KEGG   DISEASE: NocardiosisHelp
Entry
H00345                      Disease                                

Name
Nocardiosis
Description
Nocardiosis is an uncommon gram-positive bacterial infection that affects mainly patients with deficient cell-mediated immunity. It has been reported worldwide in all ages and ethnic groups. Pulmonary disease is the most common clinical presentation especially in immunocompromised patients, accounting for more than 40% of reported cases. Nocardiosis also occurs in disseminated form, affecting lungs, central nervous system, skin, and the soft tissues. Primary cutaneous nocardiosis typically affects immunocompetent individuals with traumatic inoculation at the infected site.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Bacterial infections
  Infections caused by actinobacteria
   H00345  Nocardiosis
Human diseases in ICD-10 classification [BR:br08403]
 1. Certain infectious and parasitic diseases (A00-B99)
  A30-A49  Other bacterial diseases
   A43  Nocardiosis
    H00345  Nocardiosis
BRITE hierarchy
Pathogen
Nocardia farcinica [GN:nfa]
Nocardia brasiliensis
Nocardia asteroides sensu stricto
Nocardia nova
Nocardia cyriacigeorgica [GN:ncy]
Marker
16S rRNA (PCR detection) [KO:K01977]
Drug
Trimethoprim-sulfamethoxazole (TMP-SMZ) [DR:D00285]
Fluoroquinolone
Ceftriaxone [DG:DG00573]
Moxifloxacine
Imipenem [DG:DG01212]
Amikacin [DG:DG00403]
Other DBs
ICD-10: 
MeSH: 
MedlinePlus: 
Reference
PMID:20306281 (description, env_factor, drug)
  Authors
Ambrosioni J, Lew D, Garbino J
  Title
Nocardiosis: updated clinical review and experience at a tertiary center.
  Journal
Infection 38:89-97 (2010)
Reference
PMID:20463251 (decription, env_factor, drug)
  Authors
Sullivan DC, Chapman SW
  Title
Bacteria that masquerade as fungi: actinomycosis/nocardia.
  Journal
Proc Am Thorac Soc 7:216-21 (2010)
Reference
PMID:16614249 (description)
  Authors
Brown-Elliott BA, Brown JM, Conville PS, Wallace RJ Jr
  Title
Clinical and laboratory features of the Nocardia spp. based on current molecular  taxonomy.
  Journal
Clin Microbiol Rev 19:259-82 (2006)
Reference
PMID:18427245 (description, env_factor)
  Authors
Martinez R, Reyes S, Menendez R
  Title
Pulmonary nocardiosis: risk factors, clinical features, diagnosis and prognosis.
  Journal
Curr Opin Pulm Med 14:219-27 (2008)
Reference
PMID:19387343 (description)
  Authors
Lalitha P
  Title
Nocardia keratitis.
  Journal
Curr Opin Ophthalmol 20:318-23 (2009)

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