| Entry |
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| Name |
Tetralogy of Fallot
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| Description |
The four classic features of tetralogy of Fallot are ventricular septal defect, pulmonary stenosis, right ventricular hypertrophy, and overrinding aorta. These cardiac abnormalities are resulted from altered neural crest migration during embryogenesis.
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| Category |
Developmental disorder; Cardiac diseases
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| Pathway |
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| Gene |
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| Env factor |
Organic solvents
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| Other DBs |
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| Reference |
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| Authors |
Di Felice V, Zummo G |
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| Title |
Tetralogy of fallot as a model to study cardiac progenitor cell migration and differentiation during heart development. |
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| Journal |
Trends Cardiovasc Med 19:130-5 (2009) |
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| Reference |
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| Authors |
Karkera JD, Lee JS, Roessler E, Banerjee-Basu S, Ouspenskaia MV, Mez J, Goldmuntz E, Bowers P, Towbin J, Belmont JW, Baxevanis AD, Schier AF, Muenke M |
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| Title |
Loss-of-function mutations in growth differentiation factor-1 (GDF1) are associated with congenital heart defects in humans. |
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| Journal |
Am J Hum Genet 81:987-94 (2007) |
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| Reference |
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| Authors |
Jenkins KJ, Correa A, Feinstein JA, Botto L, Britt AE, Daniels SR, Elixson M, Warnes CA, Webb CL |
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| Title |
Noninherited risk factors and congenital cardiovascular defects: current knowledge: a scientific statement from the American Heart Association Council on Cardiovascular Disease in the Young: endorsed by the American Academy of Pediatrics. |
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| Journal |
Circulation 115:2995-3014 (2007) |
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