KEGG   Danio rerio (zebrafish): 559281Help
Entry
559281            CDS       T01004                                 

Gene name
irs1
Definition
(RefSeq) insulin receptor substrate 1
  KO
K16172  
insulin receptor substrate 1
Organism
dre  Danio rerio (zebrafish)
Pathway
FoxO signaling pathway
Autophagy - animal
mTOR signaling pathway
Insulin signaling pathway
Adipocytokine signaling pathway
Module
PI3K-Akt signaling
Brite
KEGG Orthology (KO) [BR:dre00001]
 Environmental Information Processing
  Signal transduction
   04068 FoxO signaling pathway
    559281 (irs1)
   04150 mTOR signaling pathway
    559281 (irs1)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    559281 (irs1)
 Organismal Systems
  Endocrine system
   04910 Insulin signaling pathway
    559281 (irs1)
   04920 Adipocytokine signaling pathway
    559281 (irs1)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: 
Motif
Other DBs
NCBI-GeneID: 
NCBI-ProteinID: 
ZFIN: 
Ensembl: 
Vega: 
UniProt: 
Position
15
AA seq 1099 aa AA seqDB search
MASPTTEQGCFSDVKKVGYLRKPKSMHKRFFVLRAASASGPSRLEYYENEKKWRHKSGAP
KRSIPLESCFNINKRADSKNKHLVALYTKDEYFAIAADSEIEQESWYEALVDLHNRGKVH
ETAPGRGVGEDNYGEATPGPAFKEVWQVILKPKGLGHTKNLIGVYRLCLTNKTISFVKLN
SDAAAVVLQLMNIRRCGHSENFFFIEVGRSAVTGPGEFWMQVDDSVVAQNMHETILEAMK
AMSEEFRPRSKSQSSSNCSNPISVPVRRHHHNNPPPSQVGLGRRSRAESVTATSPVRPGK
HSHSFRVRASSDGEGTMSRPASVDGSPSSPSNARPQSQRHRGGSRLHPPLNHSRSIPTPT
SRCSPSAISPISLSSSSTSGHGSTSDCLFPRRSSASISGSPSDGGFISSDEYGSSPCDFR
SSFRSVTPDSLGHTPPAREEEINNYICMAKPGSLPGAGSQSRSQSRGTPSRLEEPELEKC
FRKRTHSSGASPPTPCHQKTPSQSPAASLEEYTVMMPTYPRSRSASSSSSTYRHSFMPTH
SYPEEGTDASQAKDERGPDHKDDGYMPMLPGVAPATPTTKSSDYMPMSPKSVSAPQQIIN
PRQHSHVDSNGYMMMSPSGSCSPDGTTNYGKIWTNGINPKLSVESMEGKVSSCGDYINMS
PASCSTTSTPPDCFFNPVEDPPRPMYAYYSLPRSFKHANRKQDQSPLRVSLGSSRLAYAD
SSSSSASSDSLGGQSNSQQSAVKPKRSEGNGRLTRPTRLSLDASKASTLPRTRESPFPPE
PKSPGEYVNIEFNDKAFSASLASLFPPVYSVSDAEAPSDLSSSEYMNMQLGSQARRLCSE
LQTSSSSSDYAIITPSNSVSSPPLPCESICERDYISMQLASCTGFPDTQLMLMTEALPDA
DAPPCSVSPNHDVTTLSGAPGRPALISPLSGLSAFTRVNSTSGRNQGAKVIRADPQGRRR
HSSETFASTATRGSVDTSSTCQSGDVKRHSSASFENVWLRPDQASAASTAPSASTVTNGR
RETASGQIPTLTNHDQNGLNYIDLDLMQNGEQHVPDWNAFQSRPVELGAVEGIEELSAYA
SINFQKSDETRGNLTHREE
NT seq 3300 nt NT seq  +upstreamnt  +downstreamnt
atggcaagcccgactacggagcaaggatgtttttcagacgtgaaaaaggtgggttattta
aggaaacccaaaagcatgcacaaaaggttttttgtactgagggcggcgagcgcctccgga
ccgtcccgactggagtactatgaaaacgagaagaagtggagacacaagtctggagcgccg
aaaagatccattccgctggagagctgctttaacatcaacaaaagagcggattcaaaaaac
aaacatctcgtcgcgctttataccaaggatgagtactttgctatcgctgctgacagcgag
atcgagcaagagtcatggtatgaagccctggttgatctccataacagaggtaaggtccac
gaaactgccccgggccgtggagttggcgaggataattacggggaagccacgccgggacct
gcctttaaagaggtttggcaagttatattgaaaccaaagggtctgggtcacacaaagaac
ttgattggagtttacagattatgcctcaccaataagactatcagctttgtgaaactgaat
tcggatgcagcagctgtggttttgcagttgatgaacattaggagatgtggtcactctgaa
aatttcttttttattgaagtcggccgatctgctgtgacaggccccggggagttttggatg
caagtggatgactctgttgtggctcagaacatgcatgaaactatattagaagccatgaaa
gccatgagtgaggagttcagaccccgcagcaaaagccagtcatcttctaactgctcaaac
cccatctcagtgcctgtcaggcggcatcatcacaataatcctccccctagtcaagttggc
ttaggcaggcgctctcgggcggagagtgtgacggccacttctcctgttaggcctggcaaa
cacagccattcgtttagagtgagagcatctagtgatggagagggcaccatgtccaggccg
gcatctgtggacgggagtccaagcagcccgagcaatgcccgacctcaatcgcaacggcac
agagggggatccagacttcacccgccactcaatcacagcagatcaatacccacgcccacc
tcacggtgctccccctcagccatcagccccatcagcctgtcctccagcagcacgagcggg
catggctccacatctgactgcctctttccacgtcgctctagtgcctcgatatctggatca
cccagcgatggcggattcatctcctcagatgaatatggatccagcccctgtgactttcga
agctcgtttcgtagcgtgactccagactcgcttggccacacaccacctgccagggaggaa
gagataaacaactacatctgcatggcaaagcccggttcacttcctggtgccgggagccag
tcacgaagccaatctagaggaacaccgtcaagactagaggagcctgagttggaaaaatgt
tttcggaaaagaactcattcttctggtgcttcgccgccaactccatgccatcagaaaact
ccctcacaatcgcctgctgcatctttagaggaatacactgtgatgatgcctacataccca
cgaagccgctctgcatcatcgtcatcatcaacatataggcactcattcatgccaacacat
tcatacccagaggaaggtacagatgcatcacaagcaaaagatgaaagggggccagatcac
aaagatgacggctatatgcccatgctgccaggcgttgcgcctgcaacccctacaaccaaa
agcagtgactacatgcccatgagtccaaaaagtgtgtctgcaccacagcaaattatcaac
cccaggcaacactcgcatgtcgactccaatggttacatgatgatgtcaccaagtggcagc
tgctctccagatggcacaacaaactatggcaagatctggacgaatggcatcaaccctaag
ctctccgtagagagtatggaaggtaaagtgtcgtcatgtggagattacataaacatgtct
ccagctagttgctcaacaacaagtacgcctccagactgctttttcaaccctgtggaagat
cctcccaggcctatgtatgcttactactctttgccccgctcattcaaacatgctaacagg
aagcaggatcagagcccgcttcgagtgtcactgggctcgagtcgattagcatacgctgac
tcctcttcatcttcagcaagcagtgacagcttgggtggtcaaagcaattcccagcagtct
gctgtcaaacccaaaaggtcagagggcaacggtaggctgacacgtccaacacggctgtca
ctggacgccagcaaagcaagtactcttccacgcacacgtgagagccccttccctcctgag
cctaaaagtcctggggagtatgtcaacattgagttcaacgacaaggcattttcagcgagc
ttagcatcgctgttcccacctgtttattcagtaagtgatgctgaggccccgtcggatctt
tcatcatctgagtacatgaacatgcagctgggatcccaggccagacggctgtgctccgaa
ttgcagacttcctcttccagttcagattatgccataatcacaccgtcaaactctgtatcc
tcgcctccactgccatgtgagagcatatgtgaacgtgactacatcagcatgcagttagca
tcctgcactggctttcctgacacacaattgatgctaatgaccgaggccctgccagatgca
gatgcccctccttgttctgtatcacccaatcatgacgtgacgacattaagcggcgctcct
ggaagaccagctctgattagccctttatcaggtctgagtgcattcacacgggttaactcc
acttccggacgaaaccagggcgctaaagtaatacgtgctgacccacagggtcgacggcgg
cacagttcagagacttttgcatccacagcgaccagagggtcagtcgacacatcgagcacc
tgtcaatcaggggatgtaaagcgccacagctccgcctccttcgagaatgtgtggttgaga
cctgatcaggcctctgctgcttctaccgctccatctgcatcgacagtaaccaacggacga
agggaaaccgcttcaggccaaattcccacattaacaaaccatgaccagaacggcctgaac
tacattgatctggatctaatgcagaatggagagcaacatgttcctgattggaatgctttc
cagtctcggccggtggagctgggagctgttgaaggtatagaagagctcagtgcctatgcc
agtataaacttccagaaatcagatgagaccagagggaatctcacacacagagaagaatga

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