KEGG   DISEASE: H00343Help
Entry
H00343                      Disease                                

Name
Diphtheria
Description
Diphtheria is a contagious and potentially life-threatening childhood disease caused by Corynebacterium diphtheriae. In industrialized countries, immunization against diphtheria became widespread in the 1940s and the incidence of the disease markedly decreased. However, diphtheria still remains endemic in several regions including Africa, India, Bangladesh, Vietnam, the tropics, and South America. Moreover, a large proportion of adults in industrialized countries are now susceptible to diphtheria because the protection by vaccine does not last for long time unless periodic booster is given.
Category
Infectious disease
BRITE hierarchy
Pathogen
Corynebacterium diphtheriae [GN:cdi cdd cdw cdz]
diphtheria toxin [KO:K00776]
Drug
Benzylpenicillin potassium [DR:D01053]
Erythromycin [DR:D00140 D01361 D02009 D02184]
Other DBs
ICD-10: 
MedlinePlus: 
Reference
(drug)
  Authors
Papadakis MA, Tierney LM (ed).
  Title
[Current Medical Diagnosis & Treatment 2004, Forty-Third Edition] (In Japanese)
  Journal
Nikkei Business Publications, Inc. (2004)
Reference
PMID:15049077 (description)
  Authors
Mattos-Guaraldi AL, Moreira LO, Damasco PV, Hirata Junior R
  Title
Diphtheria remains a threat to health in the developing world--an overview.
  Journal
Mem Inst Oswaldo Cruz 98:987-93 (2003)
Reference
PMID:7489768 (description)
  Authors
Galazka AM, Robertson SE
  Title
Diphtheria: changing patterns in the developing world and the industrialized world.
  Journal
Eur J Epidemiol 11:107-17 (1995)
Reference
PMID:7489783 (description)
  Authors
Galazka AM, Robertson SE, Oblapenko GP
  Title
Resurgence of diphtheria.
  Journal
Eur J Epidemiol 11:95-105 (1995)

» Japanese version

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