KEGG   DISEASE: H00309Help
Entry
H00309                      Disease                                

Name
Acinetobacter infection
Description
Acinetobacter baumannii has emerged as a worldwide problem as a nosocomial pathogen in hospitalized patients. It can cause bacteremia, pneumonia, meningitis, urinary tract infection, wound infection, and nosocomial infections with mortality rates of 20 to 60%. Isolates resistant to almost all commercially available antimicrobials have been identified.
Category
Infectious disease
BRITE hierarchy
Pathogen
Acinetobacter baumannii [GN:acb abm aby abc abn abb abx abz abr abd abh abad]
Drug
Colistin sulfate [DR:D02138]
Other DBs
ICD-10: 
MeSH: 
Reference
PMID:18444865 (drug)
  Authors
Maragakis LL, Perl TM
  Title
Acinetobacter baumannii: epidemiology, antimicrobial resistance, and treatment options.
  Journal
Clin Infect Dis 46:1254-63 (2008)
Reference
PMID:16008625 (drug)
  Authors
Petrosillo N, Chinello P, Proietti MF, Cecchini L, Masala M, Franchi C, Venditti M, Esposito S, Nicastri E
  Title
Combined colistin and rifampicin therapy for carbapenem-resistant Acinetobacter baumannii infections: clinical outcome and adverse events.
  Journal
Clin Microbiol Infect 11:682-3 (2005)
Reference
PMID:16048915 (drug)
  Authors
Kasiakou SK, Michalopoulos A, Soteriades ES, Samonis G, Sermaides GJ, Falagas ME
  Title
Combination therapy with intravenous colistin for management of infections due to multidrug-resistant Gram-negative bacteria in patients without cystic fibrosis.
  Journal
Antimicrob Agents Chemother 49:3136-46 (2005)
Reference
PMID:21502736 (desciption)
  Authors
Doughari HJ, Ndakidemi PA, Human IS, Benade S
  Title
The ecology, biology and pathogenesis of Acinetobacter spp.: an overview.
  Journal
Microbes Environ 26:101-12 (2011)
Reference
PMID:15280512 (description)
  Authors
Jain R, Danziger LH
  Title
Multidrug-resistant Acinetobacter infections: an emerging challenge to clinicians.
  Journal
Ann Pharmacother 38:1449-59 (2004)
Reference
PMID:18588496 (description)
  Authors
Gootz TD, Marra A
  Title
Acinetobacter baumannii: an emerging multidrug-resistant threat.
  Journal
Expert Rev Anti Infect Ther 6:309-25 (2008)
Reference
PMID:16238638 (drug)
  Authors
Hanlon GW
  Title
The emergence of multidrug resistant Acinetobacter species: a major concern in the hospital setting.
  Journal
Lett Appl Microbiol 41:375-8 (2005)

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