| Entry |
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| Name |
Ketoprofen (JP16/USP/INN);
Orudis (TN)
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| Product |
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| Generic |
KETOPROFEN (Bryant Ranch Prepack), KETOPROFEN (Bryant Ranch Prepack), KETOPROFEN (H.J. Harkins Company), KETOPROFEN (Mylan Pharmaceuticals), KETOPROFEN (PD-Rx Pharmaceuticals), KETOPROFEN (PD-Rx Pharmaceuticals), KETOPROFEN (Physicians Total Care), KETOPROFEN (Preferred Pharmaceuticals), KETOPROFEN (Rebel Distributors Corp), KETOPROFEN (Rebel Distributors Corp), KETOPROFEN (RedPharm Drug), KETOPROFEN (STAT RX USA LLC), KETOPROFEN (Teva Pharmaceuticals USA) |
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| Formula |
C16H14O3
|
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| Exact mass |
254.0943
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| Mol weight |
254.2806
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| Structure |
     |
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| Activity |
Anti-inflammatory
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Target |
cyclooxygenase-1 (COX-1) inhibitor [HSA: 5742] [KO: K00509]; cyclooxygenase-2 (COX-2) inhibitor [HSA: 5743] [KO: K11987] |
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| Pathway |
|
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| Interaction |
Transporter inhibition: OAT2 [HSA: 10864]
 |
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| Structure map |
| Cyclooxygenase inhibitors |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
114 Antipyretics and analgesics, anti-inflammatory agents
1149 Others
D00132 Ketoprofen (JP16/USP/INN)
2 Agents affecting individual organs
26 Epidermides
264 Analgesics, anti-itchings, astringents, anti-inflammatory agents
2649 Others
D00132 Ketoprofen (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
M MUSCULO-SKELETAL SYSTEM
M01 ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS
M01A ANTIINFLAMMATORY AND ANTIRHEUMATIC PRODUCTS, NON-STEROIDS
M01AE Propionic acid derivatives
M01AE03 Ketoprofen
D00132 Ketoprofen (JP16/USP/INN)
M02 TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02A TOPICAL PRODUCTS FOR JOINT AND MUSCULAR PAIN
M02AA Antiinflammatory preparations, non-steroids for topical use
M02AA10 Ketoprofen
D00132 Ketoprofen (JP16/USP/INN)
USP drug classification [BR:br08302]
Analgesics
Nonsteroidal Anti-inflammatory Drugs
Ketoprofen
D00132 Ketoprofen (JP16/USP/INN)
Anti-inflammatory Agents
Nonsteroidal Anti-inflammatory Drugs
Ketoprofen
D00132 Ketoprofen (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
Enzymes
Oxidoreductases
cyclooxygenase-1 (COX-1) [HSA:5742] [KO:K00509]
Ketoprofen [ATC:M02AA10]
D00132 Ketoprofen (JP16/USP/INN)
cyclooxygenase-2 (COX-2) [HSA:5743] [KO:K11987]
Ketoprofen [ATC:M02AA10]
D00132 Ketoprofen (JP16/USP/INN)
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| Other DBs |
CAS: 22071-15-4 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 19
1 C8x C 6.4400 -15.7500
2 C8x C 6.4400 -17.1500
3 C8x C 7.6524 -17.8500
4 C8x C 8.8649 -17.1500
5 C8y C 8.8649 -15.7500
6 C8x C 7.6524 -15.0500
7 C8x C 11.2897 -17.1500
8 C8y C 11.2897 -15.7500
9 C5a C 10.0773 -15.0500
10 C8x C 12.5022 -17.8500
11 C8x C 13.7146 -17.1500
12 C8y C 13.7146 -15.7500
13 C8x C 12.5022 -15.0500
14 O5a O 10.0773 -13.6500
15 C1c C 14.9311 -15.0477
16 C6a C 16.1286 -15.7392
17 C1a C 14.9311 -13.6502
18 O6a O 17.3149 -15.0543
19 O6a O 16.1287 -17.1497
BOND 20
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 1
8 8 9 1
9 5 9 1
10 7 10 2
11 10 11 1
12 11 12 2
13 12 13 1
14 8 13 2
15 9 14 2
16 12 15 1
17 15 16 1
18 15 17 1
19 16 18 1
20 16 19 2
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