KEGG   DISEASE: H00333Help
Entry
H00333                      Disease                                

Name
Streptococcal infection
Description
Streptococci are gram-positive bacteria. The beta-hemolytic streptococci are divided into two groups: group A Streptococcus (GAS) that causes over 600 million cases of infections each year, ranging from mild pharyngitis to severe streptococcal toxic shock-like syndrome (STSS), and group B Streptococcus (GBS) that causes neonatal invasive infections including sepsis, pneumonia, and meningitis.
Category
Infectious disease
BRITE hierarchy
Pathogen
Streptococcus pyogenes [GN:spy spz spym spm spg sps sph spi spj spk spf spa spb soz] (Severe invasive streptococcal infection / Streptococcal toxic shock-like syndrome, Group A Streptococcus infection)
Streptococcus agalactiae [GN:sag sak san] (Group B Streptococcus infection)
pore-forming toxin [KO:K11031 K11045 K11046]
pore-forming toxin [KO:K11052]
superantigen [KO:K11040]
ADP-ribosyltransferase SpyA [KO:K11044]
Drug
Penicillin G potassium [DR:D01053]
Clindamycin [DR:D00277]
Erythromycin [DR:D00140]
Cephalosporins
Vancomycin [DR:D00212]
Azithromycin [DR:D06390]
Clarithromycin [DR:D00276]
Other DBs
Reference
(drug)
  Authors
McPhee SJ, Papadakis MA, Tierney LM (ed).
  Title
Current Medical Diagnosis & Treatment 2007, Forty-Sixth Edition
  Journal
The McGraw-Hill Companies, Inc. (2007)
Reference
PMID:21921933 (description)
  Authors
Cole JN, Barnett TC, Nizet V, Walker MJ
  Title
Molecular insight into invasive group A streptococcal disease.
  Journal
Nat Rev Microbiol 9:724-36 (2011)
Reference
PMID:21415743 (description)
  Authors
Lynskey NN, Lawrenson RA, Sriskandan S
  Title
New understandings in Streptococcus pyogenes.
  Journal
Curr Opin Infect Dis 24:196-202 (2011)
Reference
PMID:21672083 (description)
  Authors
Melin P
  Title
Neonatal group B streptococcal disease: from pathogenesis to preventive strategies.
  Journal
Clin Microbiol Infect 17:1294-303 (2011)

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