KEGG   Equus asinus (ass): 106831008
Entry
106831008         CDS       T04645                                 
Name
(RefSeq) steroid 21-hydroxylase
  KO
K00513  steroid 21-monooxygenase [EC:1.14.14.16]
Organism
eai  Equus asinus (ass)
Pathway
eai00140  Steroid hormone biosynthesis
eai01100  Metabolic pathways
eai04925  Aldosterone synthesis and secretion
eai04927  Cortisol synthesis and secretion
eai04934  Cushing syndrome
Module
eai_M00109  C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:eai00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    106831008
 09150 Organismal Systems
  09152 Endocrine system
   04925 Aldosterone synthesis and secretion
    106831008
   04927 Cortisol synthesis and secretion
    106831008
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    106831008
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:eai00199]
    106831008
Enzymes [BR:eai01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.16  steroid 21-monooxygenase
     106831008
Cytochrome P450 [BR:eai00199]
 Cytochrome P450, animal type
  CYP21 family
   106831008
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 106831008
NCBI-ProteinID: XP_014696462
Position
8:60528725..60531275
AA seq 493 aa
MLLLGLLLLLILLAGTRLLWGQWKLRSLHLPPLVPGFLHLLQPNLPIYLLGLTQKLGPIY
RLRLGLQAVVVLNSKRTIEEAMIRKWVDFAGRPQLLSYKLVSQRYQDLSLGDYSLLWKAH
KKLTRSALLLGIRNSMEPLVEQLTQEFCERMRAQASAPVAIQKEFSFLTCSIICYLTFGD
KEDTLVHAIQDCVQDLMRTWEHWSIQILDIIPFLRFFPNPGLWRLKQAMKNRDHIIEKQL
RQHKESMVAGRWRDMTDYMLQGLGRPTVEEAPGQLLEGHVHMAMVDLFIGGTETTASTLS
WAVAFLLHHPEIQQRLQDELDRELGPRALGSTVPFKDRARLPLLNATIAEVLRLRPVVPL
ALPHRTTRPTSIVGYDIPKGTIIIPNLQGAHLDETIWEQPHEFRPDRFLYPGASPSTLAF
GCGARVCLGEPLARLELFVVLAQLLRAFTLLPPAGALPSLQPQPHCGVNLTMQPFQVQLQ
PRGAGTPGLGERQ
NT seq 1482 nt   +upstreamnt  +downstreamnt
atgctactccttgggctgctgctgctgctgatcttgctggcaggcacccgcctgctctgg
ggtcagtggaagctcaggagcctccaccttccacctcttgtccctggcttcctgcacctg
ctgcagcccaacctccccatctatctgcttggcttgactcagaaacttgggcctatctac
aggctccgcctcgggctgcaagctgtggtggtgctgaactccaagaggaccattgaagaa
gccatgatcaggaagtgggtggactttgctggcagaccccagttactatcttataagctg
gtgtctcaacgctaccaggatctctcactaggggactattccctgctctggaaggcccat
aagaaactcacccgctcggccctgctactgggcatccgcaactccatggagcccctggtg
gaacagctgacccaagagttctgcgagcgcatgagagcccaggccagtgcccccgtggcc
atccagaaggaattctctttcctcacctgcagcatcatctgttacctcacttttggagac
aaggaagacaccttagtacatgccattcaggactgtgtccaggacttgatgagaacctgg
gaacactggtccatccaaattctggacatcattccctttctcaggttcttccccaaccca
ggcctctggagactgaagcaggccatgaagaacagagatcacatcatagagaagcagctg
aggcagcacaaggagagcatggtggcaggccggtggagggacatgacagactacatgctc
caaggactgggcaggccgacagtggaagaggcccctggacagctccttgaagggcacgtg
catatggctatggtggaccttttcatcggtggaacggagaccactgcgagcaccctctcc
tgggctgtggcattcttgcttcaccaccctgagattcagcagcgactgcaggacgagttg
gatcgtgagctgggccccagagccttgggctccacagtcccattcaaagaccgcgcacgg
ctacccttgctcaacgccactatcgccgaggtgctgcgcctgcggccggtcgtacccctg
gccttgccgcaccgcaccacgcggcctaccagcatcgtcggctacgacatccccaagggc
acaatcattatccccaacctccaaggcgcccacctggatgagacgatttgggagcagccg
cacgagttccggccggaccgcttcctgtaccccggcgccagccccagcacgctcgccttc
ggctgcggggcgcgcgtgtgcctgggcgagccgctggcgcgcctcgagctcttcgtggtg
ctggcgcagctgctccgcgccttcacgctgctgccgcccgccggcgccctgccctctttg
cagccccagccccactgcggcgtcaacctcaccatgcagcctttccaggtgcagctgcag
ccccgtggagcggggaccccgggcctgggcgagcgccagtga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (7)   
   KEGG PATHWAY (5)   
   KEGG MODULE (2)   
Chemical substance (16)   
   KEGG COMPOUND (16)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (6)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (1)   
   Pfam (1)   
All databases (41)   

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