| Entry |
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| Name |
Prasugrel hydrochloride (JAN/USAN);
Effient (TN)
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| Product |
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| Formula |
C20H20FNO3S. HCl
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| Exact mass |
409.0915
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| Mol weight |
409.902
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| Structure |
     |
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| Activity |
Inhibits platelet aggregation [platelet ADPP 2Y12 antagonist]
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| Remark |
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| Target |
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| Interaction |
Genomic biomarker: CYP2C19 [HSA: 1557]
CYP inhibition: CYP2B6 [HSA: 1555]
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
B BLOOD AND BLOOD FORMING ORGANS
B01 ANTITHROMBOTIC AGENTS
B01A ANTITHROMBOTIC AGENTS
B01AC Platelet aggregation inhibitors excl. heparin
B01AC22 Prasugrel
D05597 Prasugrel hydrochloride (JAN/USAN)
USP drug classification [BR:br08302]
Blood Products / Modifiers / Volume Expanders
Platelet Modifying Agents
Adenosine Diphosphate P2Y12 Inhibitors
Prasugrel
D05597 Prasugrel hydrochloride (JAN/USAN)
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Purine / pyrimidine
P2Y12 receptor [HSA:64805] [KO:K04298]
Prasugrel [ATC:B01AC22]
D05597 Prasugrel hydrochloride (USAN)
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| Other DBs |
CAS: 389574-19-0 PubChem: LigandBox: |
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| KCF data |
ATOM 27
1 N1y N 15.4700 -16.3800
2 C1x C 15.4700 -14.9800
3 C1x C 16.6600 -14.2800
4 C8y C 17.9200 -14.9800
5 C8y C 17.9200 -16.3800
6 C1x C 16.6600 -17.0800
7 S2x S 19.2500 -14.5600
8 C8y C 20.0200 -15.6800
9 C8x C 19.2500 -16.8000
10 O7a O 21.4200 -15.6800
11 C7a C 22.1200 -14.4900
12 C1a C 23.5200 -14.4900
13 O6a O 21.4200 -13.3000
14 C1c C 14.2800 -17.0800
15 C8y C 13.0900 -16.3800
16 C5a C 14.2800 -18.4800
17 O5a O 13.0900 -19.1800
18 C1y C 15.4700 -19.1800
19 C8x C 13.0900 -14.9800
20 C8x C 11.8300 -14.2800
21 C8x C 10.6400 -14.9800
22 C8x C 10.6400 -16.3800
23 C8y C 11.8300 -17.0800
24 X F 11.8300 -18.4800
25 C1x C 16.8700 -19.1800
26 C1x C 16.1700 -20.3700
27 X Cl 23.2400 -18.6900
BOND 29
1 1 2 1
2 2 3 1
3 3 4 1
4 4 5 2
5 5 6 1
6 1 6 1
7 4 7 1
8 7 8 1
9 8 9 2
10 5 9 1
11 8 10 1
12 10 11 1
13 11 12 1
14 11 13 2
15 1 14 1
16 14 15 1
17 14 16 1
18 16 17 2
19 16 18 1
20 15 19 2
21 19 20 1
22 20 21 2
23 21 22 1
24 22 23 2
25 15 23 1
26 23 24 1
27 18 25 1
28 25 26 1
29 26 18 1
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