KEGG   DRUG: DinoprostoneHelp
Entry
D00079                      Drug                                   

Name
Dinoprostone (JAN/USP/INN);
Cervidil (TN);
Prepidil (TN);
Prostin E2 (TN)
Product
Formula
C20H32O5
Exact mass
352.225
Mol weight
352.4651
Structure
Mol fileKCF fileDB searchJmolKegDraw
Simcomp SIMCOMP
Class
Other
 DG01961  Prostaglandin derivative
  DG01959  Prostaglandin E2 derivative
Unclassified
 DG02573  Prostanoid derivative
  DG01961  Prostaglandin derivative
   DG01959  Prostaglandin E2 derivative
Remark
Same as: 
Therapeutic category: 
ATC code: 
Chemical group: 
Efficacy
Oxytocic, Prostaglandin E2 receptor agonist
Comment
Prostaglandin derivative
Target
PTGER2 [HSA:5732] [KO:K04259]
  Pathway
Neuroactive ligand-receptor interaction
Interaction
Drug interaction
Structure map
Prostaglandins
Eicosanoid receptor agonists/antagonists
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 G GENITO URINARY SYSTEM AND SEX HORMONES
  G02 OTHER GYNECOLOGICALS
   G02A UTEROTONICS
    G02AD Prostaglandins
     G02AD02 Dinoprostone
      D00079  Dinoprostone (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  24  Hormones
   249  Miscellaneous
    2499  Others
     D00079  Dinoprostone (JAN/USP/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Prostaglandin
    Prostaglandin E2 receptor EP2 subtype
     Dinoprostone
      D00079  Dinoprostone (JAN/USP/INN)
Endocrine and hormonal agents [br08373.html]
 Other gynecological agents
  D00079
BRITE hierarchy
Other DBs
CAS: 
363-24-6
PubChem: 
ChEBI: 
ChEMBL: 
DrugBank: 
PDB-CCD: 
LigandBox: 
NIKKAJI: 
KCF data Show

ATOM        25
            1   C1y C    26.2804  -14.5224
            2   C1y C    26.2745  -15.8992
            3   C5x C    24.9670  -14.1058
            4   C1b C    27.6803  -12.8017
            5   C1y C    24.9902  -16.3216
            6   C2b C    27.4605  -16.9945
            7   C1x C    24.1745  -15.2223
            8   O5x O    24.5274  -12.7696
            9   C2b C    28.8604  -13.4959
            10  O1a O    24.5563  -17.6696
            11  C2b C    28.6406  -16.3177
            12  C2b C    30.2084  -13.4959
            13  C1c C    29.8150  -16.9945
            14  C1b C    31.3828  -12.8017
            15  C1b C    31.0010  -16.3177
            16  O1a O    29.8150  -18.3598
            17  C1b C    32.5513  -13.4786
            18  C1b C    32.1810  -16.9945
            19  C1b C    33.7315  -12.7961
            20  C1b C    33.3785  -16.3177
            21  C6a C    34.9058  -13.4670
            22  C1b C    34.5471  -16.9945
            23  O6a O    36.1149  -12.7555
            24  O6a O    34.9180  -14.8553
            25  C1a C    35.7388  -16.3177
BOND        25
            1     1   2 1
            2     1   3 1
            3     1   4 1 #Down
            4     2   5 1
            5     2   6 1 #Up
            6     3   7 1
            7     3   8 2
            8     4   9 1
            9     5  10 1 #Down
            10    6  11 2
            11    9  12 2
            12   11  13 1
            13   12  14 1
            14   13  15 1
            15   13  16 1 #Down
            16   14  17 1
            17   15  18 1
            18   17  19 1
            19   18  20 1
            20   19  21 1
            21   20  22 1
            22   21  23 1
            23   21  24 2
            24   22  25 1
            25    5   7 1

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