KEGG   DRUG: D07715Help
Entry
D07715                      Drug                                   

Name
Clobetasol (INN);
Clobecort Amex (TN)
Formula
C22H28ClFO4
Exact mass
410.166
Mol weight
410.9067
Structure
Mol fileKCF fileDB searchJmolKegDraw
Activity
Adrenal cortex hormone, glucocorticoid;
Dermatological
Remark
ATC code: 
Drug group: 
Target
glucocorticoid receptor agonist [HSA:2908] [KO:K05771]
  Pathway
hsa04080  Neuroactive ligand-receptor interaction  
 
Interaction
Drug interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 D DERMATOLOGICALS
  D07 CORTICOSTEROIDS, DERMATOLOGICAL PREPARATIONS
   D07A CORTICOSTEROIDS, PLAIN
    D07AD Corticosteroids, very potent (group IV)
     D07AD01 Clobetasol
      D07715  Clobetasol (INN)
USP drug classification [BR:br08302]
 Hormonal Agents, Stimulant/Replacement/Modifying (Adrenal)
  Clobetasol
   D07715  Clobetasol (INN)
Target-based classification of drugs [BR:br08310]
 Nuclear receptors
  Estrogen like receptors
   3-Ketosteroid receptor
    glucocorticoid receptor
     Clobetasol
      D07715  Clobetasol (INN)
BRITE hierarchy
Other DBs
CAS: 
25122-41-2
PubChem: 
DrugBank: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        28
            1   C1z C    25.6900  -17.2200
            2   C1z C    24.5000  -17.9200
            3   C1y C    26.8800  -17.9200
            4   O1a O    26.8800  -16.5900
            5   C5a C    25.6900  -15.8900
            6   C1y C    24.5000  -19.2500
            7   C1x C    23.3800  -17.2200
            8   C1a C    24.5000  -16.5900
            9   C1x C    26.8800  -19.2500
            10  C1b C    26.8800  -15.1900
            11  O5a O    24.5000  -15.1900
            12  C1y C    23.3800  -19.9500
            13  C1y C    22.1900  -17.9200
            14  X   Cl   26.8800  -13.8600
            15  C1z C    22.1900  -19.2500
            16  C1x C    23.3800  -21.2800
            17  O1a O    21.0000  -17.2200
            18  C1z C    21.0000  -19.9500
            19  X   F    22.1900  -20.6500
            20  C1x C    22.1900  -21.9800
            21  C2y C    21.0000  -21.2800
            22  C2x C    19.8100  -19.2500
            23  C1a C    21.0000  -18.6200
            24  C2x C    19.8100  -21.9800
            25  C2x C    18.6900  -19.9500
            26  C5x C    18.6900  -21.2800
            27  O5x O    17.5000  -21.9800
            28  C1a C    28.2100  -17.9200
BOND        31
            1     1   5 1 #Up
            2     2   6 1
            3     2   7 1
            4     2   8 1 #Up
            5     3   9 1
            6     5  10 1
            7     5  11 2
            8     6  12 1
            9     7  13 1
            10   10  14 1
            11   12  15 1
            12   12  16 1
            13   13  17 1 #Up
            14   15  18 1
            15   15  19 1 #Down
            16   16  20 1
            17   18  21 1
            18   18  22 1
            19   18  23 1 #Up
            20   21  24 2
            21   22  25 2
            22   24  26 1
            23   26  27 2
            24    6   9 1
            25   13  15 1
            26   20  21 1
            27   25  26 1
            28    3  28 1 #Up
            29    1   2 1
            30    1   3 1
            31    1   4 1 #Down

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