KEGG   DISEASE: Acute encephalitisHelp
Entry
H01417                      Disease                                

Name
Acute encephalitis
Description
Acute encephalitis is a serious form of neurological disease caused by inflammation of the brain parenchyma. It is generally characterized by the acute onset of fever, altered mental status, new onset of focal neurological symptoms, and generalized or focal seizures. It can be produced by various etiologies, but viral infection and autoimmune disorders are the most common. Causes of acute viral encephalitis are herpes simplex virus, other herpes viruses, adenoviruses, influenza A, and so on. Mortality rates range between 7 % and 18 %, and severe disability has been reported in up to 56 % of survivors.
Category
Infectious disease; Immune system disease
Brite
Infectious diseases [BR:br08401]
 Viral infections
  Infections caused by dsDNA viruses
   H01417  Acute encephalitis
Human diseases in ICD-10 classification [BR:br08403]
 6. Diseases of the nervous system (G00-G99)
  G00-G09  Inflammatory diseases of the central nervous system
   G04  Encephalitis, myelitis and encephalomyelitis
    H01417  Acute encephalitis
BRITE hierarchy
Pathogen
Herpesvirus
Mastadenovirus
Influenza A virus
Arboviruse
Drug
Acyclovir [DG:DG00406]
Ganciclovir [DG:DG00646]
Other DBs
ICD-10: 
Reference
PMID:14978145 (description, pathogen)
  Authors
Kennedy PG
  Title
Viral encephalitis: causes, differential diagnosis, and management.
  Journal
J Neurol Neurosurg Psychiatry 75 Suppl 1:i10-5 (2004)
DOI:10.1136/jnnp.2003.034280
Reference
PMID:25540320 (description)
  Authors
Singh TD, Fugate JE, Rabinstein AA
  Title
The spectrum of acute encephalitis: Causes, management, and predictors of outcome.
  Journal
Neurology 84:359-66 (2015)
DOI:10.1212/WNL.0000000000001190
Reference
PMID:15804262 (drug)
  Authors
Steiner I, Budka H, Chaudhuri A, Koskiniemi M, Sainio K, Salonen O, Kennedy PG
  Title
Viral encephalitis: a review of diagnostic methods and guidelines for management.
  Journal
Eur J Neurol 12:331-43 (2005)
DOI:10.1111/j.1468-1331.2005.01126.x

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