| Entry |
|
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| Name |
Flutamide (JP16/USP/INN);
Eulexin (TN)
|
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| Product |
|
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| Generic |
|
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| Formula |
C11H11F3N2O3
|
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| Exact mass |
276.0722
|
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| Mol weight |
276.2119
|
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| Structure |
     |
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| Activity |
|
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| Remark |
Same as: Therapeutic category: ATC code: |
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| Target |
androgen receptor antagonist [HSA: 367] [KO: K08557] |
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| Pathway |
|
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| Interaction |
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| Structure map |
| Antineoplastics - hormones | | Progesterone, androgen and estrogen receptor agonists/antagonists |
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
4 Agents affecting cellular function
42 Antineoplastics
429 Miscellaneous
4291 Other Antitumors
D00586 Flutamide (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
L ANTINEOPLASTIC AND IMMUNOMODULATING AGENTS
L02 ENDOCRINE THERAPY
L02B HORMONE ANTAGONISTS AND RELATED AGENTS
L02BB Anti-androgens
L02BB01 Flutamide
D00586 Flutamide (JP16/USP/INN)
USP drug classification [BR:br08302]
Hormonal Agents
Hormonal Agents, Suppressant (Sex Hormones/ Modifiers)
Antiandrogens
Flutamide
D00586 Flutamide (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
androgen receptor [HSA:367] [KO:K08557]
Flutamide [ATC:L02BB01]
D00586 Flutamide (JP16/USP/INN)
Antineoplastics [BR:br08308]
Hormones and hormone antagonist
Androgen antagonist
Flutamide [ATC:L02BB01]
D00586 Flutamide (JP16/USP/INN)
 |
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| Other DBs |
CAS: 13311-84-7 PubChem: DrugBank: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 19
1 C8x C 37.5200 -20.3000
2 C8y C 38.7100 -19.6700
3 C8x C 36.2600 -19.6700
4 C8y C 38.7100 -18.2700
5 N2b N 39.9000 -20.3000 #+
6 C8y C 36.2600 -18.2700
7 C8x C 37.5200 -17.5700
8 O3a O 39.9000 -21.7000
9 O3a O 41.1600 -19.6000 #-
10 N1b N 35.0700 -17.5700
11 C5a C 33.8800 -18.2700
12 C1c C 32.6900 -17.5700
13 O5a O 33.8800 -19.6000
14 C1a C 31.4300 -18.2700
15 C1a C 32.6900 -16.1700
16 C1d C 39.9253 -17.5749
17 X F 41.1377 -16.8749
18 X F 39.2253 -16.3625
19 X F 40.6253 -18.7874
BOND 19
1 1 2 2
2 1 3 1
3 2 4 1
4 2 5 1
5 3 6 2
6 4 7 2
7 5 8 2
8 5 9 1
9 6 10 1
10 10 11 1
11 11 12 1
12 11 13 2
13 12 14 1
14 12 15 1
15 6 7 1
16 4 16 1
17 16 17 1
18 16 18 1
19 16 19 1
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