| Entry |
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| Name |
Tangier disease
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| Description |
Tangier disease is an autosomal recessive disorder caused by mutation of ABCA1 gene leading to the accumulation of cholesterol in tissue macrophages and prevalent atherosclerosis.
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| Category |
Inherited metabolic disease; Nervous system disease
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| Pathway |
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| Gene |
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| Other DBs |
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| Reference |
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| Authors |
Nofer JR, Remaley AT |
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| Title |
Tangier disease: still more questions than answers. |
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| Journal |
Cell Mol Life Sci 62:2150-60 (2005) |
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| Reference |
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| Authors |
Oram JF |
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| Title |
Molecular basis of cholesterol homeostasis: lessons from Tangier disease and ABCA1. |
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| Journal |
Trends Mol Med 8:168-73 (2002) |
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| Reference |
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| Authors |
Oram JF |
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| Title |
Tangier disease and ABCA1. |
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| Journal |
Biochim Biophys Acta 1529:321-30 (2000) |
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