| Entry |
|
|---|
| Name |
Dapiprazole hydrochloride (USAN);
Rev-Eyes (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C19H27N5. HCl
|
|---|
| Exact mass |
361.2033
|
|---|
| Mol weight |
361.9121
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
|
|---|
| Remark |
| Product (DG01140): | D03648<US> |
|
|---|
| Efficacy |
Antiglaucoma, Neuroleptic, alpha-Adrenergic receptor antagonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
| hsa04270 | Vascular smooth muscle contraction |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
S SENSORY ORGANS
S01 OPHTHALMOLOGICALS
S01E ANTIGLAUCOMA PREPARATIONS AND MIOTICS
S01EX Other antiglaucoma preparations
S01EX02 Dapiprazole
D03648 Dapiprazole hydrochloride (USAN) <US>
Drug groups [BR:br08330]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01140 Dapiprazole
D03648 Dapiprazole hydrochloride
Drug classes [BR:br08332]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
D03648 Dapiprazole hydrochloride
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA1
D03648 Dapiprazole hydrochloride (USAN) <US>
Drug groups [BR:br08330]
Ophthalmic agent
DG03201 Intraocular pressure lowering agent
DG01140 Dapiprazole
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 25
1 X Cl 35.3769 -18.0919
2 C1x C 20.5800 -17.1500
3 C1x C 20.5800 -18.4800
4 C1x C 21.7700 -19.1800
5 C8y C 23.0300 -18.4800
6 N4y N 23.0300 -17.1500
7 C1x C 21.7700 -16.4500
8 N5x N 24.3600 -18.9700
9 N5x N 25.1300 -17.7800
10 C8y C 24.3600 -16.6600
11 C1b C 24.7800 -15.3300
12 C1b C 26.1100 -15.0500
13 N1y N 27.0900 -16.1700
14 C1x C 26.6700 -17.5000
15 C1x C 27.5800 -18.4800
16 N1y N 28.9800 -18.2000
17 C1x C 29.4000 -16.8700
18 C1x C 28.4900 -15.8200
19 C8y C 29.8900 -19.2500
20 C8x C 29.1900 -20.5100
21 C8x C 29.8200 -21.7000
22 C8x C 31.2200 -21.7000
23 C8x C 31.9900 -20.5100
24 C8y C 31.2900 -19.3200
25 C1a C 32.0600 -18.0600
BOND 27
1 2 3 1
2 3 4 1
3 4 5 1
4 5 6 1
5 6 7 1
6 2 7 1
7 5 8 2
8 8 9 1
9 9 10 2
10 6 10 1
11 10 11 1
12 11 12 1
13 12 13 1
14 13 14 1
15 14 15 1
16 15 16 1
17 16 17 1
18 17 18 1
19 13 18 1
20 16 19 1
21 19 20 2
22 20 21 1
23 21 22 2
24 22 23 1
25 23 24 2
26 19 24 1
27 24 25 1
|
|---|
