KEGG   DISEASE: H00277Help
Entry
H00277                      Disease                                

Name
Enterohemorrhagic Escherichia coli (EHEC) infection
Description
Enterohaemorrhagic Escherichia coli (EHEC) infection is typically contracted through consumption of contaminated food or contact with contaminated water, animal feces or infected animals. EHEC is also referred to as verocytotoxin producing E. coli (VTEC) or Shiga toxin producing E. coli (STEC). The serotype O157:H7 is first associated with human disease after a multistate outbreak in the United States in 1982 involving contaminated hamburgers. The symptoms of EHEC infection range from mild diarrhea to hemorrhagic colitis and can progress to a severe cases called hemolytic uremic syndrome (HUS).
Category
Infectious disease
BRITE hierarchy
Pathway
Pathogenic Escherichia coli infection
Pathogen
Escherichia coli O157:H7 [GN:ece ecs ecf etw elx]
Escherichia coli O26:H11 [GN:eoj]
Escherichia coli O111:H- [GN:eoi]
Escherichia coli O103:H2 [GN:eoh]
Escherichia coli O104:H4 [GN:eso esm esl]
Escherichia coli O145:H28 [GN:ecoo ecoh]
shiga toxin [KO:K11006 K11007]
pore-forming toxin [KO:K11003 K11004 K11005]
Other DBs
ICD-10: 
MeSH: 
Reference
  Authors
Baker DR, Moxley RA, Steele MB, Lejeune JT, Christopher-Hennings J, Chen DG, Hardwidge PR, Francis DH
  Title
Differences in virulence among Escherichia coli O157:H7 strains isolated from humans during disease outbreaks and from healthy cattle.
  Journal
Appl Environ Microbiol 73:7338-46 (2007)
Reference
  Authors
Ahmed SA, Awosika J, Baldwin C, Bishop-Lilly KA, Biswas B, Broomall S, Chain PS, Chertkov O, Chokoshvili O, Coyne S, Davenport K, Detter JC, Dorman W, Erkkila TH, Folster JP, Frey KG, George M, Gleasner C, Henry M, Hill KK, Hubbard K, Insalaco J, Johnson S, Kitzmiller A, Krepps M, Lo CC, Luu T, McNew LA, Minogue T, Munk CA, Osborne B, Patel M, Reitenga KG, Rosenzweig CN, Shea A, Shen X, Strockbine N, Tarr C, Teshima H, van Gieson E, Verratti K, Wolcott M, Xie G, Sozhamannan S, Gibbons HS
  Title
Genomic comparison of Escherichia coli O104:H4 isolates from 2009 and 2011 reveals plasmid, and prophage heterogeneity, including shiga toxin encoding phage stx2.
  Journal
PLoS One 7:e48228 (2012)

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