KEGG   ENZYME: 1.1.1.126Help
Entry
EC 1.1.1.126                Enzyme                                 

Name
2-dehydro-3-deoxy-D-gluconate 6-dehydrogenase;
2-keto-3-deoxy-D-gluconate dehydrogenase;
2-keto-3-deoxygluconate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
2-dehydro-3-deoxy-D-gluconate:NADP+ 6-oxidoreductase
Reaction(IUBMB)
2-dehydro-3-deoxy-D-gluconate + NADP+ = (4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate + NADPH + H+ [RN:R01543]
Reaction(KEGG)
Substrate
2-dehydro-3-deoxy-D-gluconate [CPD:C00204];
NADP+ [CPD:C00006]
Product
(4S,5S)-4,5-dihydroxy-2,6-dioxohexanoate [CPD:C04471];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.126 created 1972
Reference
1  [PMID:14488585]
  Authors
PREISS J, ASHWELL G.
  Title
Alginic acid metabolism in bacteria. II. The enzymatic reduction of 4-deoxy-L-erythro-5-hexoseulose uronic acid to 2-keto-3-deoxy-D-gluconic acid.
  Journal
J. Biol. Chem. 237 (1962) 317-21.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-55-8

DBGET integrated database retrieval system