KEGG   DISEASE: H00363Help
H00363                      Disease                                

Candidiasis is a fungal infection with Candida species, predominantly with Candida albicans. Invasive candidiasis is a major cause of morbidity and mortality in the intensive care unit (ICU) setting, causing bloodstream infections. Recently, various non-C. albicans species have emerged as infecting agents. In patients with impaired IL-17 immunity, recurrent or persistent infections are observed (chronic mucocutaneous candidiasis disease).
Infectious disease
Infectious diseases [BR:br08401]
  Infections caused by ascomycetes
   H00363  Candidiasis
Human diseases in ICD-10 classification [BR:br08403]
 1. Certain infectious and parasitic diseases (A00-B99)
  B35-B49  Mycoses
   B37  Candidiasis
    H00363  Candidiasis
BRITE hierarchy
IL17RA [HSA:23765] [KO:K05164]
IL17F [HSA:112744] [KO:K05494]
STAT1 [HSA:6772] [KO:K11220]
Candida albicans [GN:cal]
Candida dubliniensis [GN:cdu]
Candida tropicalis [GN:ctp]
Candida glabrata [GN:cgr]
Clotrimazole [DR:D00282]
Fluconazole [DG:DG00371]
Isoconazole [DG:DG00365]
Itraconazole [DR:D00350]
Ketoconazole [DR:D00351]
Miconazole [DG:DG00004]
Nystatin [DR:D00202]
Other DBs
Papadakis MA, Tierney LM (ed).
[Current Medical Diagnosis & Treatment 2004, Forty-Third Edition] (In Japanese)
Nikkei Business Publications, Inc. (2004)
PMID:21486733 (description)
Rodloff C, Koch D, Schaumann R
Epidemiology and antifungal resistance in invasive candidiasis.
Eur J Med Res 16:187-95 (2011)
PMID:18279532 (description)
Mean M, Marchetti O, Calandra T
Bench-to-bedside review: Candida infections in the intensive care unit.
Crit Care 12:204 (2008)
PMID:21350122 (gene)
Puel A, Cypowyj S, Bustamante J, Wright JF, Liu L, Lim HK, Migaud M, Israel L, Chrabieh M, Audry M, Gumbleton M, Toulon A, Bodemer C, El-Baghdadi J, Whitters M, Paradis T, Brooks J, Collins M, Wolfman NM, Al-Muhsen S, Galicchio M, Abel L, Picard C, Casanova JL
Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17  immunity.
Science 332:65-8 (2011)
PMID:21727188 (gene)
Liu L, Okada S, Kong XF, Kreins AY, Cypowyj S, Abhyankar A, Toubiana J, Itan Y, Audry M, Nitschke P, Masson C, Toth B, Flatot J, Migaud M, Chrabieh M, Kochetkov T, Bolze A, Borghesi A, Toulon A, Hiller J, Eyerich S, Eyerich K, Gulacsy V, Chernyshova L, Chernyshov V, Bondarenko A, Maria Cortes Grimaldo R, Blancas-Galicia L, Madrigal Beas IM, Roesler J, Magdorf K, Engelhard D, Thumerelle C, Burgel PR, Hoernes M, Drexel B, Seger R, Kusuma T, Jansson AF, Sawalle-Belohradsky J, Belohradsky B, Jouanguy E, Bustamante J, Bue M, Karin N, Wildbaum G, Bodemer C, Lortholary O, Fischer A, Blanche S, Al-Muhsen S, Reichenbach J, Kobayashi M, Rosales FE, Lozano CT, Kilic SS, Oleastro M, Etzioni A, Traidl-Hoffmann C, Renner ED, Abel L, Picard C, Marodi L, Boisson-Dupuis S, Puel A, Casanova JL
Gain-of-function human STAT1 mutations impair IL-17 immunity and underlie chronic mucocutaneous candidiasis.
J Exp Med 208:1635-48 (2011)

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