KEGG   ENZYME: 1.1.1.135Help
Entry
EC 1.1.1.135                Enzyme                                 

Name
GDP-6-deoxy-D-talose 4-dehydrogenase;
guanosine diphospho-6-deoxy-D-talose dehydrogenase;
GDP-6-deoxy-D-talose:NAD(P)+ 4-oxidoreductase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
BRITE hierarchy
Sysname
GDP-6-deoxy-alpha-D-talose:NAD(P)+ 4-oxidoreductase
Reaction(IUBMB)
GDP-6-deoxy-alpha-D-talose + NAD(P)+ = GDP-4-dehydro-alpha-D-rhamnose + NAD(P)H + H+ [RN:R03396 R03398]
Reaction(KEGG)
Substrate
GDP-6-deoxy-alpha-D-talose [CPD:C02977];
NAD+ [CPD:C00003];
NADP+ [CPD:C00006]
Product
GDP-4-dehydro-alpha-D-rhamnose [CPD:C01222];
NADH [CPD:C00004];
NADPH [CPD:C00005];
H+ [CPD:C00080]
History
EC 1.1.1.135 created 1972, modified 1976
Pathway
Fructose and mannose metabolism
Amino sugar and nucleotide sugar metabolism
Reference
1  [PMID:14209931]
  Authors
MARKOVITZ A.
  Title
BIOSYNTHESIS OF GUANOSINE DIPHOSPHATE D-RHAMNOSE AND GUANOSINE DIPHOSPHATE D-TALOMETHYLOSE FROM GUANOSINE DIPHOSPHATE ALPHA-D-MANNOSE.
  Journal
J. Biol. Chem. 239 (1964) 2091-8.
Other DBs
ExplorEnz - The Enzyme Database: 
IUBMB Enzyme Nomenclature: 
ExPASy - ENZYME nomenclature database: 
BRENDA, the Enzyme Database: 
CAS: 
37250-66-1

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