KEGG   DISEASE: Hepatitis CHelp
Entry
H00413                      Disease                                

Name
Hepatitis C;
Hepatitis C virus (HCV) infection
Description
Hepatitis C is a blood-borne viral disease caused by Hepatitis C virus (HCV) belonging to the Flaviviridae family. HCV is a major cause of persistent liver disease, with approximately 170 million individuals infected worldwide. Up to 80% of patients will have chronic infection, 30-40 percent of these patients develop into degenerative liver disease including fibrosis and cirrhosis over 20 years after infection. Some of these patients will develop hepatocellular carcinoma. Treatment of chronic hepatitis C virus infections has undergone a huge transformation in recent years. Although interferon-based therapies have been the mainstay of treatment for HCV infection, new interferon-free therapies (direct acting antivirals) have recently been approved.
Category
Infectious disease
Brite
Infectious diseases [BR:br08401]
 Viral infections
  Infections caused by +ssRNA viruses
   H00413  Hepatitis C
Human diseases in ICD-10 classification [BR:br08403]
 1. Certain infectious and parasitic diseases (A00-B99)
  B15-B19  Viral hepatitis
   B17  Other acute viral hepatitis
    H00413  Hepatitis C
BRITE hierarchy
Pathway
hsa05160  Hepatitis C
Pathogen
Hepatitis C virus (HCV) [GN:T40066]
Drug
Ribavirin [DR:D00423]
Simeprevir sodium [DR:D10469]
Daclatasvir dihydrochloride [DR:D10105]
Sofosbuvir [DR:D10366]
Ledipasvir - sofosbuvir mixt [DR:D10578]
Dasabuvir - ombitasvir - paritaprevir -ritonavir mixt [DR:D10582]
Ombitasvir - paritaprevir -ritonavir mixt [DR:D10745]
Elbasvir - grazoprevir mixt [DR:D10778]
Sofosbuvir - velpatasvir mixt [DR:D10827]
Sofosbuvir - velpatasvir - voxilaprevir mixt [DR:D10900]
Interferon alfa-2b [DR:D02745]
Peginterferon alfa-2b [DR:D02748]
Peginterferon alfa-2a [DR:D02747]
Glecaprevir - pibrentasvir mixt [DR:D11014]
Other DBs
ICD-10: B17.1
MeSH: D006526
MedlinePlus: 000284

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