| Entry |
|
|---|
| Name |
Protriptyline hydrochloride (USP);
Vivactil (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C19H21N. HCl
|
|---|
| Exact mass |
299.1441
|
|---|
| Mol weight |
299.8377
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG01728 Tricyclic antidepressant
|
|---|
| Remark |
| Product (DG00936): | D00484<US> |
|
|---|
| Efficacy |
Antidepressant |
|---|
| Disease |
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Interaction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N06 PSYCHOANALEPTICS
N06A ANTIDEPRESSANTS
N06AA Non-selective monoamine reuptake inhibitors
N06AA11 Protriptyline
D00484 Protriptyline hydrochloride (USP) <US>
USP drug classification [BR:br08302]
Antidepressants
Tricyclics
Protriptyline
D00484 Protriptyline hydrochloride (USP)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00936 Protriptyline
D00484 Protriptyline hydrochloride
DG01728 Tricyclic antidepressant
DG00936 Protriptyline
D00484 Protriptyline hydrochloride
Drug classes [BR:br08332]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
D00484 Protriptyline hydrochloride
Target-based classification of drugs [BR:br08310]
Transporters
Solute carrier family
SLC6
SLC6A2 (NAT1)
D00484 Protriptyline hydrochloride (USP) <US>
SLC6A4 (HTT)
D00484 Protriptyline hydrochloride (USP) <US>
Pharmacogenomic biomarkers [br08341.html]
Polymorphisms and mutations affecting drug response
D00484
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01730 Non-selective monoamine reuptake inhibitor
DG00936 Protriptyline
DG01728 Tricyclic antidepressant
DG00936 Protriptyline
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 21
1 C2x C 29.7357 -19.7447
2 C8y C 28.8940 -18.6356
3 C8y C 29.2291 -17.2794
4 C1y C 30.4895 -16.7016
5 C2x C 31.1409 -19.7699
6 C8y C 31.7425 -17.3236
7 C8y C 32.0289 -18.6917
8 C8x C 28.2225 -16.3115
9 C8x C 26.8811 -16.6994
10 C8x C 26.5460 -18.0556
11 C8x C 27.5527 -19.0232
12 C8x C 33.3594 -19.1286
13 C8x C 34.4032 -18.1946
14 C8x C 34.1169 -16.8265
15 C8x C 32.7861 -16.3897
16 C1b C 30.4895 -15.3023
17 C1b C 31.7069 -14.5992
18 C1b C 32.9269 -15.3032
19 N1b N 34.1529 -14.5944
20 C1a C 35.3774 -15.3002
21 X Cl 37.5787 -18.3359
BOND 22
1 3 4 1
2 1 5 2
3 4 6 1
4 2 3 1
5 5 7 1
6 1 2 1
7 6 7 1
8 3 8 2
9 8 9 1
10 9 10 2
11 10 11 1
12 2 11 2
13 7 12 2
14 12 13 1
15 13 14 2
16 14 15 1
17 6 15 2
18 4 16 1
19 16 17 1
20 17 18 1
21 18 19 1
22 19 20 1
|
|---|
