KEGG   ENZYME: 1.1.1.115Help
Entry
EC 1.1.1.115                Enzyme                                 

Name
ribose 1-dehydrogenase (NADP+);
D-ribose dehydrogenase (NADP+);
NADP+-pentose-dehydrogenase;
ribose 1-dehydrogenase (NADP+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-ribose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-ribose + NADP+ + H2O = D-ribonate + NADPH + H+ [RN:R01079]
Reaction(KEGG)
Substrate
D-ribose [CPD:C00121];
NADP+ [CPD:C00006];
H2O [CPD:C00001]
Product
D-ribonate [CPD:C01685];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts, more slowly, on D-xylose and other pentoses.
History
EC 1.1.1.115 created 1972
Reference
1  [PMID:4381350]
  Authors
Scher BM, Horecker BL.
  Title
Pentose metabolism in Candida. 3. The triphosphopyridine nucleotide-specific polyol dehydrogenase of Candida utilis.
  Journal
Arch. Biochem. Biophys. 116 (1966) 117-28.
Reference
2  [PMID:4393642]
  Authors
Schiwara HW, Domschke W, Domagk GF.
  Title
[Sugar dehydrogenases in mammalian liver. I. Differentiation of various sugar dehydrogenases from pig liver by disc electrophoresis and ion exchange chromatography]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 349 (1968) 1575-81.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-46-7

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