular senescence
dre04261  Adrenergic signaling in cardiomyocytes
dre04270  Vascular smooth muscle contraction
dre04350  TGF-beta signaling pathway
dre04370  VEGF signaling pathway
dre04371  Apelin signaling pathway
dre04510  Focal adhesion
dre04520  Adherens junction
dre04540  Gap junction
dre04620  Toll-like receptor signaling pathway
dre04621  NOD-like receptor signaling pathway
dre04625  C-type lectin receptor signaling pathway
dre04810  Regulation of actin cytoskeleton
dre04910  Insulin signaling pathway
dre04912  GnRH signaling pathway
dre04914  Progesterone-mediated oocyte maturation
dre04916  Melanogenesis
dre04933  AGE-RAGE signaling pathway in diabetic complications
dre05132  Salmonella infection
Module
dre_M00687  MAPK (ERK1/2) signaling
Brite
KEGG Orthology (KO) [BR:dre00001]
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    399480 (mapk3)
   04012 ErbB signaling pathway
    399480 (mapk3)
   04350 TGF-beta signaling pathway
    399480 (mapk3)
   04370 VEGF signaling pathway
    399480 (mapk3)
   04371 Apelin signaling pathway
    399480 (mapk3)
   04068 FoxO signaling pathway
    399480 (mapk3)
   04150 mTOR signaling pathway
    399480 (mapk3)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    399480 (mapk3)
  Cell growth and death
   04114 Oocyte meiosis
    399480 (mapk3)
   04210 Apoptosis
    399480 (mapk3)
   04218 Cellular senescence
    399480 (mapk3)
  Cellular community - eukaryotes
   04510 Focal adhesion
    399480 (mapk3)
   04520 Adherens junction
    399480 (mapk3)
   04540 Gap junction
    399480 (mapk3)
  Cell motility
   04810 Regulation of actin cytoskeleton
    399480 (mapk3)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    399480 (mapk3)
   04621 NOD-like receptor signaling pathway
    399480 (mapk3)
   04625 C-type lectin receptor signaling pathway
    399480 (mapk3)
  Endocrine system
   04910 Insulin signaling pathway
    399480 (mapk3)
   04912 GnRH signaling pathway
    399480 (mapk3)
   04914 Progesterone-mediated oocyte maturation
    399480 (mapk3)
   04916 Melanogenesis
    399480 (mapk3)
  Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    399480 (mapk3)
   04270 Vascular smooth muscle contraction
    399480 (mapk3)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    399480 (mapk3)
  Infectious diseases
   05132 Salmonella infection
    399480 (mapk3)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     399480 (mapk3)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   399480 (mapk3)
Chromosome and associated proteins [BR:dre03036]
 Eukaryotic Type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     399480 (mapk3)
Exosome [BR:dre04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   399480 (mapk3)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr APH Haspin_kinase Kdo Choline_kinase FTA2
Motif
Other DBs
NCBI-GeneID: 399480
NCBI-ProteinID: NP_958915
ZFIN: ZDB-GENE-040121-1
Ensembl: ENSDARG00000070573
Vega: OTTDARG00000032785
UniProt: Q7ZVK8
Position
3
AA seq 392 aa AA seqDB search
MAESGSSAAAAGAAGSNSSAAGPGGAVAPGGPSGAAGSKPGLESVKGQNFDVGPRYTDLQ
YIGEGAYGMVCSAFDNVNKIRVAIKKISPFEHQTYCQRTLREIKILLRFHHENIIGINDI
LRARHIDYMRDVYIVQDLMETDLYKLLKTQQLSNDHICYFLYQILRGLKYIHSANVLHRD
LKPSNLLINTTCDLKICDFGLARIADPEHDHTGFLTEYVATRWYRAPEIMLNSKGYTKSI
DIWSVGCILAEMLSNRPIFPGKHYLDQLNHILGVLGSPSQDDLNCIINMKARNYLQSLPQ
KPKIPWNKLFPKADNKALDLLDRMLTFNPLKRINVEQALAHPYLEQYYDPSDEPVAEEPF
TFNMELDDLPKEKLKELIFEETARFQANYQGS
NT seq 1179 nt NT seq  +upstreamnt  +downstreamnt
atggcggaatcgggcagtagcgcggcggcggccggagccgcgggctcgaatagcagcgcc
gccgggcctggaggagccgtcgcacctgggggaccaagcggagcggcaggatccaagcct
ggcctggagtcggtgaagggacaaaattttgatgttggcccccgatacactgatctccag
tacatcggggagggggcctacgggatggtctgctcagcttttgataatgtgaataagatc
cgagtggccattaagaagataagtccatttgaacaccagacctactgccagcgcaccctg
agagagatcaaaatcctcctgcggttccatcatgagaacatcatcgggatcaatgacatc
ctgagagctcgccacattgattatatgagggatgtctatatcgtacaggacctgatggag
accgacctttataaactgctgaagacacagcaactcagcaacgaccatatctgctacttt
ctgtatcagatcctgcgagggctgaagtacattcactctgccaatgtgctgcacagagac
ctgaagccctcaaaccttctcatcaacaccacctgtgacctcaagatctgtgattttggg
ttggcgaggatagctgaccctgaacatgaccacactggattcctcacagagtatgtggct
actcgctggtaccgtgcccctgagatcatgcttaactccaagggctacaccaagtccatt
gatatttggtctgtgggatgcatcctggctgagatgttgtccaacagacccatcttccct
gggaagcactatctggaccagctcaaccatatattgggtgttctgggctccccctctcaa
gatgatctgaactgcatcatcaacatgaaggccaggaactacctccagtctttaccacag
aaacccaagatcccatggaacaagctgtttcccaaagcagacaacaaagctttggattta
ttggatcgcatgttaacctttaaccctcttaaacgtataaatgtggagcaagcactggcc
cacccctacctggagcagtactatgacccatctgatgagccggtagctgaggaacccttc
actttcaacatggagctggacgaccttcctaaagagaagctgaaagagctcatctttgag
gagacggcacgcttccaggccaattaccagggctcctga

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