| Entry |
|
|---|
| Name |
Paramethasone acetate (JAN/USAN);
Haldrone (TN) |
|---|
| Formula |
C24H31FO6
|
|---|
| Exact mass |
434.2105
|
|---|
| Mol weight |
434.4977
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
|
|---|
| Remark |
|
|---|
| Efficacy |
Anti-inflammatory, Immunosuppressant, Glucocorticoid receptor agonist |
|---|
| Comment |
fluorinated steroid
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07225 | Glucocorticoid and mineralocorticoid receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
H SYSTEMIC HORMONAL PREPARATIONS, EXCL. SEX HORMONES AND INSULINS
H02 CORTICOSTEROIDS FOR SYSTEMIC USE
H02A CORTICOSTEROIDS FOR SYSTEMIC USE, PLAIN
H02AB Glucocorticoids
H02AB05 Paramethasone
D01229 Paramethasone acetate (JAN/USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00508 Paramethasone
D01229 Paramethasone acetate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
3-Ketosteroid receptor
NR3C1 (GR)
D01229 Paramethasone acetate (JAN/USAN)
Drug groups [BR:br08330]
Anti-inflammatory
DG01955 Corticosteroid
DG02068 Glucocorticoid
DG00508 Paramethasone
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 31
1 C1y C 24.4746 -21.4862
2 C1y C 25.7237 -20.8091
3 C1y C 23.2954 -20.7915
4 C1x C 24.4746 -22.8522
5 C1z C 25.6713 -19.4489
6 C1x C 28.0120 -20.7682
7 C1z C 22.1104 -21.4745
8 C1y C 23.3071 -19.4314
9 C1y C 23.2837 -23.5293
10 C1z C 26.8563 -18.7834
11 C1x C 24.4980 -18.7543
12 C1a C 25.7646 -18.0888
13 C1y C 28.0296 -19.4782
14 C2y C 22.1046 -22.8405
15 C2x C 20.9254 -20.7857
16 C1a C 22.0346 -20.1611
17 O1a O 22.1280 -18.7367
18 X F 23.2780 -24.9069
19 C5a C 26.8737 -16.9917
20 O1a O 27.9829 -17.9488
21 C1a C 29.5005 -19.1279
22 C2x C 20.9254 -23.5234
23 C2x C 19.7347 -21.4745
24 C1b C 28.0704 -16.3262
25 O5a O 25.6947 -16.2970
26 C5x C 19.7347 -22.8405
27 O7a O 29.2437 -17.0208
28 O5x O 18.5554 -23.5234
29 C7a C 30.4609 -16.3357
30 C1a C 31.6626 -17.0471
31 O6a O 30.4761 -14.9391
BOND 34
1 1 4 1
2 2 5 1
3 2 6 1
4 3 7 1
5 3 8 1
6 4 9 1
7 5 10 1
8 5 11 1
9 5 12 1 #Up
10 6 13 1
11 7 14 1
12 7 15 1
13 7 16 1 #Up
14 8 17 1 #Up
15 9 18 1 #Down
16 10 19 1 #Up
17 10 20 1 #Down
18 13 21 1 #Down
19 14 22 2
20 15 23 2
21 19 24 1
22 19 25 2
23 22 26 1
24 24 27 1
25 26 28 2
26 8 11 1
27 9 14 1
28 10 13 1
29 23 26 1
30 27 29 1
31 1 2 1
32 29 30 1
33 1 3 1
34 29 31 2
|
|---|
