KEGG   DRUG: D00224Help
Entry
D00224                      Drug                                   

Name
Allopurinol (JP16/USP/INN);
Zyloprim (TN)
Product
  Generic
ALLOPURINOL (A-S Medication Solutions LLC), ALLOPURINOL (Accord Healthcare), ALLOPURINOL (American Health Packaging), ALLOPURINOL (Aphena Pharma Solutions - Tennessee), ALLOPURINOL (Cardinal Health), ALLOPURINOL (Cardinal Health), ALLOPURINOL (Cardinal Health), ALLOPURINOL (Clinical Solutions Wholesale), ALLOPURINOL (Dr. Reddy's Laboratories Limited), ALLOPURINOL (Ipca Laboratories Limited), ALLOPURINOL (Lake Erie Medical DBA Quality Care Products LLC), ALLOPURINOL (Lake Erie Medical DBA Quality Care Products LLC), ALLOPURINOL (Lake Erie Medical DBA Quality Care Products LLC), ALLOPURINOL (Major Pharmaceuticals), ALLOPURINOL (Major Pharmaceuticals), ALLOPURINOL (McKesson Contract Packaging), ALLOPURINOL (Mutual Pharmaceutical), ALLOPURINOL (Mylan Institutional), ALLOPURINOL (Mylan Pharmaceuticals), ALLOPURINOL (NCS HealthCare of KY), ALLOPURINOL (Northstar RxLLC), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (PD-Rx Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Preferred Pharmaceuticals), ALLOPURINOL (Qualitest Pharmaceuticals), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (REMEDYREPACK), ALLOPURINOL (Ranbaxy Pharmaceuticals), ALLOPURINOL (Rebel Distributors Corp.), ALLOPURINOL (STAT Rx USA LLC), ALLOPURINOL (St Marys Medical Park Pharmacy), ALLOPURINOL (St Marys Medical Park Pharmacy), ALLOPURINOL (Unit Dose Services), ALLOPURINOL (Unit Dose Services)
Formula
C5H4N4O
Exact mass
136.0385
Mol weight
136.1115
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Uricostatic, Xanthine oxidase inhibitor
Remark
Therapeutic category: 
ATC code: 
Drug group: 
Target
xanthine dehydrogenase/oxidase inhibitor [HSA:7498] [KO:K00106]
  Pathway
hsa00230  Purine metabolism  
 
Interaction
Drug interaction
Other map
Bile secretion
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 M MUSCULO-SKELETAL SYSTEM
  M04 ANTIGOUT PREPARATIONS
   M04A ANTIGOUT PREPARATIONS
    M04AA Preparations inhibiting uric acid production
     M04AA01 Allopurinol
      D00224  Allopurinol (JP16/USP/INN)
USP drug classification [BR:br08302]
 Antigout Agents
  Allopurinol
   D00224  Allopurinol (JP16/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 3  Agents affecting metabolism
  39  Other agents affecting metabolism
   394  Gout preparations
    3943  Allopurinols
     D00224  Allopurinol (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases
   xanthine dehydrogenase/oxidase
    Allopurinol
     D00224  Allopurinol (JP16/USP/INN)
Cytochrome P450 interactions [BR:br08309]
 Inhbitors
  CYP1A2
   Allopurinol
    D00224  Allopurinol (JP16/USP/INN)
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00224  Allopurinol
  D00224  Allopurinol tablets
BRITE hierarchy
Other DBs
CAS: 
315-30-0
PubChem: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        10
            1   C8y C    21.1213  -17.3585
            2   C8y C    21.1213  -18.7576
            3   C8y C    22.3388  -16.6560
            4   N4x N    19.7865  -16.9312
            5   N5x N    22.3388  -19.4601
            6   C8x C    19.7924  -19.1966
            7   N5x N    23.5446  -17.3585
            8   O1a O    22.3388  -15.2571
            9   N5x N    18.9671  -18.0609
            10  C8x C    23.5446  -18.7576
BOND        11
            1     1   2 2
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 2
            7     3   8 1
            8     4   9 1
            9     5  10 2
            10    6   9 2
            11    7  10 1

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