| Entry |
|
|---|
| Name |
Progesterone (JP16/USP/INN);
Crinone (TN);
Prometrium (TN)
|
|---|
| Product |
|
|---|
| Generic |
|
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| Formula |
C21H30O2
|
|---|
| Exact mass |
314.2246
|
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| Mol weight |
314.4617
|
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| Structure |
     |
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| Activity |
Progestin
|
|---|
| Remark |
Same as: Therapeutic category: ATC code: |
|---|
| Target |
progesterone receptor agonist [HSA: 5241] [KO: K08556] |
|---|
| Pathway |
|
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| Metabolism |
Enzyme: CYP3A4 [HSA: 1576], CYP2C19 [HSA: 1557]
|
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| Interaction |
|
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| Structure map |
| Glucocorticoid and meneralocorticoid receptor agonists/antagonists | | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
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| Brite |
Therapeutic category of drugs in Japan [BR:br08301]
2 Agents affecting individual organs
24 Hormones
247 Estrogen and progesterone preparations
2477 Progesterones
D00066 Progesterone (JP16/USP/INN)
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03D PROGESTOGENS
G03DA Pregnen (4) derivatives
G03DA04 Progesterone
D00066 Progesterone (JP16/USP/INN)
USP drug classification [BR:br08302]
Hormonal Agents
Hormonal Agents, Stimulant / Replacement / Modifying (Sex Hormones/ Modifiers)
Progestins
Progesterone
D00066 Progesterone (JP16/USP/INN)
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
progesterone receptor [HSA:5241] [KO:K08556]
Progesterone [ATC:G03DA04]
D00066 Progesterone (JP16/USP/INN)
 |
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| Other DBs |
CAS: 57-83-0 PubChem: DrugBank: PDB-CCD: LigandBox: NIKKAJI: |
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| KCF data |
ATOM 23
1 C1y C 23.0350 -18.9936
2 C1y C 24.2088 -19.6769
3 C1z C 21.8554 -19.6827
4 C1x C 23.0233 -17.6271
5 C1y C 25.4002 -18.9819
6 C1x C 24.1913 -21.0784
7 C2y C 21.8554 -21.0375
8 C1x C 20.6873 -19.0112
9 C1a C 21.8437 -18.2754
10 C1x C 24.2030 -16.9322
11 C1z C 25.4060 -17.6097
12 C1x C 27.7653 -18.9936
13 C1x C 23.0409 -21.7092
14 C2x C 20.6873 -21.7150
15 C1x C 19.5194 -19.6827
16 C1y C 26.5974 -16.9263
17 C1a C 25.3943 -16.2081
18 C1x C 27.7712 -17.6213
19 C5x C 19.5194 -21.0375
20 C5a C 26.6032 -15.5948
21 O5x O 18.3690 -21.6975
22 C1a C 25.3885 -14.8823
23 O5a O 27.8121 -14.8882
BOND 26
1 1 2 1
2 1 3 1
3 1 4 1
4 2 5 1
5 2 6 1
6 3 7 1
7 3 8 1
8 3 9 1 #Up
9 4 10 1
10 5 11 1
11 5 12 1
12 6 13 1
13 7 14 2
14 8 15 1
15 11 16 1
16 11 17 1 #Up
17 12 18 1
18 14 19 1
19 16 20 1 #Up
20 19 21 2
21 20 22 1
22 20 23 2
23 7 13 1
24 10 11 1
25 15 19 1
26 16 18 1
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