| Entry |
|
|---|
| Name |
Methixene hydrochloride (USAN);
Metixene hydrochloride (JAN);
Methixene hydrochloride hydrete;
Trest (TN) |
|---|
| Formula |
C20H23NS. HCl. H2O
|
|---|
| Exact mass |
363.1424
|
|---|
| Mol weight |
363.9445
|
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| Structure |
|
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| Simcomp |
|
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| Class |
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
|
|---|
| Remark |
|
|---|
| Efficacy |
Antiparkinsonian, Smooth muscle relaxant, Muscarinic acetylcholine receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
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| Interaction |
|
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| Structure map |
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N04 ANTI-PARKINSON DRUGS
N04A ANTICHOLINERGIC AGENTS
N04AA Tertiary amines
N04AA03 Metixene
D01871 Methixene hydrochloride (USAN)
Risk category of Japanese OTC drugs [BR:br08312]
Second-class OTC drugs
Inorganic and organic chemicals
Metixene
D01871 Methixene hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00853 Metixene
D01871 Methixene hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Acetylcholine (muscarinic)
CHRM
D01871 Methixene hydrochloride (USAN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01491 Muscarinic cholinergic receptor antagonist
DG01745 Anticholinergic antiparkinson agent
DG00853 Metixene
|
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| Other DBs |
|
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| KCF data |
ATOM 24
1 C8x C 20.6003 -20.4034
2 C8x C 20.6003 -21.8048
3 C8x C 21.8168 -22.5054
4 C8x C 21.8168 -19.7026
5 C8y C 23.0265 -20.4034
6 C8y C 23.0205 -21.8048
7 S2x S 24.2312 -22.5107
8 C1y C 24.2430 -19.7079
9 C8y C 25.4537 -20.4137
10 C8y C 25.5111 -21.8116
11 C8x C 26.6451 -22.5212
12 C8x C 27.8620 -21.8335
13 C8x C 27.8746 -20.4356
14 C8x C 26.6704 -19.7259
15 C1b C 24.2490 -18.3064
16 C1y C 25.4657 -17.6110
17 C1x C 26.6716 -18.3176
18 N1y N 27.8882 -17.6222
19 C1x C 27.8941 -16.2208
20 C1x C 26.6835 -15.5148
21 C1x C 25.4669 -16.2104
22 C1a C 29.0988 -18.3279
23 X Cl 30.3104 -20.0648
24 O0 O 30.8519 -21.7215
BOND 25
1 4 1 1
2 9 10 2
3 10 11 1
4 11 12 2
5 12 13 1
6 13 14 2
7 14 9 1
8 8 15 1
9 1 2 2
10 15 16 1
11 5 6 1
12 6 7 1
13 7 10 1
14 9 8 1
15 8 5 1
16 16 17 1
17 17 18 1
18 18 19 1
19 19 20 1
20 20 21 1
21 21 16 1
22 2 3 1
23 18 22 1
24 3 6 2
25 5 4 2
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