KEGG   ENZYME: 1.1.1.106Help
Entry
EC 1.1.1.106                Enzyme                                 

Name
pantoate 4-dehydrogenase;
pantoate dehydrogenase;
pantothenase;
D-pantoate:NAD+ 4-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
(R)-pantoate:NAD+ 4-oxidoreductase
Reaction(IUBMB)
(R)-pantoate + NAD+ = (R)-4-dehydropantoate + NADH + H+ [RN:R02471]
Reaction(KEGG)
Substrate
(R)-pantoate [CPD:C00522];
NAD+ [CPD:C00003]
Product
(R)-4-dehydropantoate [CPD:C01053];
NADH [CPD:C00004];
H+ [CPD:C00080]
History
EC 1.1.1.106 created 1972, modified 1976
Pathway
Pantothenate and CoA biosynthesis
Reference
1  [PMID:4287370]
  Authors
Goodhue CT, Snell EE.
  Title
The bacterial degradation of pantothenic acid. 3. Enzymatic formation of aldopantoic acid.
  Journal
Biochemistry. 5 (1966) 403-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-38-7

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