KEGG   Danio rerio (zebrafish): 562720Help
Entry
562720            CDS       T01004                                 

Gene name
mapk8a
Definition
(RefSeq) mitogen-activated protein kinase 8
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
dre  Danio rerio (zebrafish)
Pathway
dre04010  MAPK signaling pathway
dre04012  ErbB signaling pathway
dre04068  FoxO signaling pathway
dre04137  Mitophagy - animal
dre04140  Autophagy - animal
dre04141  Protein processing in endoplasmic reticulum
dre04210  Apoptosis
dre04217  Necroptosis
dre04310  Wnt signaling pathway
dre04510  Focal adhesion
dre04530  Tight junction
dre04620  Toll-like receptor signaling pathway
dre04621  NOD-like receptor signaling pathway
dre04622  RIG-I-like receptor signaling pathway
dre04625  C-type lectin receptor signaling pathway
dre04910  Insulin signaling pathway
dre04912  GnRH signaling pathway
dre04914  Progesterone-mediated oocyte maturation
dre04920  Adipocytokine signaling pathway
dre04933  AGE-RAGE signaling pathway in diabetic complications
dre05132  Salmonella infection
dre05168  Herpes simplex infection
Module
dre_M00688  MAPK (JNK) signaling
Brite
KEGG Orthology (KO) [BR:dre00001]
 Genetic Information Processing
  Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    562720 (mapk8a)
 Environmental Information Processing
  Signal transduction
   04010 MAPK signaling pathway
    562720 (mapk8a)
   04012 ErbB signaling pathway
    562720 (mapk8a)
   04310 Wnt signaling pathway
    562720 (mapk8a)
   04068 FoxO signaling pathway
    562720 (mapk8a)
 Cellular Processes
  Transport and catabolism
   04140 Autophagy - animal
    562720 (mapk8a)
   04137 Mitophagy - animal
    562720 (mapk8a)
  Cell growth and death
   04210 Apoptosis
    562720 (mapk8a)
   04217 Necroptosis
    562720 (mapk8a)
  Cellular community - eukaryotes
   04510 Focal adhesion
    562720 (mapk8a)
   04530 Tight junction
    562720 (mapk8a)
 Organismal Systems
  Immune system
   04620 Toll-like receptor signaling pathway
    562720 (mapk8a)
   04621 NOD-like receptor signaling pathway
    562720 (mapk8a)
   04622 RIG-I-like receptor signaling pathway
    562720 (mapk8a)
   04625 C-type lectin receptor signaling pathway
    562720 (mapk8a)
  Endocrine system
   04910 Insulin signaling pathway
    562720 (mapk8a)
   04920 Adipocytokine signaling pathway
    562720 (mapk8a)
   04912 GnRH signaling pathway
    562720 (mapk8a)
   04914 Progesterone-mediated oocyte maturation
    562720 (mapk8a)
 Human Diseases
  Endocrine and metabolic diseases
   04933 AGE-RAGE signaling pathway in diabetic complications
    562720 (mapk8a)
  Infectious diseases
   05132 Salmonella infection
    562720 (mapk8a)
   05168 Herpes simplex infection
    562720 (mapk8a)
Enzymes [BR:dre01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     562720 (mapk8a)
Protein kinases [BR:dre01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   562720 (mapk8a)
BRITE hierarchy
SSDB OrthologParalogGFIT
Motif
Pfam: Pkinase Pkinase_Tyr Kdo APH RIO1 Kinase-like FTA2
Motif
Other DBs
NCBI-GeneID: 562720
NCBI-ProteinID: NP_001103859
ZFIN: ZDB-GENE-080218-17
Ensembl: ENSDARG00000031888
Vega: OTTDARG00000029752
UniProt: A8WG58
Position
13
AA seq 427 aa AA seqDB search
MNKNKREKEFYSVDVGDSTFTVLKRYQNLRPIGSGAQGIVCSAYDNNLERNVAIKKLSRP
FQNQTHAKRAYRELVLMKCVNHKNIIGLLNVFTPQKTLEEFQDVYLVMELMDANLCQVIQ
MELDHERLSYLLYQMLCGIKHLHAAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAATGL
LMTPYVVTRYYRAPEVILGMGYQANVDVWSVGCIMAEMVRGSVLFPGSDHIDQWNKVIEQ
LGTPTQEFLLKLNQSVRTYVENRPRYTGYSFEKLFPDVLFPADSEHSKLKASQARDLLSK
MLVIDASKRISVDEALQHPYINVWYDPAEVEAPSPLITDKQLDEREHTVEEWKELIYKEV
LDWEERMKNGVIRGQPSPLGAAVINGSPQPSSSSSINDVSSMSTEPTVASDTDSSLEASA
GPLSCCR
NT seq 1284 nt NT seq  +upstreamnt  +downstreamnt
atgaacaaaaataagcgagagaaagaattctacagtgtagatgtgggggattcgacattc
acagtgttgaagcgctatcagaatctaagacccattggctcgggtgctcagggaatagtc
tgctcagcgtatgacaacaacctcgagcgaaacgtggctataaagaaactcagccggcct
tttcaaaatcaaactcatgccaaacgtgcgtacagagagctggtgctcatgaaatgtgtc
aaccataaaaatataataggcctcttaaatgtttttacaccgcaaaaaacattagaagaa
ttccaagatgtttacctagtaatggagctgatggatgcgaacctctgccaagtcattcag
atggagctggaccacgagcggctgtcctatctgctgtaccagatgctgtgtggaataaaa
cacctccacgcggcggggatcatccacagggacctgaaacccagtaacatcgtggtaaag
tcagactgtaccctgaagatcctggatttcggtctggcgcggacagcagctacaggtctg
ctgatgacaccatatgtggtgacccgttactacagagcccctgaagtcatcctgggaatg
ggatatcaagccaatgtggatgtgtggtctgtcggctgtatcatggctgaaatggtcaga
ggtagtgtattatttccgggttcagatcatattgatcagtggaataaagtaatagagcag
ctgggaacgccaactcaggagttcttgttgaaactcaaccagtctgtgcggacctatgtg
gagaacaggccccggtacactggatatagctttgagaagctgtttcctgatgtcctgttc
cctgctgattcagaacacagcaaactaaaagcgagtcaggcgcgggacctgctgtctaaa
atgctggtgattgatgcatcaaaacgaatctcggtggatgaggctttgcagcacccctac
attaacgtgtggtacgacccggctgaagtggaagcgccttctcctctgatcacagacaaa
cagctcgatgagagggaacacacagtggaagagtggaaagaactgatctataaagaagtg
ctggattgggaagaacggatgaagaacggtgttattcgaggtcagccctcccccctaggt
gcagcagtgatcaacggctcaccccagccctcatcctcatcctccatcaacgacgtgtcc
tccatgtccacagagcccaccgtggcctcagacacagacagcagcttagaggcctcggcg
ggacccctgagctgctgcagatga

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