| Entry |
|
|---|
| Name |
Estradiol cypionate (USP);
Depo-estradiol (TN) |
|---|
| Product |
|
|---|
| Generic |
|
|---|
| Formula |
C26H36O3
|
|---|
| Exact mass |
396.2664
|
|---|
| Mol weight |
396.5622
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Hormonal agent
DG01986 Estrogen
DG01584 Estrogen receptor agonist
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
|
|---|
| Remark |
| Product (DG00462): | D00105<JP/US> D01413<JP/US> D04061<US> D04063<US> D07918<US> |
|
|---|
| Efficacy |
Menstruation disorder agent, Estrogen receptor agonist |
|---|
| Comment |
Estrogen
|
|---|
| Target |
|
|---|
| Pathway |
|
|---|
| Metabolism |
Enzyme: CYP3A4 [HSA: 1576]
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07226 | Progesterone, androgen and estrogen receptor agonists/antagonists |
|
|---|
| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
G GENITO URINARY SYSTEM AND SEX HORMONES
G03 SEX HORMONES AND MODULATORS OF THE GENITAL SYSTEM
G03C ESTROGENS
G03CA Natural and semisynthetic estrogens, plain
G03CA03 Estradiol
D04063 Estradiol cypionate (USP) <US>
USP drug classification [BR:br08302]
Hormonal Agents, Stimulant/Replacement/Modifying (Sex Hormones/Modifiers)
Estrogens
Estradiol
D04063 Estradiol cypionate (USP)
Drug groups [BR:br08330]
Hormonal agent
DG01986 Estrogen
DG00462 Estradiol
D04063 Estradiol cypionate
DG01584 Estrogen receptor agonist
DG00462 Estradiol
D04063 Estradiol cypionate
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00462 Estradiol
D04063 Estradiol cypionate
Drug classes [BR:br08332]
Endocrine and hormonal agent
DG01986 Estrogen
D04063 Estradiol cypionate
DG01584 Estrogen receptor agonist
D04063 Estradiol cypionate
Target-based classification of drugs [BR:br08310]
Nuclear receptors
Estrogen like receptors
Estrogen receptor
NR3A (ESR)
D04063 Estradiol cypionate (USP) <US>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D04063
Drug groups [BR:br08330]
Hormonal agent
DG01986 Estrogen
DG00462 Estradiol
DG01584 Estrogen receptor agonist
DG00462 Estradiol
Metabolizing enzyme substrate
DG01633 CYP3A/CYP3A4 substrate
DG02913 CYP3A4 substrate
DG00462 Estradiol
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 29
1 C8x C 15.3591 -19.1390
2 C8y C 15.3591 -20.4708
3 C8x C 16.5507 -21.1718
4 C8y C 17.7425 -20.4708
5 C8y C 17.7425 -19.1390
6 C8x C 16.5507 -18.4380
7 C1x C 18.9340 -21.1718
8 C1x C 20.1257 -20.4708
9 C1y C 20.1257 -19.1390
10 C1y C 18.9340 -18.4380
11 C1y C 21.3173 -18.4380
12 C1z C 21.3173 -17.1062
13 C1x C 20.1257 -16.4053
14 C1x C 18.9340 -17.1062
15 C1x C 23.6305 -18.4380
16 C1x C 23.6305 -17.1062
17 C1y C 22.4388 -16.4053
18 O7a O 22.4388 -15.0734
19 C1a C 21.3173 -15.7043
20 O1a O 14.1675 -21.1718
21 C7a C 23.6305 -14.3725
22 C1b C 24.8221 -15.0734
23 O6a O 23.6305 -12.9705
24 C1b C 26.0138 -14.3725
25 C1y C 27.2054 -15.0734
26 C1x C 27.6260 -16.4053
27 C1x C 29.0279 -16.4053
28 C1x C 29.4486 -15.0734
29 C1x C 28.3269 -14.2323
BOND 33
1 1 2 1
2 2 3 2
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 2
7 4 7 1
8 7 8 1
9 8 9 1
10 9 10 1
11 5 10 1
12 9 11 1
13 11 12 1
14 12 13 1
15 13 14 1
16 10 14 1
17 11 15 1
18 15 16 1
19 16 17 1
20 12 17 1
21 17 18 1 #Up
22 12 19 1 #Up
23 2 20 1
24 18 21 1
25 21 22 1
26 21 23 2
27 22 24 1
28 24 25 1
29 25 26 1
30 26 27 1
31 27 28 1
32 28 29 1
33 25 29 1
|
|---|
