KEGG   DISEASE: Growth delay due to insulin-like growth factor I resistanceHelp
H01274                      Disease                                

Growth delay due to insulin-like growth factor I resistance;
IGF-I resistance
Growth delay due to IGF-I resistance is characterised by variable prenatal and postnatal growth retardation and elevated serum IGF-I levels. It has been described that the defects in the IGF-IR gene cause postnatal growth failure.
Endocrine disease
Human diseases [BR:br08402]
 Endocrine and metabolic diseases
  Hypothalamus and pituitary gland diseases
   H01274  Growth delay due to insulin-like growth factor I resistance
Human diseases in ICD-10 classification [BR:br08403]
 4. Endocrine, nutritional and metabolic diseases (E00-E90)
  E20-E35  Disorders of other endocrine glands
   E34  Other endocrine disorders
    H01274  Growth delay due to insulin-like growth factor I resistance
BRITE hierarchy
hsa04114  Oocyte meiosis
hsa04510  Focal adhesion
hsa04520  Adherens junction
hsa04730  Long-term depression
hsa04914  Progesterone-mediated oocyte maturation
IGF1R [HSA:3480] [KO:K05087]
Other DBs
ICD-10: E34.3
MeSH: C564816
OMIM: 270450
Abuzzahab MJ, Schneider A, Goddard A, Grigorescu F, Lautier C, Keller E, Kiess W, Klammt J, Kratzsch J, Osgood D, Pfaffle R, Raile K, Seidel B, Smith RJ, Chernausek SD
IGF-I receptor mutations resulting in intrauterine and postnatal growth retardation.
N Engl J Med 349:2211-22 (2003)
Kawashima Y, Kanzaki S, Yang F, Kinoshita T, Hanaki K, Nagaishi J, Ohtsuka Y, Hisatome I, Ninomoya H, Nanba E, Fukushima T, Takahashi S
Mutation at cleavage site of insulin-like growth factor receptor in a short-stature child born with intrauterine growth retardation.
J Clin Endocrinol Metab 90:4679-87 (2005)

» Japanese version

DBGET integrated database retrieval system