KEGG   DISEASE: HypomagnesemiaHelp
Entry
H01210                      Disease                                

Name
Hypomagnesemia
Description
Hypomagnesemia is defined as a serum magnesium level less than 1.8 mg/dl. Hypomagnesemia may result from inadequate magnesium intake, increased gastrointestinal or renal losses, or redistribution from extracellular to intracellular space.
Category
Inherited metabolic disease
Brite
Human diseases [BR:br08402]
 Congenital disorders of metabolism
  Other congenital disorders of metabolism
   H01210  Hypomagnesemia
Human diseases in ICD-10 classification [BR:br08403]
 4. Endocrine, nutritional and metabolic diseases (E00-E90)
  E70-E90  Metabolic disorders
   E83  Disorders of mineral metabolism
    H01210  Hypomagnesemia
BRITE hierarchy
Pathway
hsa04978 Mineral absorption  
 
Focal adhesion
Cell adhesion molecules (CAMs)
Tight junction
Gap junction
Gene
TRPM6 [HSA:140803] [KO:K04981]
FXYD2 [HSA:486] [KO:K01538]
CLDN16 [HSA:10686] [KO:K06087]
EGF [HSA:1950] [KO:K04357]
CLDN19 [HSA:149461] [KO:K06087]
Env factor
Furosemide [DR:D00331]
Drug
Magnesium sulfate [DR:D01108]
Comment
Gitelman syndrome is described in H00240. [DS:H00240]
Other DBs
Reference
  Authors
Assadi F
  Title
Hypomagnesemia: an evidence-based approach to clinical cases.
  Journal
Iran J Kidney Dis 4:13-9 (2010)
Reference
PMID:24699222 (gene)
  Authors
Arjona FJ, de Baaij JH, Schlingmann KP, Lameris AL, van Wijk E, Flik G, Regele S, Korenke GC, Neophytou B, Rust S, Reintjes N, Konrad M, Bindels RJ, Hoenderop JG
  Title
CNNM2 mutations cause impaired brain development and seizures in patients with hypomagnesemia.
  Journal
PLoS Genet 10:e1004267 (2014)
DOI:10.1371/journal.pgen.1004267

» Japanese version

DBGET integrated database retrieval system