KEGG   Equus asinus (ass): 106825844
Entry
106825844         CDS       T04645                                 
Symbol
SOS1
Name
(RefSeq) son of sevenless homolog 1 isoform X1
  KO
K03099  son of sevenless
Organism
eai  Equus asinus (ass)
Pathway
eai01521  EGFR tyrosine kinase inhibitor resistance
eai01522  Endocrine resistance
eai04010  MAPK signaling pathway
eai04012  ErbB signaling pathway
eai04014  Ras signaling pathway
eai04062  Chemokine signaling pathway
eai04068  FoxO signaling pathway
eai04072  Phospholipase D signaling pathway
eai04150  mTOR signaling pathway
eai04151  PI3K-Akt signaling pathway
eai04510  Focal adhesion
eai04540  Gap junction
eai04630  JAK-STAT signaling pathway
eai04650  Natural killer cell mediated cytotoxicity
eai04660  T cell receptor signaling pathway
eai04662  B cell receptor signaling pathway
eai04664  Fc epsilon RI signaling pathway
eai04714  Thermogenesis
eai04722  Neurotrophin signaling pathway
eai04810  Regulation of actin cytoskeleton
eai04910  Insulin signaling pathway
eai04912  GnRH signaling pathway
eai04915  Estrogen signaling pathway
eai04917  Prolactin signaling pathway
eai04926  Relaxin signaling pathway
eai04935  Growth hormone synthesis, secretion and action
eai05034  Alcoholism
eai05160  Hepatitis C
eai05161  Hepatitis B
eai05163  Human cytomegalovirus infection
eai05165  Human papillomavirus infection
eai05200  Pathways in cancer
eai05205  Proteoglycans in cancer
eai05206  MicroRNAs in cancer
eai05207  Chemical carcinogenesis - receptor activation
eai05208  Chemical carcinogenesis - reactive oxygen species
eai05210  Colorectal cancer
eai05211  Renal cell carcinoma
eai05213  Endometrial cancer
eai05214  Glioma
eai05215  Prostate cancer
eai05220  Chronic myeloid leukemia
eai05221  Acute myeloid leukemia
eai05223  Non-small cell lung cancer
eai05224  Breast cancer
eai05225  Hepatocellular carcinoma
eai05226  Gastric cancer
eai05231  Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:eai00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    106825844 (SOS1)
   04012 ErbB signaling pathway
    106825844 (SOS1)
   04014 Ras signaling pathway
    106825844 (SOS1)
   04630 JAK-STAT signaling pathway
    106825844 (SOS1)
   04068 FoxO signaling pathway
    106825844 (SOS1)
   04072 Phospholipase D signaling pathway
    106825844 (SOS1)
   04151 PI3K-Akt signaling pathway
    106825844 (SOS1)
   04150 mTOR signaling pathway
    106825844 (SOS1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    106825844 (SOS1)
   04540 Gap junction
    106825844 (SOS1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    106825844 (SOS1)
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    106825844 (SOS1)
   04660 T cell receptor signaling pathway
    106825844 (SOS1)
   04662 B cell receptor signaling pathway
    106825844 (SOS1)
   04664 Fc epsilon RI signaling pathway
    106825844 (SOS1)
   04062 Chemokine signaling pathway
    106825844 (SOS1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    106825844 (SOS1)
   04912 GnRH signaling pathway
    106825844 (SOS1)
   04915 Estrogen signaling pathway
    106825844 (SOS1)
   04917 Prolactin signaling pathway
    106825844 (SOS1)
   04926 Relaxin signaling pathway
    106825844 (SOS1)
   04935 Growth hormone synthesis, secretion and action
    106825844 (SOS1)
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    106825844 (SOS1)
  09159 Environmental adaptation
   04714 Thermogenesis
    106825844 (SOS1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    106825844 (SOS1)
   05206 MicroRNAs in cancer
    106825844 (SOS1)
   05205 Proteoglycans in cancer
    106825844 (SOS1)
   05207 Chemical carcinogenesis - receptor activation
    106825844 (SOS1)
   05208 Chemical carcinogenesis - reactive oxygen species
    106825844 (SOS1)
   05231 Choline metabolism in cancer
    106825844 (SOS1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    106825844 (SOS1)
   05225 Hepatocellular carcinoma
    106825844 (SOS1)
   05226 Gastric cancer
    106825844 (SOS1)
   05214 Glioma
    106825844 (SOS1)
   05221 Acute myeloid leukemia
    106825844 (SOS1)
   05220 Chronic myeloid leukemia
    106825844 (SOS1)
   05211 Renal cell carcinoma
    106825844 (SOS1)
   05215 Prostate cancer
    106825844 (SOS1)
   05213 Endometrial cancer
    106825844 (SOS1)
   05224 Breast cancer
    106825844 (SOS1)
   05223 Non-small cell lung cancer
    106825844 (SOS1)
  09172 Infectious disease: viral
   05161 Hepatitis B
    106825844 (SOS1)
   05160 Hepatitis C
    106825844 (SOS1)
   05163 Human cytomegalovirus infection
    106825844 (SOS1)
   05165 Human papillomavirus infection
    106825844 (SOS1)
  09165 Substance dependence
   05034 Alcoholism
    106825844 (SOS1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    106825844 (SOS1)
   01522 Endocrine resistance
    106825844 (SOS1)
SSDB
Motif
Pfam: RasGEF RasGEF_N RhoGEF PH PH_19 PH_10 IQ_SEC7_PH Takusan
Other DBs
NCBI-GeneID: 106825844
NCBI-ProteinID: XP_044628214
Position
6:complement(33693898..33840605)
AA seq 1333 aa
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESSDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPVEKIHPLLKEVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSAN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHDHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECLKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASNAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDENSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTMLQEEKEEQMRLPSADVYRFAEPDSEENIIFEENMQPKAGIPI
IKAGTVIKLIERLTYHMYADPNFVRTFLTTYRSFCKPQELLSLIIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVNRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLKRHGKELINFSK
RRKVAEITGEIQQYQNQPYCLRVESDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRN
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGASSTTDVCSVFDSDHSSPFHSSSDTVFIQVTLPHGPRSASVSSISL
TKGTDEVPVPPPVPPRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISE
RTSISDPPESPPLLPPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPP
PQTPSPHGTRRHLPSPPLTQEVDLHSIAGPPVPPRQSTSQHIPKLPPKTYKREHTHPSMH
RDGPPLLENAHSS
NT seq 4002 nt   +upstreamnt  +downstreamnt
atgcaggcgcagcagctgccgtacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgccggcgctgaaaaaggtccaggggcaagttcatcctactcttgagtct
agtgatgatgctcttcagtatgttgaggaattaattttgcagttattaaatatgctatgc
caagctcagcctcgaagtgcttcagatgtagaggaacgtgttcaaaaaagtttccctcat
ccgattgataagtgggcaatagctgatgcccagtcagctattgaaaagaggaagcgaaga
aaccctttatctctcccagtagaaaaaattcatcctttattaaaggaggtcctaggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagagtatatttctgcagac
attttaaagctggtagggaattatgtacggaacatacggcattatgaaattacaaaacaa
gatattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatattatctttaactgatgaagaaccttccacctcaggagagcaaact
tattatgatttggtaaaagcatttatggcagaaattcgacaatacataagggaactaaat
ttaattataaaagtttttagagagccctttgtctccaattcaaaattgttttcagctaat
gatgtagaaaatatatttagtcgtatagtagatatacacgaacttagtgtaaagttactg
ggccacatagaagatactgtagaaatgacagatgaaggcagtccccatccattagtagga
agctgctttgaagacttagcagaggaactggcatttgatccatatgaatcatatgctcga
gatattttacgacctggctttcatgatcatttccttagtcagctatcaaagcctggagca
gcactctatttgcagtcaataggcgaaggtttcaaagaagctgttcagtatgttttaccc
aggctacttctagcccctgtttaccactgtctacattactttgaacttttgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggaatgtttgaaacaagcaataacagctttg
cttaatgttcagagtggtatggaaaaaatatgttctaaaagtcttgcaaaacgaagactg
agtgaatctgcatgtcggttttatagtcagcaaatgaaggggaaacaactagcaatcaag
aaaatgaacgagattcagaagaatattgatggatgggagggaaaagacattggacagtgt
tgcaatgagtttataatggaaggaactcttacacgtgtaggagccaaacatgagagacac
atatttctctttgatggcttaatgatttgctgtaaatcgaatcatgggcaaccaagactt
cctggtgctagcaacgcagaatatcgtcttaaagaaaagttttttatgagaaaggtacaa
attaatgacaaagatgacaccagtgagtacaagcatgcttttgaaataattttaaaagat
gaaaatagtgttatattttctgccaagtcagctgaagagaaaaacaattggatggcagca
ttgatatctttacagtaccggagtacactggaaaggatgcttgatgtgacaatgctacag
gaggagaaggaggagcagatgaggctccctagtgctgatgtttatagatttgcagagccc
gactctgaagagaatattatatttgaagaaaacatgcagcccaaggctggaattccaatt
atcaaagcaggaactgttattaaacttatagagaggctcacataccacatgtatgcagat
cccaattttgttcggacatttcttacaacatacagatccttttgtaaacctcaagaacta
ctgagtcttataatagaaaggtttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcaacccttgagtgcagaactaaaaaggtttagaaaagag
tatatacagcctgtacaactgcgagtattaaatgtatgtcggcactgggtagaacaccac
ttctatgattttgaaagagatgcagatcttttgcagcgaatggaagaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaaaataatccaaaggaaa
aaaattgcaagagacaatggaccaggtcataatattacatttcagagttcacctcccaca
gttgagtggcatataagcagacctgggcacatagagacttttgacctgctcaccttacac
ccaatagaaattgctcgacaacttactttacttgaatcagatctgtatcgagctgtacag
ccatcagaattagttggaagtgtgtggacaaaagaagacaaagaaattaattctcctaat
cttctgaaaatgatccggcacaccactaatctcactttgtggtttgagaaatgtattgta
gaaactgaaaacttagaagaaagagtagctgtggtgaatcgaataattgagattctgcaa
gtctttcaagagctgaacaacttcaatggcgtccttgaggttgttagtgctatgaactca
tcacctgtttacagactagaccacacgtttgagcaaataccaagtcgccaaaagaaaatt
ttagaagaagctcatgaattaagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccatgtgtgcctttctttggaatttatctaactaatatcttgaaaaca
gaagaaggcaaccctgaggtcctgaaaaggcatggaaaagagcttataaactttagcaaa
aggaggaaggtagcagaaattacaggagagatccagcagtaccaaaatcagccttattgt
ttacgagtagaatcggatatcaaaaggttctttgaaaacttgaatccaatgggaaatagc
atggaaaaagaatttacagattatcttttcaacaaatccctagaaatagaaccacgaaat
cctaagcctctcccaagatttccaaaaaaatatagctatcccctaaaatctcctggtgtt
cgtccatcaaacccaagaccaggtaccatgagacatcccacacctctgcagcaggagcca
aggaaaattagttatagtaggatccctgaaagtgaaacagagagtacagcatctgcacca
aattctccaagaacaccgttaacacctcctcctgcttctggtgcttccagtaccacagat
gtttgcagcgtatttgattctgatcattcgagcccttttcactcaagcagcgataccgtc
tttatccaagttacactgccccatggcccaagatctgcttcagtatcatctataagttta
accaaaggcactgatgaagtgcctgtcccccctcctgttcctccacgaagacgaccagaa
tctgccccagcggaatcttcgccatctaagattatgtctaagcatttggacagcccccca
gcaattcctcctaggcaacccacatcaaaagcctattcaccacgctattcaatatcagag
cggacctctatatcagaccctcctgagagccctcccttattaccaccacgagaacctgtg
aggacacctgatgttttctcaagctcaccactacatctccaacctccccctttgggcaaa
aaaagtgaccatggcaatgccttcttcccaaacagcccttctccctttacaccacctcct
cctcaaacaccttctcctcacggcacgagaaggcacctgccgtcaccaccattgacacaa
gaagtggaccttcattccattgctgggccgcctgttcctccacgacaaagcacttctcag
catatccctaaactccctcccaaaacttacaaaagggagcatacacacccatccatgcac
agagatggaccaccactgttggagaatgcccattcttcctga

  All links  
Ontology (1)   
   KEGG BRITE (1)   
Pathway (48)   
   KEGG PATHWAY (48)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (8)   
   Pfam (8)   
All databases (66)   

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