| Entry |
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| Name |
Schistosomiasis
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| Description |
Schistosomiasis is a parasitic disease caused by the genus Schistosoma parasites. Schistosomiasis is the third most devastating tropical disease in the world and WHO estimates 600 million people at risk of infection with 200 million infected. Among nonimmune patients, host's immune response to schistosome eggs leads to acute schistosomiasis that is characterized by cercarial dermatitis and 'Katayama fever'. Life-threatening cardiac and neurological complications may occur. Schistosome eggs can also leads to chronic fibrotic response in host tissues, causing gastrointestinal and liver diseases.
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| Category |
Infectious disease
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| Pathogen |
Schistosoma mansoni [GN: smm]
Schistosoma haematobium
Schistosoma japonicum
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| Drug |
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| Other DBs |
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| Reference |
PMID: 19292768 (description, env_factor, drug) |
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| Authors |
Burke ML, Jones MK, Gobert GN, Li YS, Ellis MK, McManus DP |
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| Title |
Immunopathogenesis of human schistosomiasis. |
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| Journal |
Parasite Immunol 31:163-76 (2009) |
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| Reference |
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| Authors |
Wilson MS, Mentink-Kane MM, Pesce JT, Ramalingam TR, Thompson R, Wynn TA |
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| Title |
Immunopathology of schistosomiasis. |
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| Journal |
Immunol Cell Biol 85:148-54 (2007) |
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| Reference |
PMID: 20222897 (description, env_factor, drug) |
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| Authors |
Jaureguiberry S, Paris L, Caumes E |
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| Title |
Acute schistosomiasis, a diagnostic and therapeutic challenge. |
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| Journal |
Clin Microbiol Infect 16:225-31 (2010) |
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