KEGG   DRUG: D00537Help
Entry
D00537                      Drug                                   
Name Topiramate (JAN/USAN/INN);
Topamax (TN)
Formula C12H21NO8S
Mass 339.0988
Structure
Mol fileKCF fileDB searchJmolKegDraw
Target AMPA receptor antagonist [BR:hsa04000];
kainate receptor antagonist [BR:hsa04000];
voltage-gated sodium channel  blocker [HSA:6323];
voltage-gated sodium channel (SCN2A) blocker [HSA:6326];
voltage-gated sodium channel (SCN3A) blocker [HSA:6328];
voltage-gated sodium channel (SCN4A) blocker [HSA:6329];
voltage-gated sodium channel (SCN5A) blocker [HSA:6331];
voltage-gated sodium channel (SCN8A) blocker [HSA:6334];
voltage-gated sodium channel (SCN9A) blocker [HSA:6335]
Metabolism CYP3A4 [HSA:1576]
Activity Anticonvulsant
Remark Same as: C07502
Therapeutic category: 1139
ATC code: N03AX11
BRITE hierarchy
Pathway PATH: map07033  Anticonvulsants
Products
TOPIRAMATE (InvaGen Pharma), TOPIRAMATE (Teva Pharma), TOPIRAMATE (Teva Pharma), TOPIRAMATE (Zydus Pharma), TOPIRAMATE TABLETS (Ranbaxy Pharma), Topamax (Ortho-McNeil Neurologics)
Other DBs CAS: 97240-79-4
PubChem: 7847603
DrugBank: DB00273
PDB-CCD: TOR
LigandBox: D00537
NIKKAJI: J345.989F
KCF data Show

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