KEGG   DRUG: Moxalactam disodium
Entry
D02198                      Drug                                   
Name
Moxalactam disodium (USAN);
Latamoxef sodium (JP18);
Moxam (TN);
Shiomarin (TN)
Formula
C20H18N6O9S. 2Na
Exact mass
564.0651
Mol weight
564.4363
Structure
Simcomp
Class
Antibacterial
 DG01710  beta-Lactam antibiotic
  DG01714  Cephalosporin skeleton group
   DG01459  Oxacephem
 DG01776  Third-generation cephalosporin
Remark
Therapeutic category: 6133
ATC code: J01DD06
Chemical structure group: DG00575
Product (DG00575): D02198<JP>
Efficacy
Antibacterial, Cell wall biosynthesis inhibitor
Target
penicillin binding protein
  Pathway
ko00550  Peptidoglycan biosynthesis
Interaction
Brite
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
 J ANTIINFECTIVES FOR SYSTEMIC USE
  J01 ANTIBACTERIALS FOR SYSTEMIC USE
   J01D OTHER BETA-LACTAM ANTIBACTERIALS
    J01DD Third-generation cephalosporins
     J01DD06 Latamoxef
      D02198  Moxalactam disodium (USAN) <JP>
Therapeutic category of drugs in Japan [BR:br08301]
 6  Agents against pathologic organisms and parasites
  61  Antibiotics
   613  Acting mainly on gram-positive and gram-negative bacteria
    6133  Oxacephem antibioitics
     D02198  Moxalactam disodium (USAN); Latamoxef sodium (JP18)
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01459  Oxacephem
     DG00575  Latamoxef
      D02198  Moxalactam disodium
  DG01776  Third-generation cephalosporin
   DG00575  Latamoxef
    D02198  Moxalactam disodium
Drug classes [BR:br08332]
 Antibacterial
  DG01459  Oxacephem
   D02198  Moxalactam disodium
Antimicrobials [BR:br08307]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    D02198  Moxalactam disodium (USAN) <JP>
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D02198  Latamoxef sodium
Drug groups [BR:br08330]
 Antibacterial
  DG01710  beta-Lactam antibiotic
   DG01714  Cephalosporin skeleton group
    DG01459  Oxacephem
     DG00575  Latamoxef
  DG01776  Third-generation cephalosporin
   DG00575  Latamoxef
Antimicrobials abbreviations [BR:br08327]
 Antibacterials
  Cell wall biosynthesis inhibitor, beta-lactam
   Third-generation cephalosporin
    DG00575  Latamoxef
Other DBs
CAS: 64953-12-4
PubChem: 7849258
LigandBox: D02198
NIKKAJI: J24.501A
KCF data

ATOM        38
            1   C1z C    25.6917  -18.5859
            2   C5x C    25.6917  -19.9823
            3   N1y N    27.0881  -19.9823
            4   C1y C    27.0881  -18.5859
            5   N1b N    24.5048  -17.8878
            6   C5a C    23.3179  -18.5859
            7   O5x O    24.5048  -20.6805
            8   O5a O    23.3179  -19.9823
            9   C1c C    22.0612  -17.8878
            10  C6a C    22.0612  -16.4913
            11  O6a O    23.3179  -15.7932
            12  O6a O    20.8743  -15.7932 #-
            13  C2y C    28.3005  -20.6823
            14  C2y C    29.5130  -19.9823
            15  C1x C    29.5130  -18.5859
            16  O2x O    28.3005  -17.8859
            17  C6a C    28.3001  -22.0499
            18  O6a O    27.0724  -22.7583
            19  O6a O    29.4972  -22.7416 #-
            20  C1b C    30.7310  -20.6858
            21  S2a S    31.9279  -19.9955
            22  C8y C    33.1446  -20.6985
            23  N5x N    33.6202  -22.0237
            24  N5x N    35.0382  -22.0475
            25  N5x N    35.4305  -20.6160
            26  N4y N    34.2573  -19.8208
            27  O2a O    25.6917  -16.8359
            28  C1a C    26.8880  -16.1456
            29  C1a C    34.2091  -18.4554
            30  C8y C    20.8321  -18.6105
            31  C8x C    19.6394  -17.9344
            32  C8x C    18.4325  -18.6439
            33  C8y C    18.4436  -20.0439
            34  C8x C    19.6363  -20.7200
            35  C8x C    20.8432  -20.0105
            36  O1a O    17.2229  -20.7621
            37  Z   Na   31.0100  -22.8200 #+
            38  Z   Na   18.8300  -15.7500 #+
BOND        39
            1     1   2 1
            2     2   3 1
            3     3   4 1
            4     1   4 1
            5     1   5 1 #Up
            6     5   6 1
            7     2   7 2
            8     6   8 2
            9     6   9 1
            10    9  10 1
            11   10  11 2
            12   10  12 1
            13    3  13 1
            14   13  14 2
            15   14  15 1
            16   15  16 1
            17    4  16 1
            18   13  17 1
            19   17  18 2
            20   17  19 1
            21   14  20 1
            22   20  21 1
            23   21  22 1
            24   22  23 2
            25   23  24 1
            26   24  25 2
            27   25  26 1
            28   22  26 1
            29    1  27 1 #Down
            30   27  28 1
            31   26  29 1
            32    9  30 1
            33   30  31 2
            34   31  32 1
            35   32  33 2
            36   33  34 1
            37   34  35 2
            38   30  35 1
            39   33  36 1

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