KEGG   DRUG: D00670Help
Entry
D00670                      Drug                                   
Name Donepezil hydrochloride (JAN/USAN);
Aricept (TN)
Formula C24H29NO3. HCl
Mass 415.1914
Structure
Mol fileKCF fileDB searchJmolKegDraw
Target acetylcholinesterase (AChE) inhibitor [HSA:43] [EC:3.1.1.7]
[PATH:hsa00564]
Metabolism CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
Activity Alzheimer's disease treatment [adjunct];
Dementia symptoms treatment adjunct;
Cognition adjuvant;
Inhibitor [acetylcholinesterase]
Remark Therapeutic category: 1190
ATC code: N06DA02
BRITE hierarchy
Pathway PATH: map07116  Butyrophenone family
PATH: map07220  Cholinergic and anticholinergic drugs
Products
ARICEPT (Eisai), ARICEPT (Eisai), Donepezil Hydrochloride (Teva Pharma)
Other DBs CAS: 120011-70-3
PubChem: 7847736
DrugBank: DB00843
LigandBox: D00670
NIKKAJI: J567.261I
KCF data Show

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