KEGG   ENZYME: 1.1.1.120Help
Entry
EC 1.1.1.120                Enzyme                                 

Name
galactose 1-dehydrogenase (NADP+);
D-galactose dehydrogenase (NADP+);
galactose 1-dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-galactose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-galactose + NADP+ = D-galactono-1,5-lactone + NADPH + H+ [RN:R01096]
Reaction(KEGG)
R01096;
(other) R01097
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Substrate
D-galactose [CPD:C00124];
NADP+ [CPD:C00006]
Product
D-galactono-1,5-lactone [CPD:C02669];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on L-arabinose, 6-deoxy- and 2-deoxy-D-galactose.
History
EC 1.1.1.120 created 1972
Pathway
Galactose metabolism
Metabolic pathways
Orthology
K22215  
galactose dehydrogenase
Genes
MTHD: 
CMAI: 
MARS: 
TSN: 
MLO: 
MLN: 
MCI: 
MOP: 
MAM: 
MAMO: 
MESO: 
MESW: 
MES: 
HOE: 
AAK: 
SME: 
SMK: 
SMQ: 
SMX: 
SMI: 
SMEG: 
SMEL: 
SMER: 
SMD: 
RHI: 
SFH: 
SFD: 
SIX: 
SAME: 
SINO: 
EAD: 
EAH: 
ESJ: 
ATU: 
Atu0705(fabG)
ARA: 
Arad_1105(fabG1)
ATF: 
ATA: 
AGR: 
ARO: 
RET: 
REC: 
REL: 
REI: 
REP: 
RLE: 
RLT: 
RLG: 
RLB: 
RLU: 
RTR: 
RIR: 
RHL: 
LPU83_0965(fabG1)
RGA: 
RHN: 
RPHA: 
RHT: 
NT26_3705(fabG)
RHX: 
NGL: 
NGG: 
SHZ: 
SIT: 
RSP: 
RSH: 
RSQ: 
RSK: 
JAN: 
RDE: 
RLI: 
DSH: 
PSF: 
PGA: 
PGL: 
PGD: 
PHP: 
PPIC: 
PTP: 
MALG: 
PPHR: 
HAT: 
LAP: 
LAGG: 
LABR: 
SPSE: 
TOM: 
RMM: 
LVS: 
AHT: 
NAO: 
 » show all
Taxonomy
Reference
1  [PMID:5845847]
  Authors
Cline AL, Hu AS.
  Title
The isolation of three sugar dehydrogenases from a psuedomonad.
  Journal
J. Biol. Chem. 240 (1965) 4488-92.
Reference
2  [PMID:5845848]
  Authors
Cline AL, Hu AS.
  Title
Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad.
  Journal
J. Biol. Chem. 240 (1965) 4493-7.
Reference
3  [PMID:5845849]
  Authors
Cline AL, Hu AS.
  Title
Some physical properties of three sugar dehydrogenases from a pseudomonad.
  Journal
J. Biol. Chem. 240 (1965) 4498-502.
Reference
4  [PMID:4387016]
  Authors
Schiwara HW, Domagk GF.
  Title
[Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 349 (1968) 1321-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-51-4

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