KEGG   ENZYME: 1.1.1.134Help
Entry
EC 1.1.1.134                Enzyme                                 

Name
dTDP-6-deoxy-L-talose 4-dehydrogenase (NADP+);
thymidine diphospho-6-deoxy-L-talose dehydrogenase;
TDP-6-deoxy-L-talose dehydrogenase;
dTDP-6-deoxy-L-talose dehydrogenase (4-reductase);
dTDP-6-deoxy-L-talose:NADP+ 4-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
dTDP-6-deoxy-beta-L-talose:NADP+ 4-oxidoreductase
Reaction(IUBMB)
dTDP-6-deoxy-beta-L-talose + NADP+ = dTDP-4-dehydro-beta-L-rhamnose + NADPH + H+ [RN:R02776]
Reaction(KEGG)
Substrate
dTDP-6-deoxy-beta-L-talose [CPD:C03187];
NADP+ [CPD:C00006]
Product
dTDP-4-dehydro-beta-L-rhamnose [CPD:C00688];
NADPH [CPD:C00005];
H+ [CPD:C00080]
Comment
Oxidation on the 4-position of the hexose moiety takes place only while the substrate is bound to another enzyme that catalyses epimerization at C-3 and C-5.
History
EC 1.1.1.134 created 1972
Reference
1  [PMID:4199258]
  Authors
Gaugler RW, Gabriel O.
  Title
Biological mechanisms involved in the formation of deoxy sugars. VII. Biosynthesis of 6-deoxy-L-talose.
  Journal
J. Biol. Chem. 248 (1973) 6041-9.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-65-0

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