| Entry |
|
|---|
| Name |
Nalbuphine hydrochloride (USAN);
Nubain (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C21H27NO4. HCl
|
|---|
| Exact mass |
393.1707
|
|---|
| Mol weight |
393.9043
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Neuropsychiatric agent
DG01564 Opioid receptor agonist
Analgesic
DG01984 Opioid analgesics
|
|---|
| Remark |
| Product (DG00822): | D00843<US> |
|
|---|
| Efficacy |
Analgesic, Narcotic antagonist, Opioid receptor agonist/antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07224 | Opioid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N02 ANALGESICS
N02A OPIOIDS
N02AF Morphinan derivatives
N02AF02 Nalbuphine
D00843 Nalbuphine hydrochloride (USAN) <US>
USP drug classification [BR:br08302]
Analgesics
Opioid Analgesics, Short-acting
Nalbuphine
D00843 Nalbuphine hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00822 Nalbuphine
D00843 Nalbuphine hydrochloride
Analgesic
DG01984 Opioid analgesics
DG00822 Nalbuphine
D00843 Nalbuphine hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Opioid
OPRM1
D00843 Nalbuphine hydrochloride (USAN) <US>
OPRK1
D00843 Nalbuphine hydrochloride (USAN) <US>
OPRD1
D00843 Nalbuphine hydrochloride (USAN) <US>
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01564 Opioid receptor agonist
DG00822 Nalbuphine
Analgesic
DG01984 Opioid analgesics
DG00822 Nalbuphine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 27
1 X Cl 14.6606 -12.8905
2 C1z C 6.9594 -14.2694
3 C8y C 6.9594 -12.9454
4 C1z C 8.1440 -14.9661
5 C1y C 5.8445 -14.8965
6 C1x C 8.1440 -13.6423
7 C8y C 5.8445 -12.3183
8 C8y C 8.1440 -12.3183
9 C1y C 9.2589 -14.2694
10 C1x C 8.1440 -16.2204
11 O2x O 4.5206 -13.5725
12 C1y C 5.8445 -16.2204
13 C1x C 10.3737 -13.6423
14 C8y C 5.8445 -10.9944
15 C1x C 9.2589 -13.0151
16 C8x C 8.1440 -10.9944
17 N1y N 10.3737 -14.9661
18 C1x C 6.9594 -16.9172
19 O1a O 4.7297 -16.9172
20 C8x C 7.0291 -10.3673
21 O1a O 4.7297 -10.3673
22 O1a O 9.3982 -15.8720
23 C1b C 11.7726 -14.9661
24 C1y C 12.4755 -16.1834
25 C1x C 12.1154 -17.5269
26 C1x C 13.4590 -17.8870
27 C1x C 13.8190 -16.5434
BOND 31
1 2 3 1
2 2 4 1
3 2 5 1
4 2 6 1 #Up
5 3 7 2
6 3 8 1
7 4 9 1
8 4 10 1
9 5 11 1 #Down
10 5 12 1
11 6 13 1
12 7 14 1
13 8 15 1
14 8 16 2
15 9 17 1 #Up
16 10 18 1
17 12 19 1 #Down
18 14 20 2
19 14 21 1
20 7 11 1
21 9 15 1
22 12 18 1
23 13 17 1
24 16 20 1
25 4 22 1 #Up
26 17 23 1
27 23 24 1
28 24 25 1
29 25 26 1
30 26 27 1
31 24 27 1
|
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