| Entry |
|
|---|
| Name |
Medetomidine (INN);
Domitor [veterinary] (TN) |
|---|
| Formula |
C13H16N2
|
|---|
| Exact mass |
200.1313
|
|---|
| Mol weight |
200.2795
|
|---|
| Structure |
|
|---|
| Simcomp |
|
|---|
| Class |
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
|
|---|
| Remark |
|
|---|
| Efficacy |
Analgesic (veterinary), Sedative-hypnotic (veterinary), alpha2-Adrenergic receptor agonist |
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Brite |
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG01320 Medetomidine
D08165 Medetomidine
Target-based classification of drugs [BR:br08310]
G Protein-coupled receptors
Rhodopsin family
Adrenaline
ADRA2
D08165 Medetomidine (INN)
Drug groups [BR:br08330]
Cardiovascular agent
DG01456 Adrenergic receptor agonist
DG01450 alpha-Adrenergic receptor agonist
DG01449 alpha2-Adrenergic receptor agonist
DG01320 Medetomidine
|
|---|
| Other DBs |
|
|---|
| KCF data |
ATOM 15
1 C8y C 21.2800 -17.9200
2 C8x C 21.2800 -19.3200
3 C8x C 22.4700 -20.0200
4 C8x C 23.7300 -19.3200
5 C8y C 23.7300 -17.9200
6 C8y C 22.4700 -17.2200
7 C8x C 26.1100 -19.3200
8 C8y C 26.1100 -17.9200
9 C1c C 24.9200 -17.2200
10 N4x N 27.4400 -19.7400
11 C8x C 28.2800 -18.6200
12 N5x N 27.4400 -17.5000
13 C1a C 24.9200 -15.8200
14 C1a C 22.4700 -15.8200
15 C1a C 20.0900 -17.2200
BOND 16
1 1 2 2
2 2 3 1
3 3 4 2
4 4 5 1
5 5 6 2
6 1 6 1
7 7 8 2
8 8 9 1
9 5 9 1
10 7 10 1
11 10 11 1
12 11 12 2
13 8 12 1
14 9 13 1
15 6 14 1
16 1 15 1
|
|---|
