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Entry
dse00230                    Pathway                                

Name
Purine metabolism - Drosophila sechellia
Class
Metabolism; Nucleotide metabolism
BRITE hierarchy
Pathway map
Purine metabolism
dse00230

All organismsOrtholog table
Module
PRPP biosynthesis, ribose 5P => PRPP [PATH:dse00230]
Inosine monophosphate biosynthesis, PRPP + glutamine => IMP [PATH:dse00230]
Adenine ribonucleotide biosynthesis, IMP => ADP,ATP [PATH:dse00230]
Guanine ribonucleotide biosynthesis IMP => GDP,GTP [PATH:dse00230]
Purine degradation, xanthine => urea [PATH:dse00230]
Other DBs
BSID: 
GO: 
Organism
Drosophila sechellia [GN:dse]
Gene
GM24384 gene product from transcript GM24384-RA; K13988 ADP-ribose pyrophosphatase [EC:3.6.1.13] [KO:K13988] [EC:3.6.1.13]
GM24444 gene product from transcript GM24444-RA; K01835 phosphoglucomutase [EC:5.4.2.2] [KO:K01835] [EC:5.4.2.2]
GM20631 gene product from transcript GM20631-RA; K01835 phosphoglucomutase [EC:5.4.2.2] [KO:K01835] [EC:5.4.2.2]
GM24850 gene product from transcript GM24850-RA; K00948 ribose-phosphate pyrophosphokinase [EC:2.7.6.1] [KO:K00948] [EC:2.7.6.1]
GM13811 gene product from transcript GM13811-RA; K00764 amidophosphoribosyltransferase [EC:2.4.2.14] [KO:K00764] [EC:2.4.2.14]
GM10447 gene product from transcript GM10447-RA; K00764 amidophosphoribosyltransferase [EC:2.4.2.14] [KO:K00764] [EC:2.4.2.14]
GM13655 gene product from transcript GM13655-RA; K11787 phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:6.3.4.13 2.1.2.2 6.3.3.1] [KO:K11787] [EC:6.3.3.1 2.1.2.2 6.3.4.13]
GM17967 gene product from transcript GM17967-RA; K01952 phosphoribosylformylglycinamidine synthase [EC:6.3.5.3] [KO:K01952] [EC:6.3.5.3]
GM11535 gene product from transcript GM11535-RA; K01587 phosphoribosylaminoimidazole carboxylase / phosphoribosylaminoimidazole-succinocarboxamide synthase [EC:4.1.1.21 6.3.2.6] [KO:K01587] [EC:6.3.2.6 4.1.1.21]
GM15393 gene product from transcript GM15393-RA; K01756 adenylosuccinate lyase [EC:4.3.2.2] [KO:K01756] [EC:4.3.2.2]
GM26640 gene product from transcript GM26640-RA; K00602 phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10] [KO:K00602] [EC:3.5.4.10 2.1.2.3]
GM14157 gene product from transcript GM14157-RA; K00759 adenine phosphoribosyltransferase [EC:2.4.2.7] [KO:K00759] [EC:2.4.2.7]
GM22819 gene product from transcript GM22819-RA; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
GM21782 gene product from transcript GM21782-RA; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
GM18318 gene product from transcript GM18318-RA; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
GM21781 gene product from transcript GM21781-RA; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
GM11455 gene product from transcript GM11455-RA; K01081 5'-nucleotidase [EC:3.1.3.5] [KO:K01081] [EC:3.1.3.5]
GM14117 gene product from transcript GM14117-RA; K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03783] [EC:2.4.2.1]
GM15517 gene product from transcript GM15517-RA; K03783 purine-nucleoside phosphorylase [EC:2.4.2.1] [KO:K03783] [EC:2.4.2.1]
GM11429 gene product from transcript GM11429-RA; K00088 IMP dehydrogenase [EC:1.1.1.205] [KO:K00088] [EC:1.1.1.205]
GM23827 gene product from transcript GM23827-RA; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] [KO:K00940] [EC:2.7.4.6]
GM12123 gene product from transcript GM12123-RA; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] [KO:K00940] [EC:2.7.4.6]
GM17681 gene product from transcript GM17681-RA; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] [KO:K00940] [EC:2.7.4.6]
GM16421 gene product from transcript GM16421-RA; K00940 nucleoside-diphosphate kinase [EC:2.7.4.6] [KO:K00940] [EC:2.7.4.6]
GM23945 gene product from transcript GM23945-RA; K12304 soluble calcium-activated nucleotidase 1 [EC:3.6.1.6] [KO:K12304] [EC:3.6.1.6]
GM18184 gene product from transcript GM18184-RA; K01511 ectonucleoside triphosphate diphosphohydrolase 5/6 [EC:3.6.1.6] [KO:K01511] [EC:3.6.1.6]
GM18051 gene product from transcript GM18051-RA; K01519 inosine triphosphate pyrophosphatase [EC:3.6.1.19] [KO:K01519] [EC:3.6.1.19]
GM24078 gene product from transcript GM24078-RA; K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] [KO:K00106] [EC:1.17.3.2 1.17.1.4]
GM25761 gene product from transcript GM25761-RA; K00106 xanthine dehydrogenase/oxidase [EC:1.17.1.4 1.17.3.2] [KO:K00106] [EC:1.17.3.2 1.17.1.4]
GM12103 gene product from transcript GM12103-RA; K01518 bis(5'-nucleosidyl)-tetraphosphatase [EC:3.6.1.17] [KO:K01518] [EC:3.6.1.17]
GM23268 gene product from transcript GM23268-RA; K01951 GMP synthase (glutamine-hydrolysing) [EC:6.3.5.2] [KO:K01951] [EC:6.3.5.2]
GM10723 gene product from transcript GM10723-RA; K01487 guanine deaminase [EC:3.5.4.3] [KO:K01487] [EC:3.5.4.3]
GM25224 gene product from transcript GM25224-RA; K00942 guanylate kinase [EC:2.7.4.8] [KO:K00942] [EC:2.7.4.8]
GM24330 gene product from transcript GM24330-RA; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
GM26420 gene product from transcript GM26420-RA; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
GM26421 gene product from transcript GM26421-RA; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
GM18368 gene product from transcript GM18368-RA; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
GM22397 gene product from transcript GM22397-RA; K00873 pyruvate kinase [EC:2.7.1.40] [KO:K00873] [EC:2.7.1.40]
GM11750 gene product from transcript GM11750-RA; K10807 ribonucleoside-diphosphate reductase subunit M1 [EC:1.17.4.1] [KO:K10807] [EC:1.17.4.1]
GM20395 gene product from transcript GM20395-RA; K10808 ribonucleoside-diphosphate reductase subunit M2 [EC:1.17.4.1] [KO:K10808] [EC:1.17.4.1]
GM20204 gene product from transcript GM20204-RA; K02999 DNA-directed RNA polymerase I subunit RPA1 [EC:2.7.7.6] [KO:K02999] [EC:2.7.7.6]
GM16738 gene product from transcript GM16738-RA; K03002 DNA-directed RNA polymerase I subunit RPA2 [EC:2.7.7.6] [KO:K03002] [EC:2.7.7.6]
GM23695 gene product from transcript GM23695-RA; K03000 DNA-directed RNA polymerase I subunit RPA12 [KO:K03000]
GM13771 gene product from transcript GM13771-RA; K03004 DNA-directed RNA polymerase I subunit RPA43 [KO:K03004]
GM15305 gene product from transcript GM15305-RA; K03005 DNA-directed RNA polymerase I subunit RPA49 [KO:K03005]
GM13065 gene product from transcript GM13065-RA; K03006 DNA-directed RNA polymerase II subunit RPB1 [EC:2.7.7.6] [KO:K03006] [EC:2.7.7.6]
GM24152 gene product from transcript GM24152-RA; K03010 DNA-directed RNA polymerase II subunit RPB2 [EC:2.7.7.6] [KO:K03010] [EC:2.7.7.6]
GM15286 gene product from transcript GM15286-RA; K03011 DNA-directed RNA polymerase II subunit RPB3 [KO:K03011]
GM15313 gene product from transcript GM15313-RA; K03012 DNA-directed RNA polymerase II subunit RPB4 [KO:K03012]
GM20482 gene product from transcript GM20482-RA; K03013 DNA-directed RNA polymerases I, II, and III subunit RPABC1 [KO:K03013]
GM10803 gene product from transcript GM10803-RA; K03014 DNA-directed RNA polymerases I, II, and III subunit RPABC2 [KO:K03014]
GM25797 gene product from transcript GM25797-RA; K03015 DNA-directed RNA polymerase II subunit RPB7 [KO:K03015]
GM22401 gene product from transcript GM22401-RA; K03016 DNA-directed RNA polymerases I, II, and III subunit RPABC3 [KO:K03016]
GM24158 gene product from transcript GM24158-RA; K03017 DNA-directed RNA polymerase II subunit RPB9 [KO:K03017]
GM26620 gene product from transcript GM26620-RA; K03007 DNA-directed RNA polymerases I, II, and III subunit RPABC5 [KO:K03007]
GM17133 gene product from transcript GM17133-RA; K03008 DNA-directed RNA polymerase II subunit RPB11 [KO:K03008]
GM20158 gene product from transcript GM20158-RA; K03009 DNA-directed RNA polymerases I, II, and III subunit RPABC4 [KO:K03009]
GM22579 gene product from transcript GM22579-RA; K03018 DNA-directed RNA polymerase III subunit RPC1 [EC:2.7.7.6] [KO:K03018] [EC:2.7.7.6]
GM21328 gene product from transcript GM21328-RA; K03021 DNA-directed RNA polymerase III subunit RPC2 [EC:2.7.7.6] [KO:K03021] [EC:2.7.7.6]
GM24041 gene product from transcript GM24041-RA; K03023 DNA-directed RNA polymerase III subunit RPC3 [KO:K03023]
GM14954 gene product from transcript GM14954-RA; K03026 DNA-directed RNA polymerase III subunit RPC4 [KO:K03026]
GM22337 gene product from transcript GM22337-RA; K14721 DNA-directed RNA polymerase III subunit RPC5 [KO:K14721]
GM18508 gene product from transcript GM18508-RA; K03027 DNA-directed RNA polymerases I and III subunit RPAC1 [KO:K03027]
GM17025 gene product from transcript GM17025-RA; K03020 DNA-directed RNA polymerases I and III subunit RPAC2 [KO:K03020]
GM25288 gene product from transcript GM25288-RA; K03022 DNA-directed RNA polymerase III subunit RPC8 [KO:K03022]
GM24334 gene product from transcript GM24334-RA; K03024 DNA-directed RNA polymerase III subunit RPC7 [KO:K03024]
GM23658 gene product from transcript GM23658-RA; K03025 DNA-directed RNA polymerase III subunit RPC6 [KO:K03025]
GM10998 gene product from transcript GM10998-RA; K02320 DNA polymerase alpha subunit A [EC:2.7.7.7] [KO:K02320] [EC:2.7.7.7]
GM10379 gene product from transcript GM10379-RA; K02321 DNA polymerase alpha subunit B [KO:K02321]
GM25047 gene product from transcript GM25047-RA; K02684 DNA primase small subunit [EC:2.7.7.-] [KO:K02684] [EC:2.7.7.-]
GM22227 gene product from transcript GM22227-RA; K02685 DNA primase large subunit [EC:2.7.7.-] [KO:K02685] [EC:2.7.7.-]
GM24454 gene product from transcript GM24454-RA; K02327 DNA polymerase delta subunit 1 [EC:2.7.7.7] [KO:K02327] [EC:2.7.7.7]
GM14443 gene product from transcript GM14443-RA; K02328 DNA polymerase delta subunit 2 [KO:K02328]
GM14500 gene product from transcript GM14500-RA; K03504 DNA polymerase delta subunit 3 [KO:K03504]
GM26499 gene product from transcript GM26499-RA; K02324 DNA polymerase epsilon subunit 1 [EC:2.7.7.7] [KO:K02324] [EC:2.7.7.7]
GM13889 gene product from transcript GM13889-RA; K02325 DNA polymerase epsilon subunit 2 [EC:2.7.7.7] [KO:K02325] [EC:2.7.7.7]
GM16944 gene product from transcript GM16944-RA; K02326 DNA polymerase epsilon subunit 3 [EC:2.7.7.7] [KO:K02326] [EC:2.7.7.7]
GM15909 gene product from transcript GM15909-RA; K03506 DNA polymerase epsilon subunit 4 [EC:2.7.7.7] [KO:K03506] [EC:2.7.7.7]
GM12255 gene product from transcript GM12255-RA; K01139 guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase [EC:3.1.7.2] [KO:K01139] [EC:3.1.7.2]
GM19207 gene product from transcript GM19207-RA; K01514 exopolyphosphatase [EC:3.6.1.11] [KO:K01514] [EC:3.6.1.11]
GM12038 gene product from transcript GM12038-RA; K08041 adenylate cyclase 1 [EC:4.6.1.1] [KO:K08041] [EC:4.6.1.1]
GM19695 gene product from transcript GM19695-RA; K08042 adenylate cyclase 2 [EC:4.6.1.1] [KO:K08042] [EC:4.6.1.1]
GM16140 gene product from transcript GM16140-RA; K08043 adenylate cyclase 3 [EC:4.6.1.1] [KO:K08043] [EC:4.6.1.1]
GM22165 gene product from transcript GM22165-RA; K08048 adenylate cyclase 8 [EC:4.6.1.1] [KO:K08048] [EC:4.6.1.1]
GM12804 gene product from transcript GM12804-RA; K12318 guanylate cyclase soluble subunit alpha [EC:4.6.1.2] [KO:K12318] [EC:4.6.1.2]
GM12922 gene product from transcript GM12922-RA; K12319 guanylate cyclase soluble subunit beta [EC:4.6.1.2] [KO:K12319] [EC:4.6.1.2]
GM25747 gene product from transcript GM25747-RA; K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] [KO:K12323] [EC:4.6.1.2]
GM15763 gene product from transcript GM15763-RA; K12323 atrial natriuretic peptide receptor A [EC:4.6.1.2] [KO:K12323] [EC:4.6.1.2]
GM11125 gene product from transcript GM11125-RA; K01769 guanylate cyclase, other [EC:4.6.1.2] [KO:K01769] [EC:4.6.1.2]
GM15161 gene product from transcript GM15161-RA; K01769 guanylate cyclase, other [EC:4.6.1.2] [KO:K01769] [EC:4.6.1.2]
GM16033 gene product from transcript GM16033-RA; K01120 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] [KO:K01120] [EC:3.1.4.17]
GM19267 gene product from transcript GM19267-RA; K01120 3',5'-cyclic-nucleotide phosphodiesterase [EC:3.1.4.17] [KO:K01120] [EC:3.1.4.17]
GM10946 gene product from transcript GM10946-RA; K13755 calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase [EC:3.1.4.17] [KO:K13755] [EC:3.1.4.17]
GM12770 gene product from transcript GM12770-RA; K13758 retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta [KO:K13758]
GM25848 gene product from transcript GM25848-RA; K13763 cGMP-specific 3',5'-cyclic phosphodiesterase, invertebrate [EC:3.1.4.35] [KO:K13763] [EC:3.1.4.35]
GM11531 gene product from transcript GM11531-RA; K13761 high affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9 [EC:3.1.4.35] [KO:K13761] [EC:3.1.4.35]
GM17084 gene product from transcript GM17084-RA; K13298 dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11 [EC:3.1.4.17 3.1.4.35] [KO:K13298] [EC:3.1.4.35 3.1.4.17]
GM23154 gene product from transcript GM23154-RA; K01939 adenylosuccinate synthase [EC:6.3.4.4] [KO:K01939] [EC:6.3.4.4]
GM17581 gene product from transcript GM17581-RA; K01490 AMP deaminase [EC:3.5.4.6] [KO:K01490] [EC:3.5.4.6]
GM24000 gene product from transcript GM24000-RA; K00856 adenosine kinase [EC:2.7.1.20] [KO:K00856] [EC:2.7.1.20]
GM24613 gene product from transcript GM24613-RA; K00856 adenosine kinase [EC:2.7.1.20] [KO:K00856] [EC:2.7.1.20]
GM20810 gene product from transcript GM20810-RA; K00856 adenosine kinase [EC:2.7.1.20] [KO:K00856] [EC:2.7.1.20]
GM23784 gene product from transcript GM23784-RA; K01488 adenosine deaminase [EC:3.5.4.4] [KO:K01488] [EC:3.5.4.4]
GM25912 gene product from transcript GM25912-RA; K01488 adenosine deaminase [EC:3.5.4.4] [KO:K01488] [EC:3.5.4.4]
GM24672 gene product from transcript GM24672-RA; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
GM26136 gene product from transcript GM26136-RA; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
GM16084 gene product from transcript GM16084-RA; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
GM18289 gene product from transcript GM18289-RA; K00939 adenylate kinase [EC:2.7.4.3] [KO:K00939] [EC:2.7.4.3]
GM22168 gene product from transcript GM22168-RA; K06928 nucleoside-triphosphatase THEP1 [EC:3.6.1.15] [KO:K06928] [EC:3.6.1.15]
GM12088 gene product from transcript GM12088-RA; K00962 polyribonucleotide nucleotidyltransferase [EC:2.7.7.8] [KO:K00962] [EC:2.7.7.8]
GM19669 gene product from transcript GM19669-RA; K13811 3'-phosphoadenosine 5'-phosphosulfate synthase [EC:2.7.7.4 2.7.1.25] [KO:K13811] [EC:2.7.1.25 2.7.7.4]
GM16558 gene product from transcript GM16558-RA; K00365 urate oxidase [EC:1.7.3.3] [KO:K00365] [EC:1.7.3.3]
GM20486 gene product from transcript GM20486-RA; K07127 5-hydroxyisourate hydrolase [EC:3.5.2.17] [KO:K07127] [EC:3.5.2.17]
GM22893 gene product from transcript GM22893-RA; K01466 allantoinase [EC:3.5.2.5] [KO:K01466] [EC:3.5.2.5]
Compound
C00002  
ATP
C00008  
ADP
C00011  
CO2
C00014  
NH3
C00020  
AMP
C00035  
GDP
C00037  
Glycine
C00039  
DNA
C00044  
GTP
C00046  
RNA
C00048  
Glyoxylate
C00053  
3'-Phosphoadenylyl sulfate
C00054  
Adenosine 3',5'-bisphosphate
C00059  
Sulfate
C00064  
L-Glutamine
C00081  
ITP
C00086  
Urea
C00104  
IDP
C00117  
D-Ribose 5-phosphate
C00119  
5-Phospho-alpha-D-ribose 1-diphosphate
C00130  
IMP
C00131  
dATP
C00144  
GMP
C00147  
Adenine
C00169  
Carbamoyl phosphate
C00206  
dADP
C00212  
Adenosine
C00224  
Adenylyl sulfate
C00242  
Guanine
C00262  
Hypoxanthine
C00286  
dGTP
C00294  
Inosine
C00301  
ADP-ribose
C00330  
Deoxyguanosine
C00360  
dAMP
C00361  
dGDP
C00362  
dGMP
C00366  
Urate
C00385  
Xanthine
C00387  
Guanosine
C00499  
Allantoate
C00559  
Deoxyadenosine
C00575  
3',5'-Cyclic AMP
C00603  
(-)-Ureidoglycolate
C00620  
alpha-D-Ribose 1-phosphate
C00655  
Xanthosine 5'-phosphate
C00700  
XTP
C00802  
Oxalureate
C00942  
3',5'-Cyclic GMP
C01228  
Guanosine 3',5'-bis(diphosphate)
C01260  
P1,P4-Bis(5'-adenosyl) tetraphosphate
C01261  
P1,P4-Bis(5'-guanosyl) tetraphosphate
C01344  
dIDP
C01345  
dITP
C01367  
3'-AMP
C01762  
Xanthosine
C02091  
(S)-Ureidoglycine
C02348  
(R)(-)-Allantoin
C02350  
(S)(+)-Allantoin
C02353  
2',3'-Cyclic AMP
C02718  
N-Formiminoglycine
C03090  
5-Phosphoribosylamine
C03373  
Aminoimidazole ribotide
C03483  
Adenosine tetraphosphate
C03614  
Inosine 5'-tetraphosphate
C03794  
N6-(1,2-Dicarboxyethyl)-AMP
C03838  
5'-Phosphoribosylglycinamide
C04051  
5-Amino-4-imidazolecarboxyamide
C04376  
5'-Phosphoribosyl-N-formylglycinamide
C04392  
P1,P4-Bis(5'-xanthosyl) tetraphosphate
C04494  
Guanosine 3'-diphosphate 5'-triphosphate
C04640  
2-(Formamido)-N1-(5'-phosphoribosyl)acetamidine
C04677  
1-(5'-Phosphoribosyl)-5-amino-4-imidazolecarboxamide
C04734  
1-(5'-Phosphoribosyl)-5-formamido-4-imidazolecarboxamide
C04751  
1-(5-Phospho-D-ribosyl)-5-amino-4-imidazolecarboxylate
C04823  
1-(5'-Phosphoribosyl)-5-amino-4-(N-succinocarboxamide)-imidazole
C05239  
5-Aminoimidazole
C05512  
Deoxyinosine
C05513  
Urate-3-ribonucleoside
C05515  
5-Ureido-4-imidazole carboxylate
C05516  
5-Amino-4-imidazole carboxylate
C05993  
Acetyl adenylate
C06193  
Guanosine 3'-phosphate
C06194  
2',3'-Cyclic GMP
C06195  
Imidazolone
C06196  
2'-Deoxyinosine 5'-phosphate
C06197  
P1,P3-Bis(5'-adenosyl) triphosphate
C06433  
5'-Benzoylphosphoadenosine
C06435  
5'-Butyrylphosphoinosine
C11821  
5-Hydroxyisourate
C12248  
5-Hydroxy-2-oxo-4-ureido-2,5-dihydro-1H-imidazole-5-carboxylate
C15667  
5-Carboxyamino-1-(5-phospho-D-ribosyl)imidazole
Reference
  Authors
Cusa E, Obradors N, Baldoma L, Badia J, Aguilar J.
  Title
Genetic analysis of a chromosomal region containing genes required for assimilation of allantoin nitrogen and linked glyoxylate metabolism in Escherichia coli.
  Journal
J Bacteriol 181:7479-84 (1999)
Reference
  Authors
Xi H, Schneider BL, Reitzer L.
  Title
Purine catabolism in Escherichia coli and function of xanthine dehydrogenase in purine salvage.
  Journal
J Bacteriol 182:5332-41 (2000)
KO pathway
 

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