KEGG   ENZYME: 1.1.1.120Help
Entry
EC 1.1.1.120                Enzyme                                 

Name
galactose 1-dehydrogenase (NADP+);
D-galactose dehydrogenase (NADP+);
galactose 1-dehydrogenase (NADP)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
D-galactose:NADP+ 1-oxidoreductase
Reaction(IUBMB)
D-galactose + NADP+ = D-galactono-1,5-lactone + NADPH + H+ [RN:R01096]
Reaction(KEGG)
R01096;
(other) R01097
Show
Substrate
D-galactose [CPD:C00124];
NADP+ [CPD:C00006]
Product
D-galactono-1,5-lactone [CPD:C02669];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Also acts on L-arabinose, 6-deoxy- and 2-deoxy-D-galactose.
History
EC 1.1.1.120 created 1972
Pathway
Galactose metabolism
Metabolic pathways
Reference
1  [PMID:5845847]
  Authors
Cline AL, Hu AS.
  Title
The isolation of three sugar dehydrogenases from a psuedomonad.
  Journal
J. Biol. Chem. 240 (1965) 4488-92.
  Organism
Pseudomonas sp.
Reference
2  [PMID:5845848]
  Authors
Cline AL, Hu AS.
  Title
Enzymatic characterization and comparison of three sugar dehydrogenases from a pseudomonad.
  Journal
J. Biol. Chem. 240 (1965) 4493-7.
  Organism
Pseudomonas sp.
Reference
3  [PMID:5845849]
  Authors
Cline AL, Hu AS.
  Title
Some physical properties of three sugar dehydrogenases from a pseudomonad.
  Journal
J. Biol. Chem. 240 (1965) 4498-502.
  Organism
Pseudomonas sp.
Reference
4  [PMID:4387016]
  Authors
Schiwara HW, Domagk GF.
  Title
[Degradation of deoxysurgars by bacterial enzymes. V. Purification and characterization of an NADP-dependent abequose dehydrogenase from Pseudomonas putida]
  Journal
Hoppe. Seylers. Z. Physiol. Chem. 349 (1968) 1321-9.
  Organism
Pseudomonas putida
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-51-4

DBGET integrated database retrieval system