| Entry |
|
|---|
| Name |
Theophylline (JP16);
Elixophyllin (TN);
Quibron-t (TN);
Theo-24 (TN);
Theodur G (TN);
Theolair (TN);
Uniphyl (TN)
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| Product |
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| Generic |
THEOPHYLLINE (Bryant Ranch Prepack), THEOPHYLLINE (Bryant Ranch Prepack), THEOPHYLLINE (Cardinal Health), THEOPHYLLINE (Glenmark Generics), THEOPHYLLINE (Heritage Pharmaceuticals), THEOPHYLLINE (Major Pharmaceuticals), THEOPHYLLINE (Nostrum Laboratories), THEOPHYLLINE(ANHYDROUS) (PACK Pharmaceuticals), THEOPHYLLINE (Physicians Total Care), THEOPHYLLINE (Pliva), THEOPHYLLINE (REMEDYREPACK), THEOPHYLLINE (REMEDYREPACK), THEOPHYLLINE (Rhodes Pharmaceuticals L.P.), THEOPHYLLINE (Silarx Pharmaceuticals), THEOPHYLLINE (State of Florida DOH Central Pharmacy), THEOPHYLLINE (Tris Pharma), ELIXOPHYLLIN (Atlantic Biologicals Corps), ELIXOPHYLLIN (Caraco Pharma), THEOPHYLLINE (Pharmaceutical Associates), UNIPHYL (Purdue Pharmaceutical Products LP), THEO-24 (UCB), THEO-24 (Cardinal Health), THEOPHYLLINE EXTENDED RELEASE (NCS HealthCare of KY), THEOPHYLLINE EXTENDED RELEASE (NCS HealthCare of KY) |
|---|
| Formula |
C7H8N4O2
|
|---|
| Exact mass |
180.0647
|
|---|
| Mol weight |
180.164
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| Structure |
     |
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| Activity |
|
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| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Comment |
Xanthines
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| Target |
|
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| Pathway |
|
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| Metabolism |
Enzyme: CYP1A2 [HSA: 1544], CYP2E1 [HSA: 1571]
|
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| Interaction |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
22 Respiratory organ agents
225 Bronchodilators
2251 Xanthines
D00371 Theophylline (JP16)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
R RESPIRATORY SYSTEM
R03 DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03D OTHER SYSTEMIC DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES
R03DA Xanthines
R03DA04 Theophylline
D00371 Theophylline (JP16)
USP drug classification [BR:br08302]
Respiratory Tract Agents
Bronchodilators, Phosphodiesterase Inhibitors (Xanthines)
Theophylline
D00371 Theophylline (JP16)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adenosine
adenosine A1 receptor [HSA:134] [KO:K04265]
Theophylline [ATC:R03DA04]
D00371 Theophylline (JP16)
adenosine A2a receptor [HSA:135] [KO:K04266]
Theophylline [ATC:R03DA04]
D00371 Theophylline (JP16)
Enzymes
Hydrolases
phosphodiesterase (PDE) [HSA:10846 27115 50940 5136 5137 5138 5139 5140 5141 5142 5143 5144 5150 5151 5153 8622] [KO:K01120 K13296 K13298 K13755]
Theophylline [ATC:R03DA04]
D00371 Theophylline (JP16)
 |
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| Other DBs |
CAS: 58-55-9 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 13
1 C8y C 24.1848 -17.2082
2 C8y C 24.1848 -18.6318
3 C8y C 25.3867 -16.5023
4 N4x N 22.8837 -16.7764
5 N4y N 25.3867 -19.3144
6 N5x N 22.8837 -19.0636
7 N4y N 26.6061 -17.2374
8 O5x O 25.3867 -15.1253
9 C8x C 22.0669 -17.9317
10 C8y C 26.6061 -18.5794
11 C1a C 25.3867 -20.7440
12 C1a C 27.8547 -16.5606
13 O5x O 27.8547 -19.2794
BOND 14
1 1 2 2
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 2
8 4 9 1
9 5 10 1
10 5 11 1
11 7 12 1
12 10 13 2
13 6 9 2
14 7 10 1
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